[PDF] Top 20 Activation-induced cell death in T lymphocytes from multiple sclerosis patients.
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Activation-induced cell death in T lymphocytes from multiple sclerosis patients.
... Introduction Multiple sclerosis (MS) is an autoimmune disease affecting the cen- tral nervous system and a leading cause of neurological disability in young ...results in demyelination and ... Voir le document complet
5
Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines
... astrocytes in this pathology. In MS, immune cells infiltrate the CNS pa- renchyma from the periphery, which leads to destruction of the myelin sheath and damages to ...mostly in mice (EAE ... Voir le document complet
13
Attempt to isolate infectious agent from bone-marrow of patients with multiple sclerosis
... mitogen-activated lymphocytes (C'). 0-2 ml samples from A were placed in triplicate in tube ...cells from groups B, C, and C'. The cell lines employed to rescue the agent ... Voir le document complet
2
IRX-2, a novel immunotherapeutic, protects human T cells from tumor-induced cell death.
... 20 in each group) with tacrolimus (n = 21) in de novo kidney allograft recipients ...[19]. Patients also received an IL-2 receptor antagonist, MMF and ...nephropathy in CP30 patients, ... Voir le document complet
6
Serum-Mediated Oxidative Stress from Systemic Sclerosis Patients Affects Mesenchymal Stem Cell Function
... obtained from SSc patients (SSc-MSCs) may present altered functions, use of allogeneic MSCs could be more appropriate in the clinics and has already shown some promising results ( 10 ...and ... Voir le document complet
12
CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion
... proteins in the central nervous system is unknown, as they lack any known motifs or functional ...involved in regulating the translational machinery at the synaptic terminal that is disrupted in ... Voir le document complet
12
Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study.
... response in patients with progressive MS are ...distinction in MS types appears to be reflected by the unsuccessful treatment of PPMS with powerful disease modifying ...drugs. In turn, this ... Voir le document complet
10
Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models
... cells, activation of naïve CD8 + T cells requires an efficient interaction with a professional APC ...located in different areas in and around the CNS may present CNS- derived antigens to CD8 + T ... Voir le document complet
42
CD4CD8aa Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease
... described in the blood of patients and healthy donors among which CD4CD8ab lymphocytes expressing high levels of CD4, CD8a and CD8b, and CD4CD8aa lymphocytes that expressed low levels of CD8a ... Voir le document complet
17
Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis
... B Cell Transmigration Assay through Endothelial Cell ...endothelial cell line HCMEC/D3 is an immortalized endothelial cell line derived from a primary cell culture coexpressing ... Voir le document complet
13
The IL‐27/IL‐27R axis is altered in CD4 + and CD8 + T lymphocytes from multiple sclerosis patients
... response in CD4 + and CD8 + T-cell subsets from MS patients We and others have previously shown that T lymphocytes from MS patients exhibit enhanced response to ...T ... Voir le document complet
19
Macrophage alternative activation confers protection against lipotoxicity-induced cell death
... to cell death by fasting-induced ...FA-induced cell death and in flammation is intimately linked. In the microenvironment of adipose tissues where local free FA ... Voir le document complet
13
Dual role of CD38 in microglial activation and activation-induced cell death.
... HAL Id: inserm-00375651 https://www.hal.inserm.fr/inserm-00375651 Submitted on 5 May 2009 HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether ... Voir le document complet
10
Loss of IL-10 secretion by regulatory B lymphocytes in multiple sclerosis patients
... All patients suffered from MS and had not received immune drugs since at least 6 ...B cell subsets have been analysed using different specific markers: CD19 + CD27 + memory B cells, CD19 + CD38 dim ... Voir le document complet
2
A Belgian consensus protocol for autologous hematopoietic stem cell transplantation in multiple sclerosis.
... Background Multiple sclerosis (MS) is an immune mediated inflamma- tory disorder of the central nervous system, with a preva- lence of 83 per 100,000 in Europe [ 1 ] corresponding with an estimated ... Voir le document complet
8
A Belgian consensus protocol for autologous haematopoietic stem cell transplantation in multiple sclerosis
... Multidisciplinary evaluation by the neurologist and hae- matologist should take place at initial evaluation, day 100 after transplant and yearly thereafter. All the participating members agreed upon this. Time points of ... Voir le document complet
8
Imaging biomarkers in Multiple Sclerosis: from image analysis to population imaging
... Biomarkers in Multiple Sclerosis MS is a chronic autoimmune demyelinating disorder of the ...point in an individual’s personal, family, professional and social ...accumulation in MS is ... Voir le document complet
14
Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae
... myelin in the ...antibodies from MS patient sera to hyperglucosylated antigen I(Glc), immunohistochemistry experi- ments on normal and experimental autoimmune encephalomyelitis (EAE) mouse spinal cords were ... Voir le document complet
14
Using GAit Measuring System (GAIMS) to discriminate patients with multiple sclerosis from healthy person
... distances in 274 directions spanning an angle of 96° at 15 ...result in a point cloud varying according to the position, the orientation, and the pose of the ...person. From this point cloud, the ... Voir le document complet
1
Deciphering Distance-Induced Deceleration of Gait and Ataxia in People with Multiple Sclerosis
... decrease in WS and other efficiency of gait descriptors was observed in each group when comparing their value over the first and the last 100m of the T500MW (paired compairon yielding a p-‐value < ... Voir le document complet
1
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