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[PDF] Top 20 Acetate metabolism in cancer cells

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Acetate metabolism in cancer cells

Acetate metabolism in cancer cells

... Access Acetate metabolism in cancer cells Aaron M Hosios 1 and Matthew G Vander Heiden 1,2* Macromolecule biosynthesis is required to duplicate cell components and support ...by ... Voir le document complet

3

Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy

Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy

... OXPHOS in tumors treated with anti-angiogenic drugs [ 7 , 10 – 12 ], much less is known with regard to perturbations of other metabolic ...Alterations in lipid metabolism have been reported by many ... Voir le document complet

19

Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells

Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells

... by cancer cells to provide macromolecules is glutaminolysis, which generates reductive equivalents such as NADPH by replenishing the TCA cycle [ 4 ...acid in the sense that, under normal conditions, ... Voir le document complet

14

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

... Comprehensive Cancer Center and ERTICA EA4677 Research Team, University of Auvergne, Clermont-Ferrand, France, 2 INRA, UMR 1019, UNH, Clermont- Ferrand, France, 3 Laboratoire de biochimie me´dicale, Centre de ... Voir le document complet

13

β-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells

β-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells

... hub in several cellular processes including cell adhesion, metabolism, and epithelial mesenchymal ...knockdown in the breast cancer cell line ...processes. In detail, proteins involved ... Voir le document complet

18

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

... Comprehensive Cancer Center and ERTICA EA4677 Research Team, University of Auvergne, Clermont-Ferrand, France, 2 INRA, UMR 1019, UNH, Clermont- Ferrand, France, 3 Laboratoire de biochimie me´dicale, Centre de ... Voir le document complet

13

Metabolism and proliferation share common regulatory pathways in cancer cells.: metabolism, proliferation, and cancer

Metabolism and proliferation share common regulatory pathways in cancer cells.: metabolism, proliferation, and cancer

... of cancer cells were changes in metabolism. Early in the last century, Otto Warburg (1930) observed that tumor cells have a higher rate of glucose metabolism than their ... Voir le document complet

25

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

... Slc7a11 in KP SAM CRISPRa cell lines with sgRNAs targeting each gene of interest (n = 3, technical ...gene in sgCtrl cells. (d) Proliferation of KP SAM CRISPRa cells expressing sgRNAs against ... Voir le document complet

24

Cancer Cell Metabolism: One Hallmark, Many Faces

Cancer Cell Metabolism: One Hallmark, Many Faces

... determinants in the regulation of tumor cell metabolism appears to be complex and not simply one of cause and ...or in response to hypoxic stress, one of its downstream consequences remains the ... Voir le document complet

37

Heterogeneity in Cancer Metabolism: New Concepts in an Old Field

Heterogeneity in Cancer Metabolism: New Concepts in an Old Field

... shown in gli- omas and leukemia (39, 158, 230), but associated with MYC pathway activation and glutaminase overexpression (209), thereby corroborating previous data on glutamine addiction in triple-negative ... Voir le document complet

25

Intracellular galectins in cancer cells: Potential new targets for therapy (Review)

Intracellular galectins in cancer cells: Potential new targets for therapy (Review)

... although cells often express more than one intracel- lular ...breast cancer cells express galectin-3, -8 and -9 ...case in point is the mitochondria, where both galectin-3 and -7 are ... Voir le document complet

14

Characterizing the Expression of Cytochrome P450s in Breast Cancer Cells

Characterizing the Expression of Cytochrome P450s in Breast Cancer Cells

... CYP450s in breast cancer cell ...evaluated in seven breast cancer, and one benign breast cell ...visualized in Figure 1, 2 and ...mainly in one cell line, while others are more ... Voir le document complet

139

ATP Consumption Promotes Cancer Metabolism

ATP Consumption Promotes Cancer Metabolism

... and in- creased glycolytic flux. In a series of experiments to determine how ENTPD5 increases glucose entry into glycolysis, Fang et ...increases in cells following ENTPD5 knockdown, ... Voir le document complet

4

Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression.

Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression.

... MDAMB231 cells (Supplementary ...PC3 cells exposed to the combined treatment are characterized by a denser ER lumen (see arrows ...S4). In order to inves- tigate the ER stress response, we measured ... Voir le document complet

14

C and 15 N natural isotope abundance reflects breast cancer cell metabolism OPEN

C and 15 N natural isotope abundance reflects breast cancer cell metabolism OPEN

... perturbations in arginine metabolism (urea cycle), thereby causing changes in N excretion and thus, by mass balance, in 15 N-abundance and N elemental ...signature in biopsies may have ... Voir le document complet

10

Gene co-expression analysis unravels a link between C9orf72 and RNA metabolism in myeloid cells

Gene co-expression analysis unravels a link between C9orf72 and RNA metabolism in myeloid cells

... myeloid cells, in particular acute myeloid leukemia cells, were by far the most inform- ative ...correlations. In addition, it is worth noting that in the BioGPS Affymetrix expression ... Voir le document complet

3

On the epigenetic origin of cancer stem cells

On the epigenetic origin of cancer stem cells

... 452 [37] Y.P. Choi, H.S. Shim, M.Q. Gao, S. Kang, N.H. Cho, Cancer Lett. 307 (2011) 62–71. 453 [38] C.L. Chaffer, I. Brueckmann, C. Scheel, A.J. Kaestli, P.A. Wiggins, L.O. Rodrigues, M. 454 Brooks, F. Reinhardt, ... Voir le document complet

8

Targeting Cancer Stem Cells to Overcome Chemoresistance

Targeting Cancer Stem Cells to Overcome Chemoresistance

... pumps in cancer cells [ 24 , 25 ] and also in cancer stem cells leading to chemoresistance [ 26 – 28 ...transporters in cancer stem cells, especially ABCG2 ... Voir le document complet

25

Fatty acid metabolism and modulation of human breast cancer cell survival

Fatty acid metabolism and modulation of human breast cancer cell survival

... We focused specifically on the role of TG accumulation induced by treatment with oleate in the protection from apoptosis induced by serum and growth factor (GF) withdrawal in two ceil un[r] ... Voir le document complet

169

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells

... destabilization in response to extracellular cues establishes the first example of miRNAs regulating their own sponges as a part of a reg- ulatory feedback ...mechanism in non-diabetic individuals. Results ... Voir le document complet

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