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[PDF] Top 20 Dexamethasone in hyperleukocytic acute myeloid leukemia

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Dexamethasone in hyperleukocytic acute myeloid leukemia

Dexamethasone in hyperleukocytic acute myeloid leukemia

... enrichment in the dexamethasone Figure 4. Activity of dexamethasone against acute myeloid leukemia ...of dexamethasone on AML cell lines cultured in minimum ... Voir le document complet

12

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities

... | In vitro and in vivo exposure of acute myeloid leukemia (AML) blasts to pomalidomide induce tumor cell death and control leukemia ...cytometry in blood (day 64 post ... Voir le document complet

15

Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients

Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients

... Abstract To address limitations of the currently used reduced-intensity/myeloablative conditioning (RIC/MAC) classi fication scheme we aimed to develop a tool that can capture more standardized the conditioning intensity ... Voir le document complet

12

ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT.

ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT.

... observed in stem cell transplantation and its impact in this set- ting has been extensively ...outcome in MMURD transplantation for acute myeloid leukemia (AML) patients is ... Voir le document complet

8

Aberrant Chloride Intracellular Channel 4 Expression Is Associated With Adverse Outcome in Cytogenetically Normal Acute Myeloid Leukemia

Aberrant Chloride Intracellular Channel 4 Expression Is Associated With Adverse Outcome in Cytogenetically Normal Acute Myeloid Leukemia

... Methods: Acute myeloid leukemia (AML), which starts in the bone marrow, is a group of hematopoietic stem cell ...participates in tumor growth through its microenvironmental ...value ... Voir le document complet

14

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en fr Targeting NPM1c in Acute Myeloid leukemia NPM1C, une cible dans le traitement des leucémies aigues myéloides

... mutated Acute Myeloid Leukemia patients (NPM1-mutant ...promyelocytic leukemia protein (PML) tumor suppressor organizes domains that control proteolysis and P53-driven ...degradation. ... Voir le document complet

241

Impact of physicians' characteristics on decision making in elderly acute myeloid leukemia

Impact of physicians' characteristics on decision making in elderly acute myeloid leukemia

... elderly acute myeloid leukemia(AML) patients (pts) are ...heterogeneity in clinical practice which is still poorly ...none in AML. In behavioral sciences, attitudes towards risk ... Voir le document complet

2

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

... present in normal mammalian tissues and displays significant preclinical anticancer activity in several cancers including acute myeloid leukemia (AML) [ 3 , 4 ...decreased in ... Voir le document complet

15

Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients

Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients

... Acute myeloid leukemia (AML) intensive chemotherapy combined with broad-spectrum antibiotics, leads to gut microbiota dysbiosis promoting pathological conditions and an increased incidence of ... Voir le document complet

12

Survival improvement of secondary acute myeloid leukemia over time: experience from 962 patients included in 13 EORTC-Gimema-HOVON leukemia group trials

Survival improvement of secondary acute myeloid leukemia over time: experience from 962 patients included in 13 EORTC-Gimema-HOVON leukemia group trials

... Secondary acute myeloid leukemia (sAML) describes patients (pts) with a history of malignant or non-malignant disease or AML secondary to environmental, occupational or therapeutic ...established. ... Voir le document complet

3

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

... : In Acute Myeloid Leukemia (AML), a complete response to chemotherapy is usually obtained after conventional chemotherapy but overall patient survival is poor due to highly frequent ... Voir le document complet

19

Co-activation of AMPK and mTORC1 Induce Cytotoxicity in Acute Myeloid Leukemia

Co-activation of AMPK and mTORC1 Induce Cytotoxicity in Acute Myeloid Leukemia

... kills acute myeloid leukemia (AML) cells but spares normal hematopoietic ...interaction in- volving concurrent activation of AMPK and ...GSK621 in primary AML cells and AML cell lines ... Voir le document complet

14

Unrelated donor versus matched sibling donor in adults with acute myeloid leukemia in first relapse: an ALWP-EBMT study

Unrelated donor versus matched sibling donor in adults with acute myeloid leukemia in first relapse: an ALWP-EBMT study

... with acute myeloid leukemia (AML) has improved, disease recur- rence remains the leading cause of treatment failure, with only a minority of patients who durably benefit from current reinduction ... Voir le document complet

9

Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia.

Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia.

... on leukemia cell proliferation remain poorly documented and somehow ...controversial. In this work, we investigated the effect of adhesion to fibronectin on the proliferation of acute myeloid ... Voir le document complet

9

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients.

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients.

... INTRODUCTION Acute myeloid leukemia (AML) is a cytogenetically and molecularly heterogeneous disease characterized by accumulation of a variety of somatically acquired genetic aberrations in ... Voir le document complet

10

Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia

Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia

... secondary acute myeloid leukemia (sAML), occurring after antecedent hematologic diseases, previous chemotherapy or radiation, has an inferior prognosis compared with de novo ...sAML in the ... Voir le document complet

10

Stability of the cell dynamics in acute myeloid leukemia

Stability of the cell dynamics in acute myeloid leukemia

... maturity acute myeloid leukemia ...functionals. In a simpler model of hematopoiesis (without fast self-renewal) our conditions guarantee also global exponential stability with a given decay ... Voir le document complet

22

STAT5-dependent regulation of CDC25A by miR-16 controls proliferation and differentiation in FLT3-ITD acute myeloid leukemia

STAT5-dependent regulation of CDC25A by miR-16 controls proliferation and differentiation in FLT3-ITD acute myeloid leukemia

... actor in proliferation and differentiation in acute myeloid leukemia expressing the FLT3-ITD ...mutation. In this paper we demonstrate that CDC25A level is controlled by a ... Voir le document complet

13

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

... metabolism in AML cells To characterize the transcriptional consequences of EVI1 overexpression in AML, we generated an EVI1-dependent gene signature from murine bone marrow Lin Low cells infected with a ... Voir le document complet

34

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

... Introduction Acute myeloid leukaemia (AML) is a clonal disorder that affects hematopoietic stem cells or myeloid ...cells in the bone marrow and peripheral blood and leads to bone marrow ... Voir le document complet

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