[PDF] Top 20 Acute myeloblastic leukemia in adult patients: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

... cytogenetics and molecular genetics. risk assessment Risk assessment in AML includes the patient’s age, the initial leukocyte count, the AML subtype, karyotype data and selected molecular ... Voir le document complet

... cytogenetics and molecular genetics. risk assessment Risk assessment in AML includes the patient’s age, the initial leukocyte count, the AML subtype, karyotype data and selected molecular ... Voir le document complet

... through clinical examination, serial peripheral blood counts and bone marrow ...monitor for early marrow response or leukemic blast ...<5% in bone marrow smears and morphologically ... Voir le document complet

... treated. In addition to clinical examination, additional techniques recommended are computed tomography (CT) scans of the chest and the abdomen, and radiological imaging of teeth and ... Voir le document complet

... non-intensive treatment of MDS and AML Patients with significant co-morbidity, the elderly, thus including many patients with MDS, are often not eligible for intensive treatment, ... Voir le document complet

... 2. Grimwade D, Walker H, Oliver F et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML 10 trial. Blood 1998; 92: 2322–2333. 3. Appelbaum FR, ... Voir le document complet

... counts and bone marrow aspi- ...monitor for early marrow response or leukemic blast ...hematopoiesis and blast levels <5% at evaluation of bone marrow smears ... Voir le document complet

... policies for follow-up of surgically treated patients with localized ...or in the ...size and tumor site may help in choosing the routine follow-up ... Voir le document complet

... policies for follow-up of surgically treated patients with localized ...size and tumor site may help in choosing the routine follow-up ...risk patients ... Voir le document complet

... carcinoma in situ (DCIS) ...of patients benefit from adjuvant radiation as well as from adjuvant tamoxifen [I, ...tamoxifen for DCIS reduces the recurrence rate of in situ and of ... Voir le document complet

... tumors in the tissue removed, the maximum diameter of the largest tumor (T), histologic type and grade of the tumor, evaluation of the resection margins including the minimum margin in millimetres ... Voir le document complet

... selected patients by experienced thoracic surgeons in the context of a multidisciplinary team and preferably as part of a clinical trial [III, ...wall and adequate cardiopulmonary ... Voir le document complet

... ubiquitous in their site of origin, and are often treated with multimodality ...Multidisciplinary treatment planning is therefore mandatory in all cases (involving pathologists, radiologists, ... Voir le document complet

... I and IIa Surgery should involve total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, random peritoneal biopsies including the paracolic gutters and at least pelvic/ para-aortic lymph ... Voir le document complet

... Minimum Clinical Recommendations for diagnosis, treatment and follow-up of pancreatic cancer Incidence ...incidence and mortality of pancreatic cancer ... Voir le document complet

... prognosis. In particular the subgroup of patients with a deletion on chromosome 1p and 19q seem to have a longer survival and better response to ...formed and should not influence the ... Voir le document complet

... metastatic and recurrent disease Outside specific clinical trials, patients with metastatic disease ought to receive therapy similar to that given for localized disease, with appropriate local ... Voir le document complet

... metastatic and recurrent disease Outside specific clinical trials, patients with metastatic disease ought to receive similar therapy to that given for localized disease, with appropriate local ... Voir le document complet

... Minimum Clinical Recommendations for diagnosis, treatment and follow-up of soft tissue sarcomas Incidence ...sarcoma in the European Union is ...frequent ... Voir le document complet

... of patients, overall survival outcomes from the sequential use of single cytotoxic drugs is equivalent to that of combination chemotherapy, with less associated toxicity and better quality of ...Therefore, ... Voir le document complet