[PDF] Top 20 Cancer-associated adipocytes promotes breast tumor radioresistance.
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Cancer-associated adipocytes promotes breast tumor radioresistance.
... . Cancer is a tissue-based disease in which malignant cells interact dynamically with multiple normal cell types such as fibro- blasts, adipocytes, infiltrating immune cells and endothelial cells within the ... Voir le document complet
6
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference
... in cancer, and NOD-like receptor signaling pathway (Appendix Fig ...were associated with many biological func- tions; however, the profiles of transcriptomic changes suggested that no other pro-apoptotic ... Voir le document complet
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Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin
... with breast cancer have been shown to promote proliferation, adhesion, and migration of mammary epithelial cells, contrary to the conditioned media from the adipose tissue of non-cancer patients, ... Voir le document complet
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Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin
... with breast cancer have been shown to promote proliferation, adhesion, and migration of mammary epithelial cells, contrary to the conditioned media from the adipose tissue of non-cancer patients, ... Voir le document complet
16
Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression.
... many cancer types including BC (23, 45, ...was associated to a poor outcome, including high proliferation rate and histological grade, as well as increased metastasis and ...PyMT tumor growth and ... Voir le document complet
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miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy
... In breast cancers, this is especially problematic for patients whose tumors are of the TN and basal ...these cancer determi- ...basal breast cancers and is associated with shorter overall sur- ... Voir le document complet
16
ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+T cells by plasmacytoid dendritic cells
... tration, and these cell subsets have been shown to co-localize within primary breast cancer lesions. 5 While pDCs from healthy donors express high levels of the unique ligand of ICOS (ICOSL) upon in vitro ... Voir le document complet
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Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer
... colorectal cancer cells [ 4 ]. Considering that chronic inflammation is associated with an increased risk of cancer incidence and progression [ 65 ], this is a highly clinically relevant ... Voir le document complet
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Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion.
... Discussion Tumor cells cocultivated with mature adipocytes exhibit an enhanced invasive phenotype Human cancer cells with low (ZR ...mature adipocytes (28). After 3 days, tumor cells ... Voir le document complet
13
Asthma-related inflammation promotes lung metastasis of breast cancer cells through CCL11–CCR3 pathway
... Keywords: Lung metastasis, Asthma, Lung inflammation, CCL11–CCR3, Breast cancer © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, ... Voir le document complet
9
Photothermal Depletion of Cancer-Associated Fibroblasts Normalizes Tumor Stiffness in Desmoplastic Cholangiocarcinoma
... tract cancer that is classified based on its location within the bile ducts: intrahepatic, perihilar and distal ...liver cancer and ~3% of all gastrointestinal ...of tumor progression after this ... Voir le document complet
51
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts.
... +/ cancer cells ( Figures S2 A and ...PyMT cancer cells, did not restore TGF- b1 release by PyMT +/ cancer cells to levels observed in PyMT +/+ cancer cells (not ...+/ cancer cells (not ... Voir le document complet
15
Tumor Margin after conservative breast cancer surgery for early disease: an issue or not ?
... upon breast lumpectomy margin assessment as a predictor of residual ...ipsilateral tumor recurrence after breast-con- serving surgery and ...in breast- conserving therapy of early ... Voir le document complet
8
Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer
... MacCallum Cancer Centre, Melbourne, Australia, 62 Cancer Prevention Institute of California, Fremont, California, United States of America, 63 Centre for Genetic Epidemiology, University of Melbourne, ... Voir le document complet
13
Chronic oxidative stress promotes H2 AX protein degradation and enhances chemosensitivity in breast cancer patients
... leads to a persistent accumulation of ROS (Gerald et al, 2004; Laurent et al, 2008; Meixner et al, 2010; Toullec et al, 2010; Cook et al, 2011; Hull et al, 2013; Paneni et al, 2013). As H2AX is a key component of the ... Voir le document complet
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Blood eosinophilic relative count is prognostic for breast cancer and associated with the presence of tumor at diagnosis and at time of relapse
... and acting by means of di fferent mechanisms, as described above. Another possible explanation of the broad separation of the curves is the small sample size in the RLC-low group of only 53 patients, that could allow to ... Voir le document complet
12
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
... Kras G12D/+ ; p21 -/- lung tumors had similar cell cycle arrest and apoptosis profiles in response to cisplatin compared to controls (Supp Fig. S5). Taken together, these data suggest that cisplatin response in vivo is ... Voir le document complet
37
Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials.
... a breast cancer and with no overt metastasis (M0) reported by a clinical and radiological ...from breast cancer surgery to any relapse (local or distant), called “disease-free survival”, and ... Voir le document complet
21
Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
... limited tumor growth in vivo compared to MP6 ...human breast cancer cell lines for which in vitro invasiveness properties have been reported ...in tumor aggressivity whether through ... Voir le document complet
15
Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer
... discovery; they are genetically defined, recently derived (<5 passages), and recapitulate key genetic signatures of KRAS mutant and wild-type human cancers [19]. We validated our in vitro findings in genetically ... Voir le document complet
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