viral DNA
Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import
... detect viral DNA integra- tion in each C-terminal mutant infection ...ciated viral DNA ...affect viral integration during their ...for viral DNA integration, as suggested ...
15
Viral DNA in horses infected with equine infectious anemia virus.
... The amount and distribution of viral DNA were established in a horse acutely infected with the Wyoming strain of equine infectious anemia virus (EIAV).. The highest concentrations of vir[r] ...
7
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
... episomal DNA, which resulted in a lack of activity for Cas9/sg21 in de novo infection experiments (data not ...anti- viral effects (Fig S2), suggesting that this strategy may further maximize ...
10
Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities
... of viral DNA by these three ...retroviral DNA, and that such a ranking is only governed by the binding enthalpies, ΔH, the entropy undergoing marginal ...with DNA could be necessary to further ...
22
Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects
... cular DNA ( Beauregard et ...total DNA was extracted and treated with DNase Plasmid-Safe, an ATP-dependent DNase that re- moves linear ...treatment, DNA was analyzed by PCR using primers for viruses, ...
22
Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating
... Engineering of Disulfide Intersubunit Bridges Between Stopper Par- allel -Strands and DNA Ejection Through the SPP1 Connector. Posi- tioning of the large loop 2⬘3 in the stopper region identified the gp16 ...
7
Human DNA decays faster with time than viral dsDNA: an analysis on HPV16 using pathology archive samples spanning 85 years
... that DNA integrity decreased in FFPE sam- ples stored with eight years of difference [ 1 ...human DNA quality, as estimated by qPCR in terms of amplifiable length, is lower and only a minority of the ...
9
Rôle de la structure du génome viral sur la réplication du virus de l’hépatite C
... Chez les Picornaviridae, le 3’UTR de l’ARN génomique nommé aussi oriR est une région hautement structurée. Pour le poliovirus cette région est formée de deux structures tige- boucles et d’une séquence poly-adénylée. Ces ...
319
Le « biofilm viral » : un nouveau mode de dissémination des virus ?
... biofilm viral, préformé à la surface des cellules infectées, est essentiel pour stocker le pathogène, en concentrer le pouvoir infectieux, et permettre sa dissémi- nation lors de contacts entre ...biofilm ...
3
Capsid catalysis : de novo enzymes on viral proteins
... While M13 clone DDAH successfully catalyzes copper oxidase activity, a higher throughput method of assaying potential biocatalytic clones could identify a phage with [r] ...
119
Competitive interference between influenza viral strains
... Competitive interference between influenza viral strains Moghadas, Seyed M.; Bowman, Christopher S.; Arino, Julien https://publications-cnrc.canada.ca/fra/droits L’accès à ce site Web et l’utilisation de son ...
9
Modelling the evolution of viral oncogenesis
... In our modelling approach, we have voluntarily restricted the range of scenarios to explore by as- suming that viruses from the three life cycles have the same parameter values. In spite of this con- straint, we find ...
14
Les exosomes - Des transporteurs d’ARN viral qui stimulent l’immunité innée
... médecine/sciences 2013 ; 29 : 104-6 Diversité des particules virales produites par les cellules infectées Les cellules infectées peuvent produire des particules virales qui, infectieuses ou non, revêtent différentes ...
3
Evolvability drives innovation in viral genomes
... in viral genomes are driven by rare events that move the virus to a new position on the fitness landscape where the local curvature is steep enough as to trigger a cascade of favorable mutations ...
7
Viral Vectors for Plant Genome Engineering.
... for viral movement and contain genes encoding 134- and 194-kDa replicase proteins, a 29-kDa MP and a 16-kDa cysteine-rich protein whose function is not fully ...
6
Alvira : comparative genomics of viral strains
... of viral strains Francois Enault 1, * ,† , Romain Fremez 1 , Eric Baranowski 2 and Thomas Faraut 1 ¸ 1 Laboratoire de Genetique Cellulaire INRA UMR444, Chemin de Borde Rouge BP52627 31326 Castanet Tolosan ´´ Cedex ...
2
View of Viral and fungal infections
... L’objectif de cette étude était de décrire les tableaux cliniques des patients hospitalisés dans le seul service de réanimation d’un dépar- tement insulaire dans les suites d ’une infect[r] ...
4
Statistical mechanics of viral-immune co-evolution
... whereas influenza B split decades ago into independent lineages [ 175 ]. In Chapter 3 we studied numerically an agent-based model and we mapped quantitatively the emerging patterns onto the model parameters. This map ...
211
Fluorescence of DNA Duplexes: From Model Helices to Natural DNA
... motions of a given duplex will affect the relaxation of its excited states and, consequently, its fluorescence properties. The corollary is that any factor having an impact on the conformational motions of the duplex ...
18
RIG-I - Un commutateur moléculaire détecteur d’ARN viral
... Structure cristallographique de la forme autoréprimée de RIG-I. Les domaines CARD, liés à l’hélicase au niveau du sous-domaine Hel1, interagissent avec le sous-domaine Hel2i via des interactions CARD2-Hel2i. Le domaine « ...
3