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[PDF] Top 20 AMP-activated protein kinase and metabolic control.

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AMP-activated protein kinase and metabolic control.

AMP-activated protein kinase and metabolic control.

... T2D and insulin ...prevent and control ...regular and moderate regimens of physical activity. The multiple metabolic adaptations that occur in response to physical activity can improve ... Voir le document complet

15

AMP-activated protein kinase alpha2 deficiency affects cardiac cardiolipin homeostasis and mitochondrial function.

AMP-activated protein kinase alpha2 deficiency affects cardiac cardiolipin homeostasis and mitochondrial function.

... INTRODUCTION AMP-activated protein kinase (AMPK) signaling pathway plays an important role in controlling energy homeostasis at the whole body level by responding to hormonal or nutrient ... Voir le document complet

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AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of ras-transformed fibroblasts

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of ras-transformed fibroblasts

... MCT1 and MCT4, to maintain pHi and energy ...glycolysis and tumour growth without affecting ATP ...5’-AMP-activated protein kinase (AMPK) in energy homeostasis, we ... Voir le document complet

16

Tumor suppressor fumarate hydratase is phosphorylated and regulated by AMP-activated protein kinase

Tumor suppressor fumarate hydratase is phosphorylated and regulated by AMP-activated protein kinase

... equally. AMP-activated protein kinase (AMPK) is a central cellular signaling hub involved in energy homeostasis, growth and ...The kinase is considered as a promising target for ... Voir le document complet

3

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en fr Role of neuronal AMP-activated protein kinase (AMPK) deregulation on tau pathology, synaptic integrity and energy metabolism : relevance for Alzheimer’s disease Rôle de la dérégulation neuronale de la protéine kinase activée par l’AMP (AMPK) dans la pathologie tau, l’intégrité des synapses et le métabolisme énergétique : relevance pour la maladie d’Alzheimer

... neuronal AMP-activated protein kinase (AMPK) deregulation on tau pathology, synaptic integrity and energy metabolism: Relevance for Alzheimer’s disease Alzheimer's disease (AD) is a ... Voir le document complet

280

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en fr AMP-activated protein kinase : Screening for novel membrane substrates and creatine kinase phosphorylation linked to specific subcellular compartment La protéine kinase activée par AMP : Criblage de nouveaux substrats membranaires et phosphorylation de la créatine kinase liée à une compartimentation subcellulaire

... synthesis and translocation (Mayinger and Meyer, ...to and/or function at the ER under condition of energy stress and thus its contribution to Ca 2+ ...proteins and MCK inhibition ... Voir le document complet

132

AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice.

AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice.

... level and peroxynitrite content in lung homogenates Animals were euthanized and perfused with cold saline via the ...removed and homo- genized in 1 ml of PBS containing complete protease inhibitor ... Voir le document complet

9

AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3beta (GSK-3beta) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.

AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3beta (GSK-3beta) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.

... 2010, and in revised form, February 21, 2011 Published, JBC Papers in Press, March 7, 2011, DOI ...**, and Michael ...Cellular and Molecular Physiology, and ¶ Genetics and the **Section ... Voir le document complet

12

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.

... growth and sensitivity to nutrient signals ...growth and proliferation requirement (9, ...higher protein synthesis rate and ultimately to increased muscle cell ...4A and 4B) and ... Voir le document complet

22

AMP-activated protein kinase and autophagy.

AMP-activated protein kinase and autophagy.

... it has been shown that the activation of AMPK by low-oxygen conditions is involved to maintain energy homeostasis in a hypoxic environment. 20 Thus, the activation of AMPK, together with HIF (hypoxic-inducible ... Voir le document complet

4

Place de l'AMP-activated protein kinase dans le preconditionnement ischemique renal.

Place de l'AMP-activated protein kinase dans le preconditionnement ischemique renal.

... interruption and recovery of renal circulation, as observed during ...structure and function in I/R ...monophosphate-activated protein kinase ...vitro and in vivo data about the ... Voir le document complet

8

AMP-activated protein kinase controls liposaccharide-induced hyperpermeability

AMP-activated protein kinase controls liposaccharide-induced hyperpermeability

... evaluate and compare the microcirculatory perfusion of potentially available parts of the body, such as sublingual mucosa, conjunctiva of the eye, mucosa of jejunum and rectum, at the same time points ... Voir le document complet

189

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells

... scaffold protein ezrin-radixin-moesin- binding phosphoprotein 50 (EBP50) A yeast two-hybrid screen of human liver cDNA identified EBP50, a PDZ protein highly expressed in the liver, as a binding ... Voir le document complet

47

Adenosine A2A receptor blockade prevents synaptotoxicity and memory disfunction caused by beta-amyloid via p38 mitogen-activated protein kinase pathway

Adenosine A2A receptor blockade prevents synaptotoxicity and memory disfunction caused by beta-amyloid via p38 mitogen-activated protein kinase pathway

... totoxicity and memory dysfunction is fur- ther strengthened by the key observation of the present study ...toxicity and memory impairment caused by A␤ ...2007), and their blockade prevents synap- ... Voir le document complet

11

The FRK1 mitogen-activated protein kinase kinase kinase (MAPKKK) from Solanum chacoense is involved in embryo sac and pollen development

The FRK1 mitogen-activated protein kinase kinase kinase (MAPKKK) from Solanum chacoense is involved in embryo sac and pollen development

... cytoplasm and the nucleus ( ...GFP control). In con- trast, luorescence of the ScFRK1–GFP fusion protein was restricted to the nuclei and co-localized with the 4′,6-diamid- ino-2-phenylindole ... Voir le document complet

12

AMP-Activated Protein Kinase Signalling

AMP-Activated Protein Kinase Signalling

... structures and provide expert insight into the molecular mechanisms of kinase activity modulation by adenine nucleotides [ 1 ...of AMP changes the AMPK’s conformational landscape, providing direct ... Voir le document complet

6

Protein kinase D increases maximal Ca 2+ -activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser 315

Protein kinase D increases maximal Ca 2+ -activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser 315

... sensitivity and maximal tension of ...(TnI), and p-myosin light chain-2 (MLC2) in mouse myofilaments incubated for 30 min with full-length active ...loading control. B: the relationship between Ca 2! ... Voir le document complet

10

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en fr Interactomics of key kinases in energy metabolism : Characterizing interactions of AMP-activated protein kinase & B-type creatine kinase Ineractomique d'enzymes clef du métabolisme énergétique : Charactérisation d'interactions de la protéine kinase activée par AMP et de la creatine kinase cytosolique du cerveau (B-type)

... VAMP3 and the close family member VAMP2 was independently observed in two different Y2H systems ...cyto-Y2H and Split-Trp Y2H), and VAMP2 enriched with synaptic vesicles was co- immunoprecipitated ... Voir le document complet

236

Activation of AMP kinase alpha1 subunit induces aortic vasorelaxation in mice.: Vasorelaxation associated with AMP kinase a1 subunit

Activation of AMP kinase alpha1 subunit induces aortic vasorelaxation in mice.: Vasorelaxation associated with AMP kinase a1 subunit

... The AMP-dependent protein kinase (AMPK) is a serine/threonine kinase that is activated by conditions that increase the AMP-to-ATP ratio, such as exercise and ... Voir le document complet

26

Studies of the role of MAP kinase-activated protein kinase-5 (MK5) in reactive and reparative fibrosis in the murine heart

Studies of the role of MAP kinase-activated protein kinase-5 (MK5) in reactive and reparative fibrosis in the murine heart

... synthesis and/or stability. TGF-β is a cytokine, expressed in both myocytes and fibroblasts, which acts upon receptors that are also expressed in both cell ...remodeling and hypertrophy (40) whereas ... Voir le document complet

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