Top PDF Circulating antipodocyte antibodies in membranous nephropathy: pathophysiologic and clinical relevance.
Circulating antipodocyte antibodies in membranous nephropathy: pathophysiologic and clinical relevance.
... from a normal control was used instead, no bands appeared (Figure 2 upper right). Dot blotting data were similar to those from Western blotting (Figure 2 lower left); the patient ’s serum but not the normal control ...
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Advances in Membranous Nephropathy
... Abstract: Membranous nephropathy (MN) is a rare auto-immune disease where the glomerulus is targeted by circulating auto-antibodies mostly against podocyte antigens, which results in ...
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A podocyte view of membranous nephropathy: from Heymann nephritis to the childhood human disease
... Advances in medical science often proceed by steps which are highly ...important clinical implications often result from the combination of faithful experimental models and careful clinical ...
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Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials.
... PFS and OS ...accurate in the early phases of a new treatment, whereas CTC spikes have not been ...early in the course of a new therapeutic regimen for metastatic disease appear to reflect response, ...
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Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.
... observed in all high-grade gliomas cultures within two weeks post-seeding, and dominated over anchored ...(h and j) coexisting with cells and cellular aggregates loosely anchored to the ...
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A Pathophysiologic Approach to Biomarkers in Acute Respiratory Distress Syndrome
... formation. In addition, proinflammatory events may also inhibit fibrinolysis and induce platelet acti- vation ...nantly in the alveolar compartment, is found in several acute inflammatory lung ...
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Nrf2-driven CD36 and HO-1 gene expression in circulating monocytes correlates with favourable clinical outcome in pregnancy-associated malaria
... (PPARγ) and the nuclear factor erythroid-derived 2-like 2 (NF-E2L2 or Nrf2) [ 24 , 25 ...PPARγ and Nrf2 [ 26 – 28 ]. Importantly, it was demonstrated in vitro that human and murine macrophages ...
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Vancomycin-Associated Cast Nephropathy
... unclear, in particular when considering the frequent coad- ministration of ...developed in parallel a new immunohistologic staining technique to detect vancomycin in renal tissue and confirmed ...
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Bridging the Gap Between Diabetes and Stroke in Search of High Clinical Relevance Therapeutic Targets
... morbidity and mortality in stroke and is recognized both as risk and aggravating factor in both diabetic and non-diabetic patients (Figure ...stroke in both diabetic ...
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Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas.
... genes and statistical analysis to extract chromosomal pattern of gene ...probes and converts the original expression values in wavelet coefficients that are functions of the expression of adjacent ...
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Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence
... desialylation in human and murine type 2B VWD in vivo To examine the putative link between platelet desialylation and thrombocytopenia in type 2B VWD, we assessed β -galactose exposure ...
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On the impact of domain expertise on query formulation, relevance assessment and retrieval performance in clinical settings
... knowledge and domain ...differences in domain expertise on both search processes ( Bhavnani, 2001; White, Dumais, & Teevan, 2009; Wildemuth, 2004 ) and search difficulty ( Liu, Liu, Cole, Belkin, ...
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The clinical relevance of imatinib plasma trough concentrations in chronic myeloid leukemia. A Belgian study
... Patients and methods This is a retrospective multicenter study performed in Belgian hema- tology departments who volunteered to communicate clinical data on patients with CML treated with IM, ...
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Reifying Relevance in Mild Cognitive Impairment: An Appeal for Care and Caution: Reifying Relevance in MCI
... with well defined dementia symptoms and multiple cognitive and functional impairments who are in need, and benefit from support. Even with these criteria, however, there have been great ...
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Emerging circulating biomarkers in glioblastoma: promises and challenges
... heterogeneous and invasive malignant ...–, and typically shows poorly differentiated glial tumor cells with increased density and mitotic activity, hyperplastic vasculature, and areas of ...
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Antibodies to the conserved C-terminal domain of the Plasmodium falciparum merozoite surface protein 1 and to the merozoite extract and their relationship with in vitro inhibitory antibodies and protection against clinical malaria in a Senegalese village.
... from clinical disease, or to other potentially protective mechanisms targeting other merozoite ...response, and to investigate their association with both growth and/or invasion inhibition in ...
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ANTI-NUCLEAR ANTIBODIES : PREVALENCE OF DIFFERENT PATTERNS AND ANTIBODIES IN A BELGIAN UNIVERSITY LABORATORY
... Antinuclear antibodies (ANA) directed against a variety of nuclear antigens are detected in patients with many systemic autoimmune diseases but also in nonrheumatic ...technique. Antibodies ...
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Experimental and Numerical Models of Complex Clinical Scenarios; Strategies to Improve Relevance and Reproducibility of Joint Replacement Research
... Experimental and Numerical Models of Complex Clinical Scenarios; Strategies to Improve Relevance and Reproducibility of Joint Replacement Research This research review aims to focus attention ...
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Coexistence of circulating HBsAg and anti-HBs antibodies in chronic hepatitis B carriers is not a simple analytical artifact and does not influence HBsAg quantification
... molecular and immunologic mechanisms leading to this serologic profile remain unclear but could be due to the selection of HBV escape mutants by immune pressure ...(6–8). In this scenario, the detected ...
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CXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation
... CsA and Tacrolimus (white and gray boxes, ...(top) and absolute cell numbers (bottom) are displayed for CD4 + lymphocytes, total CD4 + CD45RA − CXCR5 + cTfhs and the three CXCR5 + PD1 + , ...
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