[PDF] Top 20 Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.

... influence of insulin resistance and type 2 diabetes on the regulation of apelin and APJ in AT and skeletal muscle both in ... Voir le document complet

... keletal muscle insulin resistance is a strong risk factor of type 2 diabetes and cardiovascular dis- eases ...Dysfunctional adipose tissue can lead to lipid oversupply ... Voir le document complet

... accumulating in muscle could play a causative role in IR, via activation of PKC and serine/threonine kinases that inhibit insulin signaling ...metabolism in skeletal ... Voir le document complet

... involved in the control of energy metabolism. In the hypothalamus, chronic exposure to high levels of apelin is associated with an increase in hepatic glucose production, ... Voir le document complet

... form of AMPK have blunted response to energy deprivation by β - GPA feeding, showing that AMPK is necessary for mitochondrial biogenesis in response to metabolic stress ...phosphorylated and ... Voir le document complet

... effects of the mixture and the effecs of PCB118 or PCB153 alone, even with genes involved in xenobiotic metabolism, where we have observed the stron- gest modifications of gene ... Voir le document complet

... Abundance of SFAs is harmful to normal cell function (Borradai1e, Han et al. 2006) and higher desaturation rates and SCD 1 expression was shown to protect against such [r] ... Voir le document complet

... used in obesity management. Most of these studies used mixtures of carotenoids and vitamins in a natural matrix, such as fruit juices or plant extracts (reviewed by Bonet et ... Voir le document complet

... affecting in priority tissues of mesenchymal origin. The story began in 1999 by the discovery by ...working in the group of K. Schwartz in Paris that this gene was responsible ... Voir le document complet

... 2.2. In vivo muscle protein synthesis MPS was measured with the SUnSET method as previously described by Goodman et ...[23] and previously used by us [22,24] ...method in ex vivo plantaris ... Voir le document complet

... Properties of Fast- and Slow-Twitch Muscles EDL and SOL muscle force properties were analyzed using in situ muscle contraction measurements as described previously ...Succinctly, ... Voir le document complet

... pharmacokinetics of ganciclovir differ between adult and newborn mice, with a higher peak plasma concentration and slower elimination in newborn ...animals. In addition, ... Voir le document complet

... parameters of the metabolic syndrome and delay the onset of diabetic complications ...player in the homeostatic control of whole body ...methylome and microRNA arrays, ... Voir le document complet

... established in 2004 in Managua, Nicaragua ...II of Managua, a low- to middle-income area with a population of approximately ...living in District II were enrolled, and new ... Voir le document complet

... Mitsugumins In addition to the proteins mentioned above, which are involved in the biogenesis of T-tubules, other proteins are implicated in the maturation of SR terminal cister- nae, ... Voir le document complet

... prevention and treatment of Type 2 Diabetes. The aim of this work was to compare the effects of a traditional Moderate Intensity Continuous Training (MICT) with a High Intensity ... Voir le document complet

... Skeletal muscle provides a suitable model for such studies because the molecular pathways regulating differentiation and growth arrest have been ...identified. Muscle formation relies on a ... Voir le document complet

... Experiment and Histological Analysis Rag2 IL2rb mice were anesthetized with an intra-peritoneal injec- tion ...weight) of a solution containing 100 mg/mL ketamine (Merial, Lyon, France) and 20 ... Voir le document complet

... of biological replicates for each ...reproducibility of expression across samples, with 1249 of them having an FPKM-UQ higher than ...0.1 in at least 10 of the 16 samples in the ... Voir le document complet

... abundant in human and mouse mucosae, particularly in the gut [ 2 ], and are largely resident, because only 20% of green Kaede cells were recovered from light-exposed LN a week ... Voir le document complet