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[PDF] Top 20 Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction

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Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction

Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction

... While HIV-1 infection with cell-free viruses has been largely documented, cell-to-cell transmission probably represents the dominant mode of infection (23, ...different ... Voir le document complet

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en fr Role of SUMOylation in SAMHD1 activities, a restriction factor of HIV-1 in non-cycling cells Rôle de la sumoylation dans les activités de SAMHD1, un facteur de restriction du VIH-1 dans les cellules non cyclantes

... Figure 1. Inhibition of SUMOylation by ginkgolic acid or anacardic acid renders THP1 cells less resistant to HIV-1 and ...represented in (A) THP1 cells were ... Voir le document complet

179

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells

... degrades SAMHD1. 1 st panel: SAMHD1 protein expression is similar in control DCs (iDC; lane 1), or non- and C- opsonized HIV-1 (HIV-1, HIV-1-C; ... Voir le document complet

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Rôle de la sumoylation dans les activités de SAMHD1, un facteur de restriction du VIH-1 dans les cellules non cyclantes

Rôle de la sumoylation dans les activités de SAMHD1, un facteur de restriction du VIH-1 dans les cellules non cyclantes

... Figure 1. Inhibition of SUMOylation by ginkgolic acid or anacardic acid renders THP1 cells less resistant to HIV-1 and ...represented in (A) THP1 cells were ... Voir le document complet

178

Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae

Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae

... expression of genetically-selected glutathione-S-transferase (GST)-fused di-tryptophan (di-W)-containing peptides inhibited Vpr- mediated growth arrest in ...able to inhibit Vpr biological ... Voir le document complet

11

FOXO1 transcription factor plays a key role in T cell—HIV-1 interaction

FOXO1 transcription factor plays a key role in T cell—HIV-1 interaction

... activity of T cells, affecting all T cell subsets, including naive T ...expression of CD71 and CD98 metabolic markers, increased glucose uptake and greater mitochondrial res- piration after ... Voir le document complet

24

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

... Fig 1. Comparison of the efficacy of VV on non-TNBC or TNBC of different ...canine cells (non TNBC: white circles; TNBC black circles) or ...established cell lines (MCF7: white ... Voir le document complet

21

Ca 2+ -activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion

Ca 2+ -activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion

... DISCUSSION In this paper, we have presented evidence that ezrin cleavage occurs during non-restricted Ca 2+ influx and locally in the phagocytic ...separation of two fluorescent tags on ezrin ... Voir le document complet

10

Analysis of initial cell spreading using mechanistic contact formulations for a deformable cell model.

Analysis of initial cell spreading using mechanistic contact formulations for a deformable cell model.

... governs to a large extent the mechanical interaction between a cell and its ...initial cell spreading is purely adhesion driven, understanding this phenomenon leads to profound insight ... Voir le document complet

15

The skeletal muscle stem cell niche : defining hierarchies based upon the stem cell marker PW1 to identify therapeutic target cells

The skeletal muscle stem cell niche : defining hierarchies based upon the stem cell marker PW1 to identify therapeutic target cells

... Résumé de la thèse 15 musculaires pour de futures réparations ( Olguin and Olwin 2004 ). Ces dix dernières années, d’autres populations cellulaires au potentiel myogénique ont été découvertes. Celles-ci se trouvent dans ... Voir le document complet

222

Cell-cell and cell-medium interactions in the growth of mouse embryonic stem cells

Cell-cell and cell-medium interactions in the growth of mouse embryonic stem cells

... unaware of any efforts at combining the two above types of models so as to better understand the growth of mammalian cells in culture over longer periods of ...time. ... Voir le document complet

130

Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply

Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply

... mediator of the antiviral response, which potently inhibits both early and late phases of HIV ...The SAMHD1 deoxynucleoside triphosphate (dNTP) hydrolase represents the prototype of a ... Voir le document complet

12

Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat

Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat

... analogy to mouse peritoneal macrophages ( 15 ), these probably correspond to a migratory population, and the expression of CCR7 on this population would support that ...population in the ... Voir le document complet

13

Inhibition of HIV-1 replication by cell-penetrating peptides binding rev

Inhibition of HIV-1 replication by cell-penetrating peptides binding rev

... 储 To whom correspondence should be addressed: Laboratoire de Bi- ologie Mole´culaire de la Cellule, UMR5161, Centre National de la Recherche Scientifique, Ecole Normale Supe´rieure de Lyon, 46, Alle´e d’Italie, ... Voir le document complet

8

View of Novel therapeutic targets in sepsis — Triggering receptor expressed on myeloid cells-1: a novel therapeutic target in inflammatory disease

View of Novel therapeutic targets in sepsis — Triggering receptor expressed on myeloid cells-1: a novel therapeutic target in inflammatory disease

... Cancer Les cellules tumorales peuvent utiliser et pervertir le système immunitaire pour leur migration, invasion, angiogenèse, et finalement pour métastaser. Il est maintenant certain que la réponse inflammatoire ... Voir le document complet

7

Anti-HIV potency of T-cell responses elicited by dendritic cell therapeutic vaccination

Anti-HIV potency of T-cell responses elicited by dendritic cell therapeutic vaccination

... five HIV-1 lipopeptide sequences used to load the DALIA vaccine, in particular Gag 253–284 and Pol 325–355 regions, induced strong CD4 + T-cell ...five HIV regions were shown ... Voir le document complet

22

Detecting HIV-1 Tat in Cell Culture Supernatants by ELISA or Western Blot

Detecting HIV-1 Tat in Cell Culture Supernatants by ELISA or Western Blot

... 1. ELISA 96-well plates. 2. Anti-FLAG antibodies and anti-FLAG affinity gel agarose beads. 3. Anti-Tat antibodies. Sensitivity is dependent on the antibody pair used for the assay. A number of companies ... Voir le document complet

12

Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission.

Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission.

... levels HIV-1 infection is associated in vivo with loss of cutane- ous innervation and reduced epidermal nerve fiber density (McCarthy et ...expected to occur upon HIV-1 ... Voir le document complet

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Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy

Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy

... reproduction in any medium, provided the original work is properly ...role in tissue homeostasis and responses to external ...consist of thin-extended membrane protrusions that connect ... Voir le document complet

15

Quantification of the relative importance of CTL, B cell, NK cell, and target cell limitation in the control of primary SIV-infection.

Quantification of the relative importance of CTL, B cell, NK cell, and target cell limitation in the control of primary SIV-infection.

... parameters to vary from one macaque to another through random effects that were assumed to be normally ...used to estimate the parameters. The Bayesian approach to population modelling ... Voir le document complet

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