... of alcoholism, it is considerably important to determine whether other pre-existing factors influence cognitive function among ...display cognitivedeficits, particularly among executive ...
... and cognitive impairments. Cognitive impairments occur before the onset of psychosis and could reflect glutamatergic ...variations in genes coding for glutamatergic receptors and cognitive ...
... and cognitivedeficits of ...proteins in heterozygous mice (only one allele expressed) would result in abnormal behavior related to those displayed by STOP null ...either in standard ...
... encoding deficits for verbal material in aMCI patients, ...involved in this cognitive ...findings in aMCI using structural data do not perfectly ...
... of deficitsin spatial memory and learning already at 8 months in caffeine exposed Tau ...These deficits occurred at 12 months in water exposed Tau mice and were still present at that ...
... task, in which they are required to sort a number of cards by a rule that changes ...digits in a random ...2004). In the latter task, the participant is asked to mark out a target letter in an ...
... areas in the DS ...discussed in the context of L41 regulation of inhibition/excitation ratios, imbalanced in DYRK1A-overexpressing mice (Souchet et ...quantified in three different DS models ...
... of deficitsin spatial memory and learning already at 8 months in caffeine exposed Tau ...These deficits occurred at 12 months in water exposed Tau mice and were still present at that ...
... obtained in an excitotoxin-mediated lesion model of HD that has already been shown to induce a clear pattern of cell loss in the striatum, a hallmark of HD, ( Beal et ...motor deficits ( Burns et ...
... overnight in PBS at ...post-fixed in potassium ferrocyanide ...overnight in uranyl acetate (1%), washed in distilled water at 50°C, before being stained with lead aspartate at the same ...
... paraformaldehyde in PBS. Brains were post- fixed for 4 h at RT or overnight at 4 °C in the same ...placed in 24-well plates free-floating in ...RT in blocking buffer (5% normal goat ...
... These results suggest that a impairment of inhibitory frontal processes (higher CNV amplitude in Fz than in Cz) could be correlated with a higher level of psychopatholog[r] ...
... (v/v) in 1 ⫻ PBS. Brains were harvested and placed in 4% para- formaldehyde in 1 ⫻ PBS at 4°C for 4 h, and they were kept at 4°C until being sliced using a ...sections in 1 ⫻ PBS (one per well ...
... increase in spine density in the Fmr1 R138Q hippocampus, we did not notice any modification in the overall maturity of the dendritic ...protrusions. In addition, while the surface levels of ...
... involved in this ...tyrosine in position 272 (Y272Δ) or to be involved in the binding to the Pp1 inhibitor I2 (M290K-C291A) or implicated in the binding to two Pp1 binding partners PNUTS and ...
... 32 In addition, 2 raters performed segmentations independently with signi ficant ...changes in brain structure and connectiv- ity, but the histological correlates of these changes are poorly understood and ...
... rats. In the subsequent breedings, APO- SUS rats displayed SZ-relevant features without this pharmacolo- gical ...treatment. In this study, naive male APO-SUS and APO- UNSUS rats from the 32th –44rd ...
... Pyk2 in the hippocampus of HD patients and R6/1 mice ...those in Pyk2 þ / mice, which displayed a similar phenotype, we asked whether correct- ing this defect in R6/1 mice could rescue some of ...
... deletion in mice leads to a phenotype mimicking some aspects of positive symptoms classically observed in schizophrenic ...and cognitive functions in STOP null ...deficit in the ...