Top PDF Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis
Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis
... deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private research ...
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Genetic variations in bile acid homeostasis are not overrepresented in alcoholic cirrhosis compared to patients with heavy alcohol abuse and absent liver disease
... progression in ALD, at least in the differentiation from other forms of chronic liver ...polymorphisms in ABCB11 encoding for BSEP have been identified as risk factors for intrahepatic cholestasis of ...
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Bile acid-receptor TGR5 deficiency worsens liver injury in alcohol-fed mice by inducing intestinal microbiota dysbiosis
... steatosis and in fl ammation than in WT ...WT and TGR5-KO alcohol-fed mice showed that TGR5 de fi ciency did not increase the pro- in fl ammatory phenotype of liver macrophages but ...
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Chemotherapy-driven dysbiosis in the intestinal microbiome
... Amino acid metabolism, carbohydrate metabolism, nucleotide metabolism, energy metabolism, and metabolism of cofactors and vitamins categories were decreased in samples collected after che- ...
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Title: Bile acid alterations in non-alcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes: what do the human studies tell?
... BAs in metabolic and cellular homeostasis render BAs attractive candidates as players in the pathophysiology of ...resistance and T2D, it is difficult to establish clear and ...
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Bile acid metabolism and the pathogenesis of type 2 diabetes.
... the bile acid pool by intestinal sequestration has been shown to improve insulin resistance in rat models of diabetes by promoting the secretion of GLP1 from intestinal L-cells [ 18 19 ...
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Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD Short title: Bile acids in meta-inflammatory disorders
... glucose homeostasis, and colesevelam is a FDA- approved oral antidiabetic ...FXR in intestinal L-cells, enterocytes and hepatocytes, increasing GLP-1 synthesis and secretion, ...
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The effect of exercise training on cholesterol and bile acid metabolism in ovariectomized rats
... disease and atherosclerosis, which constitute the largest cause of mortality in developed countries (Mozaffarian et ...age in women, with a noticeable increase after menopause (Sharp et ...
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Running head: Heat affects cholesterol and bile acid alterations in cholesterol and bile acids metabolism in large white pigs during short-term heat exposure
... exhibited in short and long term heat ...intense in the first three days’ response to environmental changes and seems to decline in the long-term stage to adapt to stress [ 26 , 48 ...
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Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance
... G-Protein-Coupled Bile Acid Receptor 1 (GP-BAR1), also known as Takeda G- protein-coupled receptor 5 (TGR5) is a G Protein Coupled Receptor sensitive to bile ...role in various organs, tissues ...
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Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
... 1,2,3,4 Bile acids (BAs) are molecules with endocrine activities controlling several physiological functions such as immunity, glucose homeostasis, testicular physiology and male ...FXRα in ...
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A bile acid transporter as a candidate receptor for hepatitis B and D virus entry.
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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View of Acute alcoholic hepatitis: management in 2011
... toxicity and an inflammatory ...encephalopathy, and/or tender liver) and laboratory tests (showing elevated aspartate aminotransferase > 2N with an aspartate aminotransferase-to-alanine ...
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Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters
... finding in this study was the increase in plasma bile acid concentrations in CRF, which is consistent with previous clinical reports by Jimenez et ...vated bile acid ...
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View of Severe acute alcoholic hepatitis
... microbiote intestinal (MI) ou flore intestinale est composé de 10 14 micro-organismes représentant dix fois plus que le nombre de cellules de l ’organisme ...
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Intestinal dysbiosis in Inflammatory Bowel Disease associated with primary immunodeficiency.
... IBD in remission were recruited at the Gastroenterology Department of the Saint Antoine Hospital (Paris, France) and provided informed consent (local ethics committee: Comité de Protection des Personnes ...
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TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload
... least in part why TGR5-KO mice were more prone to BA-induced parenchymal ...function and/or BA pool composition might also contribute to this phenotype. In the present study, we first observed that CC ...
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Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis
... linking alcoholic liver disease with mitochondrial dysfunction, 28 we provided evidence that such a deficiency is a key feature of severe ...Indeed, in this severe form of alcohol-induced liver injury, the ...
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The role of dietary sugars in intestinal homeostasis and microbiota composition
... 5. Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K., Grarup, N., Jørgensen, T., Brandslund, I., ...
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View of Non Alcoholic Fatty Liver Disease and Non Alcoholic Steato-Hepatitis are Multisystemic Diseases: Review for Intensivists
... Efficacy and Safety of Elafi- branor Versus Placebo in Patients With Nonalcoholic Stea- tohepatitis [NASH] [RESOLVE-IT] ; NCT02704403) et per- mettra d ’asseoir ou non ces résultats qui sont discutés du ...
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