[PDF] Top 20 Amino acids and mTORC1: from lysosomes to disease
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Amino acids and mTORC1: from lysosomes to disease
... chronic disease that is generally hastened by long-term overfeeding and insulin resistance, two conditions related to excess mTORC1 ...glucose and amino acids in the blood ... Voir le document complet
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The role of amino acids in liver protein metabolism under a high protein diet : identification of amino acids signal and associated transduction pathways
... activate mTORC1 kinase activity in vitro (Sancak et ...parallel to the Rag GTPases because a constitutively active Rheb allele was enough to promote cell growth in the absence of Rag GTPases, while a ... Voir le document complet
190
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
... Parkinson Disease Genomics et ...140 amino acids mainly localized to presynaptic ...remains to be fully understood, several studies have implicated its capacity to interact ... Voir le document complet
8
PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes
... mRuby2 and the PI(3)P-binding protein 2xFYVE-GFP, as markers for endolysosomes and stage I melanosomes, ...correspond to early endosomes in pigment cells and contain mature PMEL and ... Voir le document complet
51
Engineering a thermostable fungal GH10 xylanase, importance of N-terminal amino acids
... N- and C-terminal sequences of 4S1 and three bacterial GH10 xylanases from Bacillus halodurans S7 (BHX), Bacillus firmus (BFX) and Bacillus ...obtained from database of Protein Data ... Voir le document complet
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Biotic and abiotic transformation of amino acids in cloud water: Experimental studies and atmospheric implications
... 2) and photo- chemical (Eq. 3) rates as derived from the experiments, and the kinetic loss rates based on chemical kinetics ...18 amino acids. For some of the acids (ALA, GLU, ... Voir le document complet
14
Biotic and abiotic transformation of amino acids in cloud water: experimental studies and atmospheric implications
... sulfur and organic nitrogen ...assigned to CHO, CHNO, CHSO, and CHNSO (Bianco et ...fraction to the total nitrogen in cloud water (18 %) (Hill et al., 2007) and in aerosol particles (7 ... Voir le document complet
15
Hyperuricemia and Hypertension, Coronary Artery Disease, Kidney Disease: From Concept to Practice
... far from simple and comes from both experimental and clinical ...according to whether its effects occur extracellularly or ...cells from oxidative stress, and when it ... Voir le document complet
15
A new diagram for amino acids: User study comparing rainbow boxes to Venn/Euler diagram
... of amino acid properties. However, Euler diagrams are not always easy to read for students, and they are complex to produce when the number of sets is above ...for amino acids, ... Voir le document complet
8
Branched-chain amino acids do not improve muscle recovery from resistance exercise in untrained young adults.
... precluding to determine whether the effects of BCAA supplementation were independent of the daily protein ...blood amino acids levels to confirm the absorption of ...mTOR, and p70S6 k); ... Voir le document complet
23
The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids
... similar to polyglu- tamylation, performed by members of the TTLL family (Rogowski et ...proteins, and because M20 peptidases are not found in the mammalian genome, other candidates were considered as ... Voir le document complet
25
Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotype.: Fatty acids and ApoE genotype
... ApoE and fatty acids Whereas cholesterol in the brain is produced and regulated endogenously [ 55 ] , the fatty acid content of neuronal membranes can be modulated by dietary intake and ApoE ... Voir le document complet
15
Chiral separation of racemic amino acids through membranes derived from modified polysulfone having perillaldehyde moiety as a side group
... This publication could be one of several versions: author’s original, accepted manuscript or the publisher’s version. / La version de cette publication peut être l’une des suivantes : la version prépublication de ... Voir le document complet
7
Accelerated Microfluidic Native Chemical Ligation at Difficult Amino Acids Towards Cyclic Peptides
... versatility and fast time-to-market • In phase with the actual transitioning toward flow and microfluidic technologies for pharmaceutical production, the combination of microfluidics and ... Voir le document complet
1
Isonitrile-based multicomponent synthesis of β-amino boronic acids as β-lactamase inhibitors
... new and more potent β-lactamase ...Materials and Methods ...due to a score ...allowed, and finally, the “simulation interactions diagram” tool of Maestro permitted us to gain insights ... Voir le document complet
21
Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides
... dedicated to their production, in phase with the actual transitioning toward continuous flow and microfluidic technologies for pharmaceutical pro- ...fast and ef ficient peptide cyclization using native ... Voir le document complet
12
Chemical and physical effects of super-voltage cathode rays on amino acids in foods and in aqueous solutions
... When the ammonia yield obtained on irradiation of 0.1 M solution of histidine monohydrochloride is plotted against the dosage, a curve shown in Figure XXIII is obtain[r] ... Voir le document complet
258
Nitrogen and carbon isotope values of individual amino acids: a tool to study foraging ecology of penguins in the Southern Ocean
... species to test the efficacy of amino acid δ 15 N and δ 13 C analyses to determine the ecological niches of seabirds as their food habits and foraging habitats are well documented ... Voir le document complet
40
Introducing sequential aza--amino acids units induces repeated β--turns and helical conformations in peptides
... described to stabilize isolated α-‐turn conformations and the strategy is essentially to replace the i, i+4 hydrogen bond by a covalent ...diaza-‐amino acids units might resolve a ... Voir le document complet
71
Species-Specific Contribution of the Four C-Terminal Amino Acids of Influenza A Virus NS1 Protein to Virulence
... Altogether, these results indicate that the C-terminal domain of NS1 modulates viral growth in a host-specific way: in the context of an H7N1 avian influenza virus strain, the typical avia[r] ... Voir le document complet
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