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virus-like particles

Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles

Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles

... Eidgenössische Technische Hochschule, Zürich, Switzerland ; INRS-Institut Armand-Frappier, Université du Québec, Québec, Canada ; Facultad de Ciencias Biológicas, Universidad Andrés Bello, Santiago, Chile f How ...

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Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF

Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF

... influenza virus-like particles (VLPs) as vaccine candidate or delivery system is their heterogeneous ...these particles and identify proteins that are unique to each population, comparative ...

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Foot-and-mouth disease: optimization, reproducibility, and scalability of high-yield production of virus-like particles for a next-generation vaccine

Foot-and-mouth disease: optimization, reproducibility, and scalability of high-yield production of virus-like particles for a next-generation vaccine

... live virus, the need of an exhaustive purification process to eliminate non-structural proteins of the virus in the final formulations in order to differentiate infected from vaccinated animals and variable ...

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Bovine dendritic cell activation, T cell proliferation and antibody responses to foot-and-mouth disease, is similar with inactivated virus and virus like particles

Bovine dendritic cell activation, T cell proliferation and antibody responses to foot-and-mouth disease, is similar with inactivated virus and virus like particles

... Edited by: Cyril Gerard Gay, United States Department of Agriculture (USDA), United States Reviewed by: Venkatramana D. Krishna, University of Minnesota Twin Cities, United States Nicolas Bertho, INRA Biologie, ...

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High-Yield Production Process of Influenza Virus-Like Particles in Human Cells Toward Large-Scale Vaccine Manufacturing

High-Yield Production Process of Influenza Virus-Like Particles in Human Cells Toward Large-Scale Vaccine Manufacturing

... Le virus influenza a été la cause d’épidémies et de pandémies parmi les plus anciennes et meurtrières rapportées dans l’histoire de ...du virus, causant un manque de protection croisée contre certaines des ...

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Capture and purification of Human Immunodeficiency Virus-1 virus-like particles: Convective media vs porous beads

Capture and purification of Human Immunodeficiency Virus-1 virus-like particles: Convective media vs porous beads

... Fig. 3. SDS-PAGE (a), HIV-1 p24 (b) and H3-histone (c) Western blots and cryo-TEM micrographs (d) of relevant fractions from the capture and purification experiments using NatriFlo® HD-Q Recon membrane adsorber. M: ...

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Induction of neutralising antibodies by virus-like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses.

Induction of neutralising antibodies by virus-like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses.

... facilitates virus access to target cells at the early stages of infection and promotes egress of progeny viral particles from infected cells late in infection ...H7N1 virus has been described ...

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The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain

The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain

... Introduction The 3-O-(3',3'-dimethylsuccinyl)-betulinic acid (or YK- FH312 [1], or PA-457 [2], or Bevirimat™ [3,4]), has been used as an antiviral which blocks HIV-1 replication via its inhibitory activity on Gag ...

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Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein.

Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein.

... GFLV particles to expose HPV L2 epitope on its surface without interfering in VLP ...systems like CCMV and Faba bean necrotic yellows virus [ 26 , 44 ...GFLV particles indicating that the ...

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In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles.

In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles.

... Among methods for gene transfer into cells, viral gene- delivery system is a most effective method. In previous studies, we demonstrated that the recombinant JC virus major capsid protein, VP1, is able to ...

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Individual rotavirus-like particles containing 120 molecules of fluorescent protein are visible in living cells

Individual rotavirus-like particles containing 120 molecules of fluorescent protein are visible in living cells

... Rotaviruses are large, complex icosahedral particles consisting of three concentric capsid layers. When the innermost capsid protein VP2 is expressed in the bacu- lovirus-insect cell system it assembles as ...

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Development of a Production Process for a Virus Like Particle Based Vaccine in Cell Culture

Development of a Production Process for a Virus Like Particle Based Vaccine in Cell Culture

... total particles produced according to NSEM analysis. Considering the particles present in the NSEM influenza image that could be labeled as VLPs (Figure ...these particles are vesicles that have ...

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Ultrastructural characterization of Turnip mosaic virus induced cellular rearrangements reveal membrane-bound viral particles accumulating in vacuoles

Ultrastructural characterization of Turnip mosaic virus induced cellular rearrangements reveal membrane-bound viral particles accumulating in vacuoles

... gold particles per square micrometer and the rela- tive labeling distribution over mock-infected and TuMV-infected sec- tions were determined as described previously ( 30 ...

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Selective autophagy limits cauliflower mosaic virus infection by NBR1-mediated targeting of viral capsid protein and particles

Selective autophagy limits cauliflower mosaic virus infection by NBR1-mediated targeting of viral capsid protein and particles

... viral particles in infected plant tissue, we carried out immune pulldown experiments and found that both P4 and viral DNA coimmunoprecipitated with NBR1-GFP in stably transformed transgenic plants ...CaMV ...

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Discontinuous shear thickening in concentrated mixtures of isotropic-shaped and rod-like particles tested through mixer type rheometry

Discontinuous shear thickening in concentrated mixtures of isotropic-shaped and rod-like particles tested through mixer type rheometry

... of particles, as long as the coaxial plug can rotate as a solid body together with the double helix being subjected to lower stress levels than those expected in the gap between double helix and external ...

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A new bunya-like virus associated with mass mortality of white-clawed crayfish in the wild

A new bunya-like virus associated with mass mortality of white-clawed crayfish in the wild

... a virus detected as part of a metagenomics study of otter feces (Bodewes et ...crustacean virus 7 was not sequenced by Shi et ...the virus only in the two individuals sampled on the mortality front ...

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Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

... P 304–507 ) unambiguously shows that nucleocapsid formation is ac- celerated in droplets at the same global concentration of N 1–525 . DISCUSSION Nonsegmented negative-sense RNA viruses are known to form inclusion bodies ...

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Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection.

Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection.

... Infection by vDN1L induced an increased NK activity at early time points (day 4 p.i.) and therefore we measured if this affected the virus titres in the lungs at different times p.i. By 3 days p.i., the titres of ...

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Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness

Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness

... Few studies have prospectively assessed etiologies of acute re- spiratory infections in community-based elderly individuals [ 8 , 10 ]. Much of the available data describing RSV and other viral infections in the elderly ...

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Le virus de l’hépatite E - Un virus méconnu qui se dévoile

Le virus de l’hépatite E - Un virus méconnu qui se dévoile

... laurence.cocquerel@ibl.cnrs.fr Alors que les hépatites virales A, B et C sont connues du grand public, l’hépatite E est généralement méconnue. Cette infection, dont l’agent responsable est le virus de l’hépatite E ...

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