[PDF] Top 20 Characterizing antigen-specific CD4⁺ T cells using HLA-DR oligomers
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Characterizing antigen-specific CD4⁺ T cells using HLA-DR oligomers
... 2000). Cells such as macrophages, neutrophils and monocytes attack pathogens by endocytic and phagocytic mechanisms triggered through cell-surface receptors which are not well understood but are a hot topic of ... Voir le document complet
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CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells
... experiment, CD4 ⫹ T cells purified from a different donor were stimulated three times with 1088mel lysate-pulsed autol- ogous CD40-activated B cells 10 days apart in 1 well of a 48-well ...B ... Voir le document complet
8
en fr Development of cellular immunotherapeutic strategies based on the activation of human CD4+ TL by artificial antigen presenting cells Développement de stratégies d'immunothérapies cellulaires basées sur l'activation de lymphocytes T CD4+ humains à l'aide de cellules présentatrices d'antigène artificielles.
... of characterizing the frameshift mutations present in the tumor of a given ...patient, specific for neopeptides resulting from these mutations, and, in a third step, to check the cytotoxic activity of the ... Voir le document complet
238
MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients
... melanoma antigen containing a HLA-A2 restricted epitope, involved in melanoma immunosurveillance of patients adoptively transferred with tumour infiltrating lymphocytes ...full-length antigen (46 aa) ... Voir le document complet
13
Analysis of the roles of Interleukin 15 and CD4+ T cells specific of a dietary antigen in a mouse model of celiac-like enteropathy
... generate HLA-restricted CD4 T cell responses in the absence of a human CD4 transgene in mice bearing chimeric or fully human HLA-DR or DQ molecules (Woods et ...mouse CD4 and ... Voir le document complet
200
Antigen-Specific Gene Expression Profiles of Peripheral Blood Mononuclear Cells Do Not Reflect Those of T-Lymphocyte Subsets
... Intrasubject comparison of individual gene expression in each cell type. To further highlight the distinct gene expression profiles in the chosen cell populations, we selected genes that were up-regulated in one cell ... Voir le document complet
7
Anti-Gal-mediated targeting of human B lymphoma cells to antigen-presenting cells: a potential method for immunotherapy using autologous tumor cells.
... lymphoma cells. A. Fresh malignant B cells (patient 4 in Table 1) were incubated first with (solid line) or without (dotted line) neuraminidase to remove terminal sialic acid on cell surface ...The ... Voir le document complet
11
MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete.: MHC Class II tetramers
... G.T., Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes 51, 1375-1382, 2002. 18. Meyer, A.L., Trollmo, C., ... Voir le document complet
32
Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage
... T cells from DTg mice and non-Tg BALB 兾c mice. CD4 ⫹ CD25 ⫹ cells from both types of donor mice strongly inhibited the anti-CD3 mAb-induced proliferation of naive CD4 ⫹ CD25 ⫺ T cells ... Voir le document complet
7
Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells.
... T cells [ 28 ] ...studied using ICOS ...tissue specific Treg ...regulatory CD4 T cells, it also allows distinguishing activated conventional T ...increased CD4 T cell numbers in ... Voir le document complet
15
Ito Cells Are Liver-Resident Antigen-Presenting Cells for Activating T Cell Responses
... Ito Cells Express CD1 Molecules and APC Surface Markers In order to investigate the impact of Ito cells on NKT cells, we isolated Ito cells from liver of C57BL/6 mice via the pro- nase and ... Voir le document complet
14
Mechanics of antigen extraction by B cells
... B cells produce antibodies and are therefore essential effectors of adaptive ...neighboring antigen presenting ...B cells to extract and process ...B cells: (1) Membrane spreading followed by ... Voir le document complet
146
Do RA associated HLA-DR molecules bind citrullinated peptides or peptides from PAD4 to help the development of RA specific antibodies to citrullinated proteins?
... purified HLA–DR allele was tested on ELISA plates coated with 10 μ g of peptide from PAD4 or native and citrulli- nated ...synthesized using the solid-phase sys- tem and purified (>60%) ... Voir le document complet
7
Étude transcriptomique des cellules dendritiques CD103+ CD4+ chez le rat transgénique HLA-B27, modèle de la spondylarthrite
... Nous avons quantifié par RT-PCRq l’expression de gènes codant pour A des cytokines et chimiokines et B des facteurs de transcription impliqués dans la voie de signalisation de l’IFN, dan[r] ... Voir le document complet
109
Antigen-specific memory T cell distribution in non-lymphoid tissue
... In this study, we have shown that antigen-specific 2C GFP effector memory CD8+ T cells are generated in B6 recipient mice 30-32 days after influenza virus infection, prefere[r] ... Voir le document complet
36
Carrier-induced, hapten-specific suppression: a problem of antigen presentation?
... of specific Abs were measured in individual ...IgG2a specific for hapten when preimmunized against the carrier, albeit at lower levels than those produced by unprimed mice ... Voir le document complet
12
Characterizing deformability and surface friction of cancer cells
... that cells possessing higher metastatic potential exhibit faster entry velocities than cells with lower metastatic ...cancer cells to ef- ficiently squeeze through tight ...tumor cells spiked ... Voir le document complet
7
Real-time aircraft simulation using HLA standard
... HLA for real-time ? (1/2) HLA is a well-established technique used in the man-machine system area for training and research ; However, works to include real-time specifications and properties to HLA ... Voir le document complet
29
Continuous Activation of the CD122/STAT-5 Signaling Pathway during Selection of Antigen-Specific Regulatory T Cells in the Murine Thymus.
... 6 cells were labeled with 100 m l of a mix of mAbs diluted in PBS containing 3% FCS for 30 minutes at 6–8uC in the ...staining using foxp3 mAb was performed according to the kit manufacturer’s instructions ... Voir le document complet
9
en fr Phenotypic and functional analysis of HIV-specific CD4+ T cells in spontaneously controlled HIV infection Analyses phénotypique et fonctionnelle des cellules T CD4+ spécifiques du VIH chez les patients contrôlant spontanément l’infection à VIH
... CXCR5+ CD4+ T cells, which represents about 10-15% of the blood CD4+ T cell pool in humans, was shown to share functional characteristics with Tfh that reside in lymphoid ...CXCR5+ CD4+ T ... Voir le document complet
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