[PDF] Top 20 A conserved MCM single-stranded DNA binding element is essential for replication initiation
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A conserved MCM single-stranded DNA binding element is essential for replication initiation
... individual MCM subunits do not all simultaneously participate in ssDNA ...with DNA use a consistent binding mode with four nucleotides per subunit ( Figure 1 , Figure 2 , Figure 2—figure ... Voir le document complet
22
Glycolytic pyruvate kinase moonlighting activities in DNA replication initiation and elongation
... evolved a metabolic control of DNA replication to respond to a wide range of nutritional ...(PykA) is intricately linked to ...comprises a catalytic (Cat) domain that binds to ... Voir le document complet
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A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element
... in a host chromosome and can excise and transfer to recipient bacteria via ...nicked single strand of ICE DNA. For ICEBs1 of Bacillus subtilis, nicking of oriT by the ICEBs1 relaxase NicK also ... Voir le document complet
13
HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin
... acetylation is linked to pre-RC assembly and the control of initiation of DNA ...acetylation is involved in origin activation during early development in Xenopus ( Danis et ...alter ... Voir le document complet
11
Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining
... of DNA DSB recognition and repair; signaling and resection DSB signaling At an early step, double-strand break recogni- tion is accomplished by the MRN complex (MRE11, RAD50 and NBS1), which acts in an ... Voir le document complet
21
High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes
... INTRODUCTION Single-stranded binding (SSB) proteins bind with a high affinity to single-stranded DNA (ssDNA), which is a transient state in many DNA ... Voir le document complet
8
Using single-case designs in practical settings: Is replication always necessary?
... within-subject replication through the use of reversal and multielement ...which is central to these designs, may not be desirable, feasible, or even ethical in practical ...datasets for which the ... Voir le document complet
19
DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF
... (QIBC), a high-throughput microscopy method described in Fig 1B [ 14 ...of a population the amounts of several DNA damage markers and to correlate this with the stage of the cell ...], a ... Voir le document complet
17
The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation
... HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ... Voir le document complet
22
Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis
... concerns for drastically varying ββ′ levels. Manganese is known to be able to occupy the iron-binding site of class Ia RNR, resulting in catalytically inactive β 2 ...(45). A possible effect ... Voir le document complet
11
Two distinct conformational states define the interaction of human RAD51‐ATP with single‐stranded DNA
... than a single interface type or a range of different interfaces, is striking and suggests that they might be functionally ...18.4 A ˚ vs. 112 and 16.9 A˚), reflecting a ... Voir le document complet
14
Chimeric viruses blur the borders between the major groups of eukaryotic single-stranded DNA viruses.
... built a three-dimension model of a representative CHIV CP; CHIV10 (Airborne_IC2) was chosen for this purpose ...most conserved part of these proteins corresponds to the S-domain, whereas the ... Voir le document complet
10
Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA
... and single point mutants were overexpressed and purified as for the wild ...reached a value of ...overexpression for 4 hours at 37 uC, cells were harvested by a low speed centrifugation ... Voir le document complet
15
Biochemical characterization of CBF3, an essential DNA-binding component of the yeast kinetochore
... the protein complex CBF3, which bind in a sequence-specific manner to CDEI and CDEIII, respectively, were isolated, and genetic analysis showed that these proteins were inde[r] ... Voir le document complet
107
Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4
... Imai for a lot of advice on immunoprecipitation assays and Fr ´ed ´eric Baudat for help and advice on ...members for insight and discussions. We thank Am ´elie Sarazin for image ... Voir le document complet
14
Tetramerization and interdomain flexibility of the replication initiation controller YabA enables simultaneous binding to multiple partners
... subtilis, replication initiation control is fulfilled by vari- ous proteins, which bind to DnaA and modulate its activity during the different life-styles of the ...prevents replication re- ... Voir le document complet
16
DNA Replication Restart in Archaea
... state for instance, one has to carefully choose the variants that optimally fit the lifestyle of the organism being ...cells for the first ...has a relatively high intracellular salt concentration ... Voir le document complet
25
Evolutionary history of bacteriophages with double-stranded DNA genomes
... see, for example, ...There is no general solution of the average weighting problem yet, but we think that the use of parametric family that we have proposed in ...36 is a sensible starting ... Voir le document complet
14
Targeting of single stranded oligonucleotides through metal-induced cyclization of short complementary strands: Targeting of single stranded oligonucleotides
... an essential secondary structure of RNA often involved in regulation of gene expression ...line is developed here using modified oligonucleotides bearing terminal 2,2':6',2”terpyridines moieties which may ... Voir le document complet
35
Discrete-element model for dynamic fracture of a single particle
... Finite Element Method (FEM) ap- proaches wherein the dynamic meshes make it possible to incor- porate cracks and their evolution in time ( Hillerborg et ...discrete element method (DEM) was used as the ... Voir le document complet
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