[PDF] Top 20 Developmental regulation of DNA replication initiation in Drosophila

... amplification in the ovarian follicle cells of Drosophila provides a powerful system for the study of metazoan DNA ...gradients of amplified DNA through repeated rounds ... Voir le document complet

... number of limitations, however. First, despite the general con- sensus in conclusions, different origin mapping techniques gen- erated datasets with modest overlap in studies using HeLa cells on a ... Voir le document complet

... control of DNA replication is essential to ensure faithful transmission of genetic material and prevent chromosomal aberrations that can drive cancer progression and developmental ... Voir le document complet

... combination in the spatial distribution of gene ...sequences in a highly dynamic manner to grant cell fate and achieve a specific developmental ...validation of cell fate maps at the ... Voir le document complet

... MET protein was examined with Western blotting performed on S2* cells transfected with Met dsRNA, Met plasmid expression vector, or double transfected with Met dsRNA and Met expression vector. Transfection with Met ... Voir le document complet

... TGP of either the body or the ...duration of cell proliferation in the imaginal discs. Divergent periods of cell proliferation among discs suggest that they may differ in their ... Voir le document complet

... sion of viral genes can be detected and viremia is ...action of p12 and p30 [10]. Persistence and ex- pansion of the provirus mostly occurs by cellular division leading to clonal expansion of ... Voir le document complet

... uman DNA polymerase y (Pol y) is a 290-kDa protein that comprises a carboxy-terminal A-family polymerase domain, which performs template-dependent and -independent DNA synthesis in vitro 1,2 , a ... Voir le document complet

... studied in conditions that differ with their prior environment. Drosophila melanogaster is a prevalent model organism for host-microbiota studies (Douglas 2018 ...). In this species, bacterial ... Voir le document complet

... terminus DNA amplification in a recG ...action of RecG and PriA in the re-establishment of a correctly oriented replication ...broken replication fork repair and ... Voir le document complet

... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet

... Besides, in grape nutrients are not free to diffuse but enclosed in ...likely in artificial medium than in grape berry, leading to different effects on larval ...development. In ... Voir le document complet

... and replication events invisible to population assays, DNA combing-based RFD profiles allow the interrogation of models built on ensemble-averaging ...mode of replication of ... Voir le document complet

... seen in controls at this ...present in the initial imaging ...later in development are also ...segment of the ...representative of high P r sites becomes ...Diameter of glutamate ... Voir le document complet

... ABSTRACT In most animals, steroid hormones are crucial regulators of physiology and developmental life ...dynamics of hormone production. In Drosophila, transient increases ... Voir le document complet

... exist in all cell types of the fly, carrying out specific functions that help establish or maintain proper chromatin states during ...sets of consequences for chromatin in mad1 mutants: (i) ... Voir le document complet

... regulators of cardiac ...binding of Meis factors, perhaps along with a partner Hox factor, at a subset of enhancers at the CP ...implicated in heart development because Meis1 null mice display ... Voir le document complet

... disturbance of the apico-basal polarity of the gut epithelium. In the control L3 larval midgut, Armadillo (Arm, β-Catenin), a component of the adherens junction, marks the basolateral ... Voir le document complet

... prediction of cell fate maps at the whole embryo level require the establishment of an accurate atlas of gene expression patterns throughout development and the identification of the ... Voir le document complet

... step in maintaining genomic stability is that the replicative polymerases replicate DNA in an accurate manner under normal conditions in ...reviewed in Shevelev and Hubscher 2002 ...the ... Voir le document complet