[PDF] Top 20 Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery

... TSMs and the TSLs, displayed slightly greater cytotoxicity at the higher temperature (45 °C) while NSLs showed no toxic effect on the timescale of the ...DOX and TSLs was significantly enhanced when exposed ... Voir le document complet

... MSNPs and Dox-loaded uncoated MSNPs were normalized to a drug concentration of 2 mg/kg and injected into well-defined ...h and analyzed for Dox-induced apoptosis by measurement of TUNEL ... Voir le document complet

... core and a stimuli- responsive polymer coating, have been frequently suggested as a promising drug delivery system (DDS), due to their outstanding biocompatibility, versatile surface modification, ... Voir le document complet

... copolymers for the simultaneous delivery of drugs with different physicochemical ...hydrophobic and hydrophilic chemotherapeutics and provide both active targeting partially mediated by CD44 ... Voir le document complet

... 2 | Journal Name, [year], [vol], 00–00 This journal is © The Royal Society of Chemistry [year] Biosystems). The instrument is equipped with a pulsed N2 laser (337 nm) and a time-delayed extracted ion source. ... Voir le document complet

... proceed for one day at room temperature and purified by dialysis against ...Results and Discussion The synthesis of the three macromolecular architectures, obtained by the ring-opening polymerization ... Voir le document complet

... polymer and its high diffusivity [ 109 ...USA) and SofLens ® 59 Comfort (Bausch & Lomb, Rochester, NY, ...this drug delivery system obtained with the supercritical solvent impregnation can ... Voir le document complet

... Figure 1-1. Linear-dendritic block copolymers self-assembling into a micelle ... Liposomes are composed of lipid bilayers that are able to encapsulate hydrophilic drug in its [r] ... Voir le document complet

... combinations and time scheduling of in-silico, in-vitro, ex-vivo and in-vivo experimentation may be scientifically ...prerequisite for clinical testing or following the particle path from macroscopy ... Voir le document complet

... concentration and are more prone to sustained drug ...ethylene and a siloxy-functionalized comonomer followed by the removal of the protecting groups produce a hyperbranched polyethylene core ... Voir le document complet

... the tumor vascular ...1B) and telemetric devices to measure systemic blood pressure failed to reveal significant changes following ET A antagonist ...the tumor selectivity of the ET A antagonist was ... Voir le document complet

... Cancer and the Fortis Cancerology Research Fund. Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable parameter to improve ... Voir le document complet

... h for the 5 wt% hydrogel, Figure ...OH and COOH lactide end groups ...protons and the unaffected lactide methine ones (~1/10), and that one PLA segment contains 28 methine protons in average, ... Voir le document complet

... H3 and orange curve n = 4 from human donors H1, ...µM) and unlabeled ...complex and not free fluorescein alone, a control test was done at the end of one run in which free fluorescein was added to ... Voir le document complet

... 3. Delivery spot in the culture plate following a focused ultrasound pulse at various peak negative pressure (a) ...contour and the dotted yellow line is the activation pressure threshold ...spot ... Voir le document complet

... [15] and to study its asymptotic behavior for small ...required for Sections 5 and 6. These results use classical estimates for hyperbolic, elliptic and parabolic ...the ... Voir le document complet

... 19 20 Surface plasmon resonance can be used to manipulate light at the nanoscale. It was used here to trigger 21 photopolymerization of an atom transfer radical polymerization (ATRP) molecular system, leading to a 22 ... Voir le document complet

... In this thesis we designed a small molecule cytosolic delivery platform based on cell-penetrating amphiphilic nanoparticles (amph-NPs), which are capable of embedding w[r] ... Voir le document complet

... isolation and a proton nuclear magnetic resonance study, Biochem Biophys Res Commun 189 (1992) ...Russell and H.M. Johnson, Binding site on the murine IFN-gamma receptor for IFN-gamma has been ... Voir le document complet

... MMAD and significantly increased the FPF from ...of drug administration by DPI ...30.93% for particles composed of AMB-HCl/leucine/mannitol in a ...ratio and made by spray ... Voir le document complet