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[PDF] Top 20 Characterizing and predicting enhancers in the human genome

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Characterizing and predicting enhancers in the human genome

Characterizing and predicting enhancers in the human genome

... Chromatin state data has been collected for the human genome across approximately 90 different cell types.. However, regulatory processes change across different cell types and[r] ... Voir le document complet

31

Investigating the function of histone H2A.Z in the human genome and mechanisms of chromatin incorporation

Investigating the function of histone H2A.Z in the human genome and mechanisms of chromatin incorporation

... Introduction The regulation of chromatin dynamics is a key mechanism that controls essential cellular functions such as gene expression, DNA repair, and replication (Voss and Hager, ...remodelers, ... Voir le document complet

224

Predicting human minisatellite polymorphism.

Predicting human minisatellite polymorphism.

... accelerate the search for highly polymorphic mini- satellites. The goal has been the development of sequence- based predictive criteria for ...on the study of a representative pool of ... Voir le document complet

13

Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome.

Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome.

... cells, the FRA3B region lies within a V-shaped replication timing trough formed by two converging TTRs, each about 1 Mb in length (Figure ...with the mean (1.87 kb/min) and max ...combing ... Voir le document complet

23

Defining functional DNA elements in the human genome

Defining functional DNA elements in the human genome

... although the evolutionary ap- proach has the advantage that it does not require a priori knowledge of what a DNA element does or when it is used, it is un- likely to reveal the molecular mechanisms ... Voir le document complet

9

Structural variations of the human genome and transcriptome induced by LINE-1 retrotransposons

Structural variations of the human genome and transcriptome induced by LINE-1 retrotransposons

... through the dispersion of regulatory elements Cis-regulatory sequences and their evolution is believed to change the transcriptional output and have an impact on speciation ...contribute ... Voir le document complet

195

Characterizing and predicting cortical evoked responses to direct electrical stimulation of the human brain

Characterizing and predicting cortical evoked responses to direct electrical stimulation of the human brain

... interested in characterizing the response to stimula- tion across all recording sites in a simple and tractable model that can be used to predict future ...characterized the ... Voir le document complet

8

Microvirga massiliensis sp nov., the human commensal with the largest genome

Microvirga massiliensis sp nov., the human commensal with the largest genome

... phenotypic and genotypic charac- teristics (Stackebrandt and Ebers 2006; Tindall et ...as the phylogenetic marker 16S rRNA sequence, DNA–DNA hybridization, and DNA G+C content (Rosselló- Mora ... Voir le document complet

17

Bioinformatics approach for the identification of fragile regions on the human genome

Bioinformatics approach for the identification of fragile regions on the human genome

... Studies on the genome synteny have shown that conserved regions are not only significantly enriched in putative regulatory regions (Mongin et al. To infer the evol[r] ... Voir le document complet

109

Identifying and characterizing the ontogenetic component in tree development

Identifying and characterizing the ontogenetic component in tree development

... models and hidden semi-Markov chains share the same segmentation ...However, the main difference between these two families of models is that, while in the case of change-point models, ... Voir le document complet

6

Characterizing Human Shape Variation Using 3-D Anthropometric Data

Characterizing Human Shape Variation Using 3-D Anthropometric Data

... of the feet, hands and head is applied to the human ...First, the CAESAR models present a severe lack of data for the hands and hence, are not sufficient for the ... Voir le document complet

15

Predicting Human Operator’s Decisions Based on Prospect Theory

Predicting Human Operator’s Decisions Based on Prospect Theory

... presented in positive (i.e. gain) or in negative ...strong and powerful finding (see (Steiger and K¨uhberger, 2018) for a recent meta-analysis) explaining that human beings tend to be ... Voir le document complet

17

Predicting Human Intent for Cooperative Physical Human-Robot Interaction Tasks

Predicting Human Intent for Cooperative Physical Human-Robot Interaction Tasks

... Predicting Human Intent for Cooperative Physical Human-Robot Interaction Tasks Harsh Maithani, Juan Antonio Corrales Ramon and Youcef Mezouar Abstract— In this paper, a robot assistive ... Voir le document complet

7

Multi-scale structural community organisation of the human genome

Multi-scale structural community organisation of the human genome

... as the ones observed for TADs and interval-communities borders ...4 and Additional file 1: Figure S9) [24]. In Human ES cells, master replication initiation zones are enriched in ... Voir le document complet

14

Predicting Human Operator’s Decisions Based on Prospect Theory

Predicting Human Operator’s Decisions Based on Prospect Theory

... Abstract The aim of this work is to predict human operator’s decisions in a specific operational context, such as a cooperative human-robots mission, by approximating her utility function ... Voir le document complet

18

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells

... 42. Bielski CM, Zehir A, Penson AV, Donoghue MTA, Chatila W, Armenia J, Chang MT, Schram AM, Jonsson P, Bandlamudi C, Razavi P, Iyer G, et al. Genome doubling shapes the evolution and prognosis of ... Voir le document complet

28

Discovery and analysis of silencers in Drosophila acting as enhancers in other cellular contexts

Discovery and analysis of silencers in Drosophila acting as enhancers in other cellular contexts

... from the population cages used to collect embryos after the end of cell sorting experiments, to virgin females of the second chromosome balancer line y w; dpp 14 Bl / ...removed and their ... Voir le document complet

195

Myod1 and GR coordinate myofiber-specific transcriptional enhancers

Myod1 and GR coordinate myofiber-specific transcriptional enhancers

... SC9001) and Ctcf- (Sigma-Aldrich, 07–729) immuno- precipitated DNA from skeletal muscle nuclear extracts as described ( 34 ...Ctcf and H3K4me3 or single-end 50 bp reads for the other sequencing ... Voir le document complet

22

Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network

Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network

... transcriptional and chromatin states during the dissociation and isolation procedure, combined with nuclei sorting using FACS, facilitating the isolation of stage- and tissue-specific ... Voir le document complet

10

Characterizing the motogenic response of human keratinocytes to epidermal growth factor and transforming growth factor-alpha

Characterizing the motogenic response of human keratinocytes to epidermal growth factor and transforming growth factor-alpha

... These figures demonstrate, as expected from observations of curves representing population average squared displacement as a function of time (Figures 3.5-3.10), that [r] ... Voir le document complet

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