[PDF] Top 20 Bladder cancer and the Notch pathway
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Bladder cancer and the Notch pathway
... Bladder cancer and the Notch pathway Pablo ...Serrano and Antonio Maraver The implication of the Notch pathway in cancer has been known ... Voir le document complet
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Investigating the healthcare pathway through patients’ experience and profiles: implications for breast cancer healthcare providers
... the right one. Moreover, as it was hard to track the whole pathway for each patient, we relied on these sections as a timeline for patients’ comments to point out their experiences through ... Voir le document complet
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Unraveling the Receptor-Ligand Interactions between Bladder Cancer Cells and the Endothelium Using AFM.
... of cancer cells to endothelial cells is a key step in cancer metastasis, therefore identifying the key molecules involved during this process promises to help blocking the metastatic ...in ... Voir le document complet
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Residual tumor micro-foci and overwhelming regulatory T lymphocyte infiltration are the causes of bladder cancer recurrence.
... study, the T lymphocyte infiltrate and the gene expression of tumor-associated antigens (TAA) were analyzed in specimens from tumoral and macroscopically/ histologically free-of-tumor ... Voir le document complet
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The Wnt/beta-catenin pathway in adrenocortical development and cancer
... in the nuclei of neoplastic cells that accumulate in the adrenal cortex of gonadectomized inbred mice, suggesting that the Wnt signaling pathway may participate in gonadectomy-induced ... Voir le document complet
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Statistical approaches for the integration of 'omics' and epidemiological data: an application to bladder cancer
... in the context of ‘omics’ studies ...of the large number of parameters (‘p’) and relatively small number of observations ...is the heterogeneous nature of the ...understand the ... Voir le document complet
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NOTCH pathway inactivation promotes bladder cancer progression
... that the NOTCH pathway could be oncogenic in bladder cancer (37, 38), there is substantial evidence indicating a tumor-suppressive ...of the long arm of chromosome 9q, where ... Voir le document complet
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en fr Regulation of muscle excitability by the potassium channel EGL-23 and the LIN-12/Notch pathway in the nematode Caenorhabditis elegans Régulation de l’excitabilité musculaire par le canal potassique EGL-23 et la voie de signalisation LIN-12/Notch chez le nématode C. elegans
... Étonnamment nous avons découvert que les 6 neurones appartiennent à deux classes différentes : - Les deux neurones latéraux sont des IL2 : IL2L et IL2R Les quatre neurones dorsaux et ve[r] ... Voir le document complet
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The application of signaling networks to cancer metastasis and cellular motility through the EGFR pathway
... This process of trying to characterize the signaling networks and molecular pathways involved in cellular signaling and the mechanical machinery of the cell allows the [r] ... Voir le document complet
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Statistical methods for the integration analysis of -omics data (genomics, epigenomics and transcriptomics): An application to bladder cancer
... investigate the genomic mechanisms involved in complex diseases. During the integration process, many challenges arise such as data heterogeneity, the smaller number of individuals in comparison to ... Voir le document complet
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Noninvasive Urine-Based Tests to Diagnose or Detect Recurrence of Bladder Cancer
... quantify the homozygous deletion of the p16 tumor suppressor ...allows the evaluation of atypical nuclear features; in fact, polysomic cells tend to have large and irregular ...patients ... Voir le document complet
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Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
... showing the number (E–G) of Tg(dusp6:d2EGFP) (E), Topro-3 (F) and sox1a (G) positive parapineal cells in control (blue dots) or mib -/- mutant embryos (orange dots) at 32 hpf, with mean ± ...while ... Voir le document complet
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Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer
... Level and TGAACA Core Motif Mutations Globally, the existence of co-mutations on these different loci (located on different chromosomes) suggests an unknown molecular mechanism of genomic instability ... Voir le document complet
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Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer
... Baseline and subsequent PET were compared for each patient using the EORTC ...with the highest 18F–FDG uptake in as many organs as possible and measured at the follow-up ...(SUVmaxbsa) ... Voir le document complet
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A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification
... for Notch in controlling other signaling pathways activities Examples of vertebrate neuronal lineages in which loss of Notch activity promotes early fates at the expense of late ones are already ... Voir le document complet
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Integrated care pathway for breast cancer: a relational and geographical approach
... ICPs The initial categorization of breast cancer care pathways we propose here allows us to identify the role of geographic mapping in the development of integrated cancer ...on ... Voir le document complet
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Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old Wistar rats
... : The aged-related decrease in skeletal muscle regeneration capacity is a contributing factor to sarcopenia ...[1]. The decreased activity of the Notch signalling pathway with aging ... Voir le document complet
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Population model of bladder motion and deformation based on dominant eigenmodes and mixed-effects models in prostate cancer radiotherapy
... by the required num- ber of CT scans per patient for training the ...at the planning treatment for a typical patient, and on-treatment CTs/CBCTs are seldom available during ...learned ... Voir le document complet
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Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation
... assess bladder inflammation and related pain ( Lantéri-Minet et ...stimulation and, as in our study, found increased sensitivity in the lower abdominal ...is the first time that ... Voir le document complet
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Serum Matrix Metalloproteinase-7 is an independent prognostic biomarker in advanced bladder cancer
... median and range were computed. To investigate their associations with the clinical, pathological and biological parameters, univariate statistical analyses were performed using the Pearson’s ... Voir le document complet
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