varicella-zoster
Varicella-zoster virus induces apoptosis in cell culture
... by varicella-zoster virus (VZV), a human herpesvirus, is characterized by nuclear fragmentation of DNA into oligonucleosomal fragments and by chromatin ...
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Varicella-zoster virus IE63, a virion component expressed during latency and acute infection, elicits humoral and cellular immunity
... to varicella-zoster virus and its ...B. Varicella- relevance to vaccine ...75. zoster virus latency in the adult rat is a useful model for human latent ...of varicella-zoster ...
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Varicella-zoster virus gene 63 encodes an immediate-early protein that is abundantly expressed during latency
... Laboratory of Fundamental Virology,Institute of Pathology, University of Liège, B-4000 Liège, Belgium [2] Laboratory of Dermatopathology Institute of Pathology, University of Liège, B-4000 Liège, Belgium Abstract : ...
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Varicella-zoster virus IE63 protein represses the basal transcription machinery by disorganizing the pre-initiation complex
... Abstract Using transient transfection assays, regulation properties of Varicella-Zoster Virus (VZV)-encoded IE63 protein were analyzed on several VZV immediate early (ORF4), early (ORF28) and late (ORF67) ...
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Varicella-zoster virus open reading frame 4 encodes an immediate-early protein with posttranscriptional regulatory properties
... Belgium Varicella-zoster virus (VZV) encodes four putative immediate-early proteins based on sequence homology with herpes simplex virus type 1: the products of ORF4, -61, -62, and ...
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Varicella-Zoster Virus IE4 Protein Interacts with SR Proteins and Exports mRNAs through the TAP/NXF1 Pathway.
... the Varicella-Zoster virus (VZV) IE4 protein acts as an important regulator on VZV and cellular genes expression and could exert its functions at post-transcriptional ...
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Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.
... of Varicella-Zoster virus (VZV) infection, IE63 (immediate early 63 protein) is mostly expressed in the nucleus and also slightly in the cyto- plasm, and during latency, IE63 localizes in the cyto- plasm ...
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Characterization of the regulatory functions of varicella-zoster virus open reading frame-4 gene-product
... Belgium Varicella-zoster virus (VZV) open reading frame 4 (ORF4) encodes a protein with a predicted molecular weight of 51,540 presenting amino acid sequence homology with the immediate-early regulatory ...
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The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3.
... 1 GIGA-Research, Laboratory of Virology and Immunology, University of Liege, Liege, Belgium, 2 Laboratory of Molecular Oncology (LOM), Institut d’Investigacio´ Biome`dica de Bellvitge (IDIBELL), Barcelona, Spain, 3 ...
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Activation of the human immunodeficiency virus long terminal repeat by varicella-zoster virus IE4 protein requires nuclear factor-kB and involves both the amino-terminal and the carboxyl-terminal cysteine-rich region
... Varicella-zoster virus (VZV) 1 is an α -herpesvirus, which causes two distinct diseases in man: chicken pox and shingles. Shortly after entry into the infected cells, VZV genes are expressed in a temporal ...
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The role of varicella zoster virus immediate-early proteins in latency and their potential use as components of vaccines
... by varicella-zoster virus open reading frames (ORFs) 4 and 63, but not ORF 61, are associated with purified virus ...The varicella-zoster virus immediate-early protein IE62 is a major ...
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The Varicella-Zoster virus IE4 protein: a conserved member of the herpesviral mRNA export factors family and a potential alternative target in antiherpetic therapies
... A B S T R A C T During a viral infection, in addition to cellular mRNAs, amounts of viral mRNAs have to be efficiently transported to the cytoplasm for translation. It is now established that herpesviruses encode a ...
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Study of the role of the complex formed by the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress
... the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress Julien LAMBERT 1 , Marielle LEBRUN 1 , Laura RIVA 1 , Judit SÁNCHEZ GIL 1 , Graciela ANDREI 2 , Robert SNOECK 2 ...
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Deletion of the ORF9p acidic cluster impairs the nuclear egress of Varicella-zoster virus capsids.
... The protein encoded by ORF9 is essential for varicella-zoster virus (VZV) replication. Previous studies documented its presence in the trans-Golgi network and its involvement in secondary envelopment. In ...
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Comment on “Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination”
... References: 1. Q. Qi, M. M. Cavanagh, S. Le Saux, H. NamKoong, C. Kim, E. Turgano, Y. Liu, C. Wang, S. Mackey, G. E. Swan, C. L. Dekker, R. A. Olshen, S. D. Boyd, C. M. Weyand, L. Tian, J. J. Goronzy, Diversification of ...
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Varicella-Zoster virus gene expression in latently infected rat dorsal root ganglia.
... Words: Varicella-Zoster Virus (VZV); latency; dorsal root ...INTRODUCTION Varicella-Zoster virus (VZV) is a human herpesvirus which causes varicella (chickenpox) as a primary infec- ...
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Varicella Zoster Virus ORF9p: hijacker of the autophagy pathway?
... Varicella Zoster Virus ORF9p: hijacker of the autophagy pathway? Lambert, J. 1 , Thiry, M. 2 , Sadzot-Delvaux, C. & Lebrun, M. 1 1 Laboratory of Virology and Immunology, GIGA-I³, University of Liège, ...
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Varicella-zoster virus modulates NF-kappaB recruitment on selected cellular promoters.
... causes varicella (chicken pox), establishes latency in sensory ganglia, and may reactivate to cause herpes zoster (shingles) in the host ...acute varicella infection produce larger amounts of IFN-$, ...
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Chronic verrucous varicella zoster virus skin lesions: clinical, histological, molecular and therapeutic aspects
... alternative therapeutic management using antiviral agents that target the viral DNA polymerase. Introduction The varicella-zoster virus (VZV) is the infectious agent responsible for chickenpox and shingles. ...
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Distribution of varicella-zoster virus DNA and gene products in tissues of a first-trimester varicella-infected fetus.
... about varicella-zoster virus (VZV) infection in first-trimester fetuses remains ...After varicella infection was diagnosed in a woman, her 12-week-old fetus was aborted and was investigated, by ...
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