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[PDF] Top 20 Data mining of gene expression changes in Alzheimer brain

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Data mining of gene expression changes in Alzheimer brain

Data mining of gene expression changes in Alzheimer brain

... described in section 5.3 was applied to ratio data set F0, yielding 40 ...genes. Of these, 10 were different clones representing just 3 ...used in this study contain a number of such ... Voir le document complet

32

Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

... overexpression of dPsn in wing disc in the pattern of scalloped (sd) gene, which regulates the expression of a number of targeted genes including wg, the central ... Voir le document complet

20

Multi-objective Evolutionary Optimization for Visual Data Mining with Virtual Reality Spaces: Application to Alzheimer Gene Expressions

Multi-objective Evolutionary Optimization for Visual Data Mining with Virtual Reality Spaces: Application to Alzheimer Gene Expressions

... separable. In fact, the Alzheimer class is surrounded by elements from the Normal ...sharply, in this case by a nonlinear boundary), and also the Alzheimer class is closer and more mixed with ... Voir le document complet

10

Interpreting fuzzy clustering results with virtual reality-based visual data mining: application to microarray gene expression data

Interpreting fuzzy clustering results with virtual reality-based visual data mining: application to microarray gene expression data

... A. Gene Expression Data from Alzheimer’s disease Alzheimer's disease (AD) is a chronic, progressive, debilitating condition which, along with other neuro-degenerative diseases, represents the largest ... Voir le document complet

8

Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain

Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain

... scriptomics data to be used for drug development and disease progression biomarkers should be present in both blood and brain [13, ...the brain signature is masked by non-HD related processes ... Voir le document complet

14

Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor (LSR) in mice brain

Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor (LSR) in mice brain

... University of Lorraine, Vandoeuvre-les-Nancy, Lorraine, France * ...regulation of cholesterol, an essential brain lipid, ensures proper neuronal development and function, as demonstrated by links ... Voir le document complet

16

Mining biological information from 3D gene expression data : the OPTricluster algorithm

Mining biological information from 3D gene expression data : the OPTricluster algorithm

... evaluation of the triclusters identified are performed. The first step of OPTricluster which is in fact optional consists of performing the gene expression data ...noisy ... Voir le document complet

37

Building Virtual Reality Spaces for Visual Data Mining with Hybrid Evolutionary-Classical Optimization: Application to Microarray Gene Expression Data

Building Virtual Reality Spaces for Visual Data Mining with Hybrid Evolutionary-Classical Optimization: Application to Microarray Gene Expression Data

... Visual data mining via the construction of virtual re- ality spaces for the representation of data and knowledge, involves the solution of optimization ...dimensional data ... Voir le document complet

8

Lipotoxic injury differentially regulates brain microvascular gene expression in male mice

Lipotoxic injury differentially regulates brain microvascular gene expression in male mice

... transcriptome changes in response to the WD in the hippocampal microvasculature of male mice including the modulation of protein-coding genes, miRNAs, snoRNAs, and lncRNAs, as well as ... Voir le document complet

27

Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice.

Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice.

... correlated expression patterns in brain areas that are connected ( French and Pavlidis 2011 ...harnessed gene expression data con- tained within the Allen brain atlas to ... Voir le document complet

15

Voxel-based assessments of treatment effects on longitudinal brain changes in the Multidomain Alzheimer Preventive Trial cohort

Voxel-based assessments of treatment effects on longitudinal brain changes in the Multidomain Alzheimer Preventive Trial cohort

... Prediction of Probable Alzheimer Disease in Patients With Symptoms Suggestive of Memory Impairment: Value of the Mini-Mental State ...Archives of Family Medicine 9, ...baseline ... Voir le document complet

21

Virtual Reality Visual Data Mining with Nonlinear Discriminant Neural Networks: Application to Leukemia and Alzheimer Gene Expression Data

Virtual Reality Visual Data Mining with Nonlinear Discriminant Neural Networks: Application to Leukemia and Alzheimer Gene Expression Data

... ETWORKS In the supervised case, a natural choice for representing the l mapping is an NDA neural network [15], [6], [7], ...nature of the class relationships in complex, high dimensional problems ... Voir le document complet

8

Mining gene expression data using domain knowledge

Mining gene expression data using domain knowledge

... Heterogeneous data integration Although a large amount of information is accessible to researchers, it is often difficult to use it because this information is spread over different sources, represented ... Voir le document complet

18

Semi-supervised consensus clustering for gene expression data analysis

Semi-supervised consensus clustering for gene expression data analysis

... tion of a certain gene function is based on current knowledge in the domain ...knowledge of cer- tain existing gene is limited and will gradually be ...pair of genes most likely ... Voir le document complet

14

Gene expression atlas of embryo development in Arabidopsis

Gene expression atlas of embryo development in Arabidopsis

... Stage-speciic gene coexpression networks Since the 15,912 DEGs represent diverse functionalities in an array of biological processes, weighted gene coexpres- sion network analysis (WGCNA) and ... Voir le document complet

14

Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle

Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle

... Results of the present study reveal tissue-selective alterations of GS expression following portacaval ...shunting. In the case of liver, GS activities were reduced to one third ... Voir le document complet

7

Do changes in gene expression contribute to sexual isolation and reinforcement in the house mouse?

Do changes in gene expression contribute to sexual isolation and reinforcement in the house mouse?

... ORIGIN OF MICE INVOLVED IN THIS STUDY . Trapping sites in Jutland ...center of the hybrid zone as defined in Raufaste et al ...borders of the hybrid zone from where our “border ... Voir le document complet

54

Biomedical data retrieval utilizing textual data in a gene expression database by Richard Lu, MD.

Biomedical data retrieval utilizing textual data in a gene expression database by Richard Lu, MD.

... Recognizing that biological information will primarily be consumed and deposited through the web and that finding relevant information will become more important than ever, this[r] ... Voir le document complet

76

A model for gene deregulation detection using expression data

A model for gene deregulation detection using expression data

... CNA data provided by the CoRegNet package, associating to each gene-sample pair a copy number state: 0 for the diploid state (two copies), 1 for a copy number gain, −1 for a copy number loss, and 2 for a ... Voir le document complet

15

Visualization of data structure, domain knowledge and data mining results: application to breast cancer gene expressions

Visualization of data structure, domain knowledge and data mining results: application to breast cancer gene expressions

... set of a. For example, a decision table is any information system of the form A = (U, A ∪ {d}), where d ∈ A is the decision attribute and the elements of A are the condition ...relation IN ... Voir le document complet

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