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[PDF] Top 20 PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity

Has 10000 "PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity" found on our website. Below are the top 20 most common "PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity".

PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity

PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity

... PI3Kg in obesity-driven inflammation and insulin resistance depends largely on its role on adiposity, which is mediated by PI3Kg activity in a cell type outside the ... Voir le document complet

10

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

... resistance and NAFLD [4–7,27,28]. Our data indicate that during obesity progression, Cnr2 expression undergoes a strong increase in adipose tissue parallel to the ... Voir le document complet

13

A decrease in brown adipose tissue activity is associated with weight gain during chemotherapy in early breast cancer patients

A decrease in brown adipose tissue activity is associated with weight gain during chemotherapy in early breast cancer patients

... mass in patients with and without 18 F-FDG uptake [ 38 ...BAT activity was associated with a low ratio of abdominal fat to total fat, and alongside less abdominal ...decrease in BAT ... Voir le document complet

8

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en fr Decoding the role of GPS2 in transcriptional control of inflammation of adipose tissue during obesity Décodage du role de GPS2 dans le controle transcriptionnel de l'inflammation du tissu adipeux dans l'obésité

... discovered in yeast for its capacity to inhibit lethal G protein subunit-activating mutations in the pheromone response ...experiments in yeast and mammalian cells were it was described to ... Voir le document complet

295

Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.

Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.

... Genetic and Pharmacological Inhibition of HSL Improves Insulin Tolerance and Glucose Metabolism As a negative association was observed in humans between WAT lipolysis and insulin ... Voir le document complet

20

Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents

Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents

... reported in our earlier human studies that IL- 1Ra serum levels are better correlated with insulin sensi- tivity than with BMI [ 11 ], we used rodent models of IL-1Ra deficiency and excess to examine ... Voir le document complet

7

Inhibition of p38mapk reduces adipose tissue inflammation in aging mediated by arginase-II

Inhibition of p38mapk reduces adipose tissue inflammation in aging mediated by arginase-II

... increase in Arg-I in the adipose tissue of Arg-II −/− mice, a similar finding reported in gastric tissues ...isoforms in adi- pose tissues in obesity and ... Voir le document complet

14

Relationships between glycaemic abnormalities, obesity and insulin resistance in nondiabetic Polynesians of New Caledonia.

Relationships between glycaemic abnormalities, obesity and insulin resistance in nondiabetic Polynesians of New Caledonia.

... design and/or 10 conduction of the CALDIA Study. Coordination, INSERM - in France: L Papoz (principal coordinator), D Simon, J Cubeau, A Lacroux, A Forhan and A Ponton; in New Caledonia: S ... Voir le document complet

18

Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode

Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode

... deficiency in the brown ...Bscl2 in NTC or SKD brown ...(B) and microscopic (C) levels in control (NTC) and SKD ...(E) and Dio2 (F) in NTC and SKD brown adipocytes ... Voir le document complet

13

MR (Mineralocorticoid Receptor) Induces Adipose Tissue Senescence and Mitochondrial Dysfunction Leading to Vascular Dysfunction in Obesity

MR (Mineralocorticoid Receptor) Induces Adipose Tissue Senescence and Mitochondrial Dysfunction Leading to Vascular Dysfunction in Obesity

... Abstract Adipose tissue (AT) senescence and mitochondrial dysfunction are associated with ...Studies in obese patients and animals demonstrate that the mineralocorticoid receptor (MR) ... Voir le document complet

30

Adipose tissue fibrosis assessed by high resolution ex vivo MRI as a hallmark of tissue alteration in morbid obesity

Adipose tissue fibrosis assessed by high resolution ex vivo MRI as a hallmark of tissue alteration in morbid obesity

... Single-slice and total (over three contiguous slices) fibrosis fractions were measured from T1 maps computed from the RARE sequence using the k-means classification method ...fibrosis and fat. MRI ... Voir le document complet

8

Adaptive Expression of MicroRNA-125a in Adipose Tissue in Response to Obesity in Mice and Men

Adaptive Expression of MicroRNA-125a in Adipose Tissue in Response to Obesity in Mice and Men

... surgery and 7 non-obese subjects were included in a study protocol approved by the Ethics Committee of Hotel-Dieu Hospital, and signed informed written ...listed in Table 1. In the ... Voir le document complet

14

Quantitative CT imaging for adipose tissue analysis in mouse model of obesity

Quantitative CT imaging for adipose tissue analysis in mouse model of obesity

... ABSTRACT In obese humans CT imaging is a validated method for follow up studies of adipose tissue distribution and quantification of visceral and subcutaneous ...methods in ... Voir le document complet

9

New CT imaging method for adipose tissue analysis in mouse model of obesity

New CT imaging method for adipose tissue analysis in mouse model of obesity

... deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private research ... Voir le document complet

2

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

... Thus, in the absence of DCA-driven BAT thermo- genesis, Klb –/– mice become susceptible to hepatosteatosis and phenocopy Fgf21 –/– mice (27, ...observed in Klb –/– mice may result directly from the ... Voir le document complet

16

Vitamin D status is not related to insulin resistance in different phenotypes of moderate obesity

Vitamin D status is not related to insulin resistance in different phenotypes of moderate obesity

... Manal Al Masri, Ahmed Jérôme Romain, Catherine Boegner, Laurent Maïmoun, Denis Mariano-Goulart, Vincent Attalin, Elodie Leprieur, Marion. Picandet, Antoine Avignon, Ariane Sultan[r] ... Voir le document complet

6

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

... /h) during light and dark phases. G) Hepatic mRNA levels of ligand and receptors of the FGF signaling pathway ...-/- and N=11 WT male mice per ...Ucp1 in WT group; ... Voir le document complet

4

Lipophilic Micronutrients and Adipose Tissue Biology

Lipophilic Micronutrients and Adipose Tissue Biology

... 1. Adipose Tissue, an Endocrine Tissue Involved in Obesity and Associated Pathologies Adipose tissue is an organ actively involved in maintaining metabolic ... Voir le document complet

29

Osteoprotegerin in relation to insulin resistance and blood lipids in sub-Saharan African women with and without abdominal obesity

Osteoprotegerin in relation to insulin resistance and blood lipids in sub-Saharan African women with and without abdominal obesity

... obese and 16 non obese were re- cruited within the general population of Edéa, ...cm, and weight in light clothes to the nearest 0.1 kg, and we then calculated the body mass index (BMI) as ... Voir le document complet

5

Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue

Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue

... droplets in their cytoplasm (Fig. 4 C). In contrast, Egr1 deletion led to a robust differentiation of 78% of mutant mASC-Egr1 −/− cells into beige adipocytes ...differentiation in wild type mASC is a ... Voir le document complet

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