Haut PDF Data-driven strategies for vaccine design
Data-driven strategies for vaccine design
... We showed using the landscape that observed mutations that allow HIV to escape from broadly neutralizing antibody (bnAb) pressure tend to occur at residues with low escape[r] ...
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Data-driven finite elements for geometry and material design
... or driven by an automated system. Un- fortunately, previous algorithms for accelerating three-dimensional finite element analysis of elastic objects suffer from expensive pre- computation stages that rely ...
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Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: implications for the design of new vaccine strategies.
... used for medicinal recombinant protein ...possibilities for testing the entire HCV E1 and E2 proteins (individually or as a mixture) for original vaccination ...implications for the ...
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Trust Driven Strategies for Privacy by Design
... the strategies pre- sented in this paper and to verify that the privacy requirements are met according to the formal model detailed in ...by design in mind. For example, two com- ponents are not ...
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A framework for data-driven design in a product innovation process: data analysis and visualisation for model-based decision making
... supports for decision is not disputed (Wierzbicki et ...phases for a creative, strategic, and intuitive decision ...reason for the choice in case of group decisions, is identified as the phase that ...
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Performance-driven measurement system design for structural identification
... Measurement-system optimization is performed according to two criteria: load- test costs and the expected number of candidate models. Both objectives need to be minimized. Results are presented in Figure 13. Load-test ...
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Data-driven HRF estimation for encoding and decoding models
... considered for HRF estimation can be subdivided according to the design matrices they use (standard or separate) and the basis they use to generate the estimated HRF (3HRF and ...different design ...
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Behavior-driven optimization techniques for scalable data exploration
... these strategies increased dramatically from the no la- tency case (2 of 12 participants) to 7 seconds of latency and higher (6 of 9 participants for the 14 seconds ...switched strategies part way ...
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Requirements Driven Data Warehouse Design: We Can Go Further
... DW design methods focus on data integration and omit requirements ...DW design methods. In the first generation of DW design, dedicated studies have mainly concerned three phases [9]: logical ...
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Database partitioning strategies for social network data
... The workload driven approach eventually does split the social graph itself and also uses a partitioning heuristic often used to explicitly partition large graphs, bu[r] ...
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Model driven engineering method for SAIA architecture design
... 2.2. Control layer In the control layer, the control activity is based on a description of an ideal envi- ronment view called Input/Output (I/O). It models the state of the environment through data, events and ...
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Economic and environmental strategies for process design
... transparent for the user. In the framework of eco-design modelling, the problem lies in integrating environmental aspects inside ARIANE software, so that emissions can be taken into account in the global ...
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Data Driven Language for Agents Secure Interaction
... Definition 1 (Agent): An agent is a computer system capa- ble of autonomous action in some environment in order to meet its design objectives. From the security point of view, L ACIOS has two objectives: 1) to ...
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Aligning Perspectives and Methods for Value-Driven Design
... considered for this ...spacecraft design for this ...so for the highest cost; these are part of the Pareto Set represented by the black data points towards the top and right in ...
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Data-driven synthesis for object-oriented frameworks
... language for analyzing pro- gram execution statically or ...finding design defects in the code and as such requires detailed knowledge of the ...suitable for program understanding ...specifically ...
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Advances in data-driven models for transportation
... count data from 2017 through a private data request to the MBTA, which provided the average number of passengers board- ing and alighting buses at each stop for each ...matrix. For ...
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Data-Driven Prediction and Design of bZIP Coiled-Coil Interactions
... important for accurate prediction performance. The optimized weights for many residue combinations were close to ...and design protocol used to generate selective bZIP-interacting ...constants ...
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Data-driven calibration of penalties for least-squares regression
... huge for K < K min and reasonable when K ≥ K min ...applied for multiple change points detection by ...known for non Gaussian or heteroscedastic ...
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Data Driven Constitutive identification
... show, for N ∗ = 41 the computed material and mechanical states together with the "true" constitutive relation used to generate the input ...higher for small strains as there are more data ...
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Data-driven task allocation for multi-robot deliveries
... (b) Partitioning and Hubs (0.25, 0.25, 0.25, 0.25) Figure 4-2: Environment used for evaluation of partitioning and hub location algo- rithms. (a) The environment is overlaid by its graph representation, with each ...
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