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[PDF] Top 20 Biomarkers of prognosis and efficacy of treatment

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Biomarkers of prognosis and efficacy of treatment

Biomarkers of prognosis and efficacy of treatment

... Process of soluble biomarkers development SURROGATE Qualification Validation Discovery Brain/OMICS technics Analytical performance of assay Assessing clinical value.. OA Biomarkers lymp[r] ... Voir le document complet

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Biomarkers of prognosis and efficacy of treatment in OA

Biomarkers of prognosis and efficacy of treatment in OA

... identification of 16 biochemical markers investigating cartilage matrix ...CIIM) and synthesis (PIIANP, ...(CS846) and ARGS-aggrecan fragment investigate proteoglycans ...(Fib3-1 and Fib3-2) ... Voir le document complet

1

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

... activation of the DNA-dependent protein kinase (DNA-PK) ( 20 ...phosphorylation of H2AX and other markers such as RPA32, CHK2 and HSP90 ( 20 , 30 ), prevents detection of the ... Voir le document complet

11

Biomarkers of prognosis and efficacy of reatment

Biomarkers of prognosis and efficacy of reatment

... • Indicative of treatment efficacy and for which the magnitude of the change is considered pertinent to the response. E fficacy of treatment[r] ... Voir le document complet

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Circular RNAs and RNA Splice Variants as Biomarkers for Prognosis and Therapeutic Response in the Liquid Biopsies of Lung Cancer Patients

Circular RNAs and RNA Splice Variants as Biomarkers for Prognosis and Therapeutic Response in the Liquid Biopsies of Lung Cancer Patients

... up-regulation of 2,909 circRNAs and down-regulation of 8,372 circRNAs in taxol- resistant A549 lung adenocarcinoma cells compared to parental ...VEGFR, and rho GTPase signaling or degradation ... Voir le document complet

16

Macrofilaricidal Efficacy of Repeated Doses of Ivermectin for the Treatment of River Blindness

Macrofilaricidal Efficacy of Repeated Doses of Ivermectin for the Treatment of River Blindness

... Design and Data Collection The data were collected between 1994 and 1998 during a clinical trial undertaken in a hyperendemic onchocerciasis focus with no history of ivermectin distribution or vector ... Voir le document complet

10

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer

... men and occurs at a median age of 73 years old [ 1 ...rates of 3.2 and 0.9, respect- ively [ 2 ]. More than half of cases are occurring in the most developed areas including Europe ... Voir le document complet

10

A comprehensive review of genomic landscape, biomarkers and treatment sequencing in castration-resistant prostate cancer

A comprehensive review of genomic landscape, biomarkers and treatment sequencing in castration-resistant prostate cancer

... finding of five or more circulating tumor cells (CTCs) prior to the initiation of cytotoxic chemotherapy is associated with inferior OS while the decline of CTCs count below five has been ... Voir le document complet

37

Efficacy and Safety of Sofosbuvir plus Daclatasvir for Treatment of HCV-associated Cryoglobulinemia Vasculitis.

Efficacy and Safety of Sofosbuvir plus Daclatasvir for Treatment of HCV-associated Cryoglobulinemia Vasculitis.

... 7211, and Inflammation- Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; 2 INSERM, UMR_S 959, F-75013, Paris, France; 3 CNRS, FRE3632, F-75005, Paris, France; 4 AP-HP, Groupe Hospitalier ... Voir le document complet

27

The Identification of Novel Biomarkers Is Required to Improve Adult SMA Patient Stratification, Diagnosis and Treatment

The Identification of Novel Biomarkers Is Required to Improve Adult SMA Patient Stratification, Diagnosis and Treatment

... Conclusions and Discussion The complexity of the SMA phenotypes, and the discrepancies between patients’ genotype (as per current definition) and phenotype, have fostered the search for ... Voir le document complet

24

Validation of biomarkers of food intake-critical assessment of candidate biomarkers

Validation of biomarkers of food intake-critical assessment of candidate biomarkers

... performance of the BFI analysis ...standards of analytical quality and what is sufficient may depend heavily on the intended use, ...conditions of the untargeted analysis ...use and ... Voir le document complet

15

Antiviral therapy in hemodialyzed HCV patients: efficacy, tolerance and treatment strategy

Antiviral therapy in hemodialyzed HCV patients: efficacy, tolerance and treatment strategy

... p=0.007) and similar concentrations ...IFN and an adapted schedule of ribavirin are effective in ESRD ...start of treatment provides better hematological ...dosage of ribavirin ... Voir le document complet

27

Seminoma arising in corrected and uncorrected inguinal cryptorchidism: treatment and prognosis in 66 patients

Seminoma arising in corrected and uncorrected inguinal cryptorchidism: treatment and prognosis in 66 patients

... Purpose: The purpose of this study was to analyze prognosis and treatment results for seminoma arising in corrected and uncorrected inguinal cryptorchidism (SCIC and SUIC).. Methods[r] ... Voir le document complet

8

Efficacy of anti-IL-1 treatment in familial Mediterranean fever: a systematic review of the literature.

Efficacy of anti-IL-1 treatment in familial Mediterranean fever: a systematic review of the literature.

... homolog of the human IL-1 receptor that com- petitively inhibits binding of IL-1-alpha and -beta to its ...consisting of the extracellular portions of the human IL-1 receptor and ... Voir le document complet

6

View of Neurological prognosis

View of Neurological prognosis

... Patients and methods: We prospectively studied a cohort of trau‑ matic coma patients and compared overnight resting‑state EEG to standardized clinical ...withdrawal and 1 week after), ... Voir le document complet

5

View of Haemodynamics — prognosis

View of Haemodynamics — prognosis

... inclusion des patients hospitalisés en réanimation entre 2002 et 2011 pour la prise en charge d’une embolie pulmonaire ou dont le séjour en réanimation s’est compliqué d’une ep. Les ré[r] ... Voir le document complet

5

Prognosis and ICU outcome of systemic vasculitis

Prognosis and ICU outcome of systemic vasculitis

... outcome and prognosis of pa- tients with vasculitides admitted to ICU have been pub- ...Most of the reports included systemic rheumatic diseases like connectivitis, rheumatoïd polyarthritis, ... Voir le document complet

7

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Benin

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Benin

... total of 30 cases of LTF were observed from day 21 onwards, giving a rate of re-infection of ...AL treatment was observed in Zam- bia with 37 % in Chongwe [ 29 ], ...], and more ... Voir le document complet

9

Myeloid-Derived Suppressor Cells in Hematologic Diseases: Promising Biomarkers and Treatment Targets

Myeloid-Derived Suppressor Cells in Hematologic Diseases: Promising Biomarkers and Treatment Targets

... biology of MDSCs, a number of issues related to the generation, expansion, and circulation of these cells and their precise role in the microenvi- ronment of BM and ... Voir le document complet

13

Open Access to the Resource of Antibiotic Treatment Efficacy Subject to Bacterial Resistance

Open Access to the Resource of Antibiotic Treatment Efficacy Subject to Bacterial Resistance

... combination of the economic model with a biological model of disease transmission allows us to capture the evo- lution of bacterial resistance (a non-desirable bio-economic ...solution of the ... Voir le document complet

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