[PDF] Top 20 Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles
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Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles
... 2 Using siRNA therapeutics to treat hematologic malignancies has been unsuccessful because blood cancer cells exhibit remarkable resistance to standard methods of ... Voir le document complet
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A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non–Small Cell Lung Cancer
... control of size, combination therapeutics with high loading capacity, staged cargo release, enhanced stability in vivo, and tunable surfaces for ...Because of the modular nature of LbL ... Voir le document complet
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In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanoparticles for siRNA Delivery
... degree of specificity for targeting selected ...on cells in vitro, but in vivo siRNA therapy remains a challenge for solid tumor treatment as siRNAs display difficulty ... Voir le document complet
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A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy
... conventional siRNA concen- tration used for in vivo siRNA delivery in mice ...Targeted siRNA/AD/E 16 G 6 RGDK delivery system (A, B) accumulates more e fficiently in tumor ... Voir le document complet
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Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route
... imaging. In vivo imaging was conducted at Optimal (Grenoble, France), a core facility for small animal optical ...weeks of tumor development, mice received an i.p. injection of 150 µg/g ... Voir le document complet
11
Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells
... ability of host cells to infiltrate disease sites and act as self-directed vectors for therapeutics is being explored in a number of contexts, most commonly employing phagocytic ... Voir le document complet
22
Additive Layer Manufacturing using Metal Deposition
... technique to generate Fe/Al walls by fusing simulateously an AISI304 stainless steel wire and a A4043 Al-Si alloy wire on a low carbon steel ...optimization of the process, and especially of ... Voir le document complet
4
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature
... uptake in lung endothelial cells as shown by flow ...tagged siRNA and injected into the tail veins of ...Endothelial cells were identified as CD31+, CD45−, and EPCAM−, epithelial ... Voir le document complet
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In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer
... comparable to proliferating tumor cells, and to evaluate whether we could take advantage of decorin selective oncolytic property, we analyzed the in vitro decorin effect on A549 human ... Voir le document complet
42
A Cluster Approach for the modelling of the layer-by-layer growth of SiC polytypes
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet
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2014 — Conception d'un revêtement bioactif pour implant cardiovasculaire par la méthode du layer-by-layer
... menés in vitro sur des cellules A7R5, une lignée de cellules musculaires lisses (VSMC) provenant de l’aorte de rat (A7r5 from rat (Rattus norvegicus) aorta, ATCC, Manassas, ... Voir le document complet
145
Examination of HER3 targeting in cancer using monoclonal antibodies
... | cancer therapy | HER3 | signal transduction | tyrosine kinase G rowth factors and their plasma-membrane–embedded re- ceptors regulate cellular proliferation and migration during both embryogenesis and ... Voir le document complet
7
Bénard instabilities in a binary-liquid layer evaporating into an inert gas
... evaporation of the solvent (water) into the model (which here has been done just in the framework of the approximate solution for the reference profile, as described above, and the Pearson-like ... Voir le document complet
50
Formation of convective cells in the scrape-off layer of the CASTOR tokamak
... control of the particle and heat transport at the tokamak edge is of primary importance for design of future large-scale ...properties of the plasma inside and outside the last closed magnetic ... Voir le document complet
8
Plasma hydrogenated cationic detonation nanodiamonds efficiently deliver to human cells in culture functional siRNA targeting the Ewing sarcoma junction oncogene
... 2.5. siRNA delivery to cells: confocal microscopy and fluorescence ...described in Ref. [17], equipped with single photon counting module capable of detecting single nitrogen color ... Voir le document complet
17
Few layer graphene as a template for Fe-based 2D nanoparticles
... spectra of iron oxide over FLG before and after µ-waves treatment, c) and d) corresponding TGA and Raman spectra The presented examples show that not only the flattening of metal occurs but also graphene ... Voir le document complet
13
Loading of dendrimer nanoparticles into layer-by-layer assembled Poly(diallyl dimethyl ammonium) chloride-(Poly(acrylic acid))n Multilayer Films : Particle Electrokinetics, Film Structure Dynamics and Elasticity
... present in the donut structures since no O-H stretching mode could be detected above 3200 cm -1 ...evidenced in Figures 6C-6D and Figures 6E-6F for the film domains outside and inside the donut-ring ... Voir le document complet
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Targeting breast cancer stem cells: fishing season open!
... developed to design the best therapeutic strategies targeting ...on targeting key pathways regulating CSC survival, differentiation and ...involved in self-renewal of embryonic and ... Voir le document complet
9
Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells
... Edited by Richard Heller, Old Dominion University, Norfolk, VA, and accepted by the Editorial Board May 16, 2011 (received for review March 3, 2011) The RNA interference-mediated gene silencing approach is ... Voir le document complet
6
Resveratrol reverses the Warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells
... according to protein content. Protein analysis. Cells were treated with 10 µM resveratrol for 48 ...extracted in RIPA lysis buffer (1X PBS, 1% NP40, ...The cells were extracted on ice for 30 ... Voir le document complet
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