Voltage-gated potassium channel
Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel
... affect channel activity ...the channel (25), and movements of the Cap domain might affect the conformations of the nearby cyclic nucleotide-binding homology domain, C-linker, voltage sensing domain, ...
17
Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit
... ion channel and they lack endogenous Kvb1 expression ( ...the voltage-gated potassium channel, regulates the rapid inactivation of Kv1 fam- ily channels ( 18 ...the ...
13
APETx4, a novel sea anemone toxin and a modulator of the cancer-relevant potassium channel KV10.1
... ether-à-go-go channel (hEag1 or K V 10.1) is a cancer-relevant voltage-gated potassium channel that is overexpressed in a majority of human ...this channel can be lead compounds ...
17
Two conserved arginine residues from the SK3 potassium channel outer vestibule control selectivity of recognition by scorpion toxins.: Key Residues of SK3 Channel for Selective Toxin Recognition
... ABSTRACT Potassium channel functions are often deciphered by the use of selective and potent scorpion ...SK channel recognition still remain ...SK3 channel outer vestibule in the selective ...
29
Voltage-gated ion channels and gating modifier toxins.
... for voltage-sensor trapping In order to gain insight into the three-dimensional structure of the -scorpion toxin/sodium channel complex, we modeled the β three-dimensional structure of the toxin-receptor ...
17
Voltage-gated sodium channels assemble and gate as dimers
... sodium channel α-subunit, Na v ...other voltage- gated sodium channel genes have also been linked to channelo- pathies such as epilepsy, myotonia, erythromelalgia, and ataxia 2 .... ...
15
Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
... the channel 1–3 . Members of this family include the cyclic nucleotide-gated channels (CNG), which are transducers in the olfactory and visual sensory system 2,4 , and the hyperpolarization-activated and ...
11
The Caenorhabditis elegans Iodotyrosine Deiodinase Ortholog SUP-18 Functions through a Conserved Channel SC-Box to Regulate the Muscle Two-Pore Domain Potassium Channel SUP-9
... To further understand how its C-terminal domain affects SUP-9 activity, we deleted in the sup-9 cDNA the region encoding the SUP-9 C-terminal cytoplasmic domain. We also replaced this region with the corresponding region ...
17
Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism
... from the American Type Culture Collection (CRL-1651) and cultured in Dulbecco’s modified Eagle’s medium (GIBCO) supplemented with 10% fetal calf serum and antibiotics (100 IU/ml penicillin and 100 µg/ml streptomy- cin) ...
19
Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas
... In the softshell clam, Mya arenaria, on the eastern coast of North America, two populations were studied by Bricelj et al. [ 18 ]: one of them, regularly exposed to bloom of Alexandrium spp., was proved to be resistant ...
24
On The Pixel Level Estimation of Pinning Voltage, Pinned Photodiode Capacitance and Transfer Gate Channel Potential
... pinning voltage is different or not based on the “knee voltage criterion” used in ...injection voltage (as expected for a PN junction) and the ...
5
Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin
... email :jerome.busserolles@uca.fr ; tel 33(0) 4 73 17 82 35 fax 33(0) 4 73 27 71 62 The authors have declared that no conflict of interest exists. Abstract: Neurotoxicity remains the most common adverse effect of ...
44
Gated networks: an inventory
... 2.3 V ARIATIONS ON THE CENTRAL TENSOR The architecture outlined in Section 2.2.2 can be seen either as a particular way to parametrize the global 3-way tensor, introducing features into its internal structure, or as a ...
18
Dual regulation of the native ClC-K2 chloride channel in the distal nephron by voltage and pH
... that voltage dependence, a general property of ClC Cl − channels (Uchida and Sasaki, 2005; Jentsch, 2008; Stölting et ...ClC-K2 channel. Previous studies on the regulation by membrane voltage of ...
19
Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels.
... One key feature of G protein modulation of Ca V channels is its transient relief by a strong depolarizing prepulse. This phenomenon called facilitation is attributed to the dissociation of Gβγ dimers as channels undergo ...
39
Potassium Use Efficiency of Plants
... Potassium Use Ef ficiency of Plants Philip J. White, Michael J. Bell, Ivica Djalovic, Philippe Hinsinger, and Zed Rengel Abstract There are many terms used to de fine aspects of potassium (K) use effi- ciency ...
28
The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1.
... where Q max is the maximum charge, V is the membrane potential, V m Q1/2 is the charge movement half activation potential, and is – K the steepness of the curve. When cells were pooled for the analysis, Q max was ...
18
A simple modification of dialysate potassium: its impact on plasma potassium concentrations and the electrocardiogram
... studied 12 patients considered at high risk of arrhythmia and compared 3 weeks of dialysis with a constant K concentration in the dialysate with 3 weeks of dialysis with K dialysate con-[r] ...
8
Glycogen synthase kinase 3-mediated voltage-dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation.
... Cecile Martel, Maya Allouche, Davide Degli Esposti, Elena Fanelli, Céline Boursier, Céline Henry, Joel Chopineau, Giuseppe Calamita, Guido Kroemer,. Antoinette Lemoine, et al[r] ...
48
Gaz quantiques de potassium 39 à interactions contrôlables
... Afin d’atteindre la condensation tout optique du 39 K, il est en premier lieu néces- saire de mettre en place un refroidissement dissipatif efficace, permettant de produire des nuages denses et froids afin de charger ...
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