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urothelial carcinoma

The Immunoscore in Localized Urothelial Carcinoma Treated with Neoadjuvant Chemotherapy: Clinical Significance for Pathologic Responses and Overall Survival

The Immunoscore in Localized Urothelial Carcinoma Treated with Neoadjuvant Chemotherapy: Clinical Significance for Pathologic Responses and Overall Survival

... Clinical data were retrospectively collected and anonymized at each participating center prior to the central collection for analysis. Collected clinical data were related to the patients’ characteristics (sex, age at ...

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Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS)

Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS)

... Background: ATLAS evaluated the efficacy and safety of the PARP inhibitor rucaparib in patients with previously treated locally advanced/unresectable or metastatic urothelial carcinoma (UC). Methods: ...

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Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) Is Associated With Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract

Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) Is Associated With Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract

... Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) is Associated with Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract Jay D. Raman 1 , Joshua I. Warrick 1 , Carla ...

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Early objective response may not be a prognostic factor of survival for patients with metastatic urothelial carcinoma: from a retrospective analysis of a cohort of 113 patients

Early objective response may not be a prognostic factor of survival for patients with metastatic urothelial carcinoma: from a retrospective analysis of a cohort of 113 patients

... Methods This retrospective multicenter study involving seven French medical centers was approved by the French data protection authority (Commission Nationale Infor- matique et Liberté, CNIL) and was supported by the ...

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en fr Germline variation in inflammatory genes and CD8+ tumor microenvironment : prognostic value in urothelial carcinoma of the bladder Polymorphismes des gènes associés à l’inflammation et microenvironnement tumoral lymphocytaire CD8+ : valeur pronostique dans les carcinomes urothéliaux de la vessie.

... three studies showed statistically significant results in multivariate analysis, with strong infiltration by CD68 macrophages associated with adverse outcome [36,38,39] . Ayari et al. described that CD68 infiltration in ...

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Predictive factors of recurrence and survival of upper tract urothelial carcinomas.

Predictive factors of recurrence and survival of upper tract urothelial carcinomas.

... upper-tract urothelial carcinoma managed by radical nephroureterectomy? Urol ...L. Carcinoma of the upper urinary tract: predictors of survival and competing causes of ...

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Estimate of hepatocellular carcinoma incidence in patients with alcoholic cirrhosis

Estimate of hepatocellular carcinoma incidence in patients with alcoholic cirrhosis

... Primary liver cancer has a high incidence in Europe, especially in France, which has almost 9000 cases per year (1). In more than 90% of cases, hepatocellular carcinoma (HCC) occurs in patients with cirrhosis. ...

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Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

... We show the capture and analysis single cells, in particular human sinonasal squamous cell carcinomas (SCC), by the combination of di-electrophoresis (DEP) force and electrorotation, wi[r] ...

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The Role of Stroma in Breast Carcinoma Growth in Vivo

The Role of Stroma in Breast Carcinoma Growth in Vivo

... 16. K. Henning, H. Kosmehl, A. Berndt, P. Rousselle, and D. Gabier Katenkamp (1995). Differential expression of laminin chains is benign and malignant lesions of the breast. Pathol. Res. Pract. 191:175. 17. A. ...

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VEGF and VEGFR-1 are coexpressed by epithelial and stromal cells of renal cell carcinoma.: VEGF and its receptors in renal cell carcinoma

VEGF and VEGFR-1 are coexpressed by epithelial and stromal cells of renal cell carcinoma.: VEGF and its receptors in renal cell carcinoma

... PATIENTS AND METHODS Patients Between January 1998 and May 2001, 100 patients with untreated RCC were admitted to the department of urology of Hôpital Saint-Louis (Paris, France). RCC was histologically subclassified ...

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Snail and slug play distinct roles during breast carcinoma progression.

Snail and slug play distinct roles during breast carcinoma progression.

... apparently unrelated functions linked to cell survival (10, 11). In recent years, the roles of Snail and Slug in cancer progression have been postulated by several groups, based on distinct lines of evidence involving ...

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MITF: a genetic key to melanoma and renal cell carcinoma ?

MITF: a genetic key to melanoma and renal cell carcinoma ?

... Il est donc très intéressant de souli- gner que la mutation germinale p.E318K de MITF a également été détectée chez une série de patients ayant développé un carcinome à cellules réna[r] ...

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The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

... cell carcinoma: an inflammatory neoplasia A large amount of evidence indicates that RCC often displays prominent inflammatory features, characterized by the presence of almost all types of chemokines, cytokines ...

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Computational Modelling of Metastasis Development in Renal Cell Carcinoma

Computational Modelling of Metastasis Development in Renal Cell Carcinoma

... cell carcinoma, the initial model predicted a size distribution of metastatic foci that did not fit with observations obtained experimentally using magnetic resonance imaging (which provided size and number of ...

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Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

... hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort ...

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Compressive stress enhances coordinated migration of mammary carcinoma cells

Compressive stress enhances coordinated migration of mammary carcinoma cells

... mammary carcinoma cells in a coordinated sheet, initiated by “leader cells” – single cells at the leading edge of the sheet, extending long ...mammary carcinoma cells has significant implications for in ...

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Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

... Adrenocortical carcinoma is a rare neoplasm with a poor ...adrenocortical carcinoma pathogenesis but our understanding is still limited about the mechanisms that determine cancer spread and ...

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Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism.

Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism.

... colorectal carcinoma To determine whether CXCR3 is expressed in colon carcinoma (CRC), we analysed by quantitative RT – PCR (real-time quantita- tive reverse transcription polymerase chain reaction) the ...

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Analyzing GFP-tagged cytoskeletal protein colocalization in human carcinoma cells

Analyzing GFP-tagged cytoskeletal protein colocalization in human carcinoma cells

... Fluorescent dyes including Hoechst33342 staining the nucleus, 568 maleimide staining the whole cell, and AlexaFluor 647 phalloidin staining the actin, comprised three channels blu[r] ...

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Local Anesthetics Inhibit the Growth of Human Hepatocellular Carcinoma Cells

Local Anesthetics Inhibit the Growth of Human Hepatocellular Carcinoma Cells

... HuH7, HepaRG progenitors, and differentiated HepaRG cell lines were cultured in the presence of indicated concentrations of lidocaine (A) and ropivacaine (B) for 48 h and cell viabi[r] ...

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