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Willebrand factor

Clearance of von Willebrand factor.: Clearance of von Willebrand factor

Clearance of von Willebrand factor.: Clearance of von Willebrand factor

... One important player of the haemostatic system is von Willebrand factor (VWF). VWF is a multimeric protein which contributes to the initial recruitment of platelets to injured vessel by acting as a ...

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ADAMTS13 and von Willebrand factor assessment in steady state and acute vaso‐occlusive crisis of sickle cell disease

ADAMTS13 and von Willebrand factor assessment in steady state and acute vaso‐occlusive crisis of sickle cell disease

... • VWF and ADAMTS13 IgG are increased in VOC-complicated SCD. 1 | INTRODUCTION Sickle cell disease (SCD) is the most frequent monogenic disease worldwide and results from a single amino-acid mutation of the beta-globin ...

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Differential expression of CD31 and von Willebrand factor on endothelial cells in different regions of the human brain: potential implications for cerebral malaria pathogenesis

Differential expression of CD31 and von Willebrand factor on endothelial cells in different regions of the human brain: potential implications for cerebral malaria pathogenesis

... The distribution of endothelial cells in different human tissues such as the lungs, skin, bone marrow, lymph nodes, the heart, and the liver have been reported [ 15 ]. This study showed dynamic variations in the ...

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Factor VIII-von Willebrand factor complex inhibits osteoclastogenesis and controls cell survival.

Factor VIII-von Willebrand factor complex inhibits osteoclastogenesis and controls cell survival.

... Von Willebrand factor is a multimeric protein containing many binding domains for various proteins such as the D’-D3 domain which binds FVIII (19) and the A1 domain which can bind different proteins such as ...

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ATP Augments von Willebrand Factor-dependent Shear-induced Platelet Aggregation through Ca2+-Calmodulin and Myosin Light Chain Kinase Activation

ATP Augments von Willebrand Factor-dependent Shear-induced Platelet Aggregation through Ca2+-Calmodulin and Myosin Light Chain Kinase Activation

... of vascular diseases. In addition, platelets from patients with acute myocardial infarction (4) or cerebral ischemia (5) display enhanced SIPA in vitro. High shear stress is required for the interaction between von ...

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von Willebrand factor: at the crossroads of bleeding and thrombosis.

von Willebrand factor: at the crossroads of bleeding and thrombosis.

... As mentioned above, both proteolytic activity and thiol reductase activity of ADAMTS13 towards VWF are only functional when VWF is in its elongated form due to hydrodynamic forces. Interestingly, when elongated, VWF has ...

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In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A

In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A

... von Willebrand disease (VWD) are limited. Willebrand factor (VWF) is a polymeric protein that undergoes regulated dimerization and subsequent multimerization during its ...von Willebrand ...

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Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

... von Willebrand disease (VWD) is characterized by gain-of-function mutations in the gene coding for von Willebrand factor (VWF), which enhance the factor’s ability to bind platelet glycoprotein Ib α ...

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Facteur Willebrand et modifications hémodynamiques associées à l’utilisation de dispositifs cardiovasculaires : mécanisme et applications cliniques

Facteur Willebrand et modifications hémodynamiques associées à l’utilisation de dispositifs cardiovasculaires : mécanisme et applications cliniques

... von Willebrand Factor as Biomarkers of Aortic Stenosis Severity (from the Biomarkers of Aortic Stenosis Severity [BASS] ...von Willebrand disease: A synopsis of the 2008 NHLBI/NIH ...

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Thrombopénie néonatale révélant une maladie de Willebrand de type 2B : une cohorte nationale de 52 patients

Thrombopénie néonatale révélant une maladie de Willebrand de type 2B : une cohorte nationale de 52 patients

... von Willebrand disease and managed in a center for bleeding disorders of the French network, to focus on neonatal ...von Willebrand disease and 9 were symptomatic with mucosal or cutaneous ...von ...

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Factor Shares in the long run

Factor Shares in the long run

... The purpose of this study is to construct and then analyze a new dataset that systematically documents the labor share of national income for more than 200 countries over the past 70 years. Using new archival data on ...

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Zooming In on Equity Factor Crowding

Zooming In on Equity Factor Crowding

... Equity Factor strategies by mea- suring the correlation of market order flow with the strength of the trading signal that factor investors hy- pothetically ...Fama-French factor investing is close to ...

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Another look into the factor model black box: factor interpretation and structural (in)stability

Another look into the factor model black box: factor interpretation and structural (in)stability

... over factor rotations: it yields exact zero loadings (instead of very small loadings in absolute value), 11 and the output can here be governed by one or several hyperparam- eters, allowing for more flexibility ...

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Noise factor of MZPI radar

Noise factor of MZPI radar

... L’accès à ce site Web et l’utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D’UTILISER CE SITE WEB. NRC Publicat[r] ...

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CFD based form factor determination method

CFD based form factor determination method

... form factor with Prohaska method on KVLCC2 in ballast condition can be considered merely as a best case ...form factor predictions with the ITTC-57 line from the computations with recommended or standard ...

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Mean Configuration Factor: Infinite Strips

Mean Configuration Factor: Infinite Strips

... In this note, the mean configuration factor over an infinite strip receiver is evaluated,' the radiator being a second infinite strip and the axes of the two strips being parallel. In Fi[r] ...

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La cuestión institucional como factor de cambio

La cuestión institucional como factor de cambio

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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Statistical Properties of Factor Oracles

Statistical Properties of Factor Oracles

... the factor/suffix oracle with other indexing structures such as suffix trees, whose space occupancy closely depends on the number of its internal edges, that is known to be of order n/ log 2 (see ...

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The ice factor in frozen ground

The ice factor in frozen ground

... If the film is connected to adjacent films that have suffered no change, there will exist a difference in chemical potential and spreading pressures causing water to flow to the film [r] ...

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Tumor necrosis factor is a survival and proliferation factor for human myeloma cells.

Tumor necrosis factor is a survival and proliferation factor for human myeloma cells.

... survival factor for malignant plasma ...necrosis factor α (TNF-α) is also a survival factor for myeloma cell lines, although less potent than ...

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