type I regulatory T cells
IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production
... T cells with effector or regulatory functions. CD4 + regulatory T cell subsets include naturally occurring CD4 + CD25 + Treg cells (nTregs), which can be defined by their expression of the ...
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Type 1 regulatory T cells specific for collagen type II as an efficient cell-based therapy in arthritis
... Treg cells, there is no consensus to date about which Treg cell population is optimally suitable for clinical ...phase I clinical trials have tested the ability of ex vivo–expanded CD4 + CD25 + Treg ...
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Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells
... Narcolepsy type 1 (NT1) has been shown to result from a selective loss of hypothalamic hypocretin-secreting neurons with patients typically showing low CSF-hypocretin levels ( < 110 ...T cells (CD62L + ...
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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
... reg cells Data suggest that T reg cells present in the pancreas control the progression to destructive insulitis in prediabetic mice (Feuerer et ...reg cells may unleash T eff cell autoimmune attack ...
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Classical swine fever virus npro limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7
... 112 R) mutant fused to the GAL4 DNA-binding domain [GAL4-N pro and GAL4-N pro (C 112 R), respectively]. These constructs were transfected alone or in combina- tion with increasing amounts of 1 ng, 25 ng, 100 ng, 250 ng, ...
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Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
... liver cells, and while type 2 AIH autoantigens are specific to liver cells, type 1 AIH autoantigen are not [ 28 ...of type 2 AIH and have targeted either CYP2D6 or FTCD or ...express ...
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BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells
... resistant cells. a, DNA interactions gained in resistant cells based on SMC1A HiChIP ...loop type (structural (black), regulatory (blue)) are ...resistant cells at the three main anchor ...
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T follicular helper and T follicular regulatory cells have different TCR specificity
... T cells from TCR-transgenic mice, we demonstrate that recruitment of Tfh cells into GCs is predominantly controlled by specificity for the immunizing ...Tfr cells for the same GCs was not biased ...
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Regulatory role of natural killer T cells in diabetes
... t Type 1 and type 2 diabetes are growing public health ...(iNKT) cells are innate-like T cells that recognize glycolipids presented by ...These cells not only play a key role in the ...
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B cells with regulatory properties in transplantation tolerance
... the cells that express the most IL10 have the plasma cell marker CD138, suggesting that the most potent regulatory B cells are plasma cells [67] ...B cells enriched in the pool of IgM + ...
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Protozoan parasites and Type I IFNs
... NK cells and are involved in macrophage activation toward an M1 phenotype, which is required for the control of parasite multiplication during the acute phase of ...a type I and type II immune ...
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What is the Role for Regulatory T-Cells after Nonmyeloablative conditioning
... rospectively studied 162 patients who had been free from disease progression for more than 100 days after either unrelated BMT (n 5 75) or CBT (n 5 87) at Toranomon Hospital from January 2002 to December 2006. Median age ...
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Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells
... Tfr cells were similar after anti-PD-L1 treatment but that we observed a significant decrease in the frequency of Neuropilin-1 lo cells among these cells, suggesting that PD-L1 supports Tfr cell ...
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3D Chromosome Regulatory Landscape of Human Pluripotent Cells
... different cells and that transcriptional regulatory elements function within this context to produce cell-type specific gene expression ...human cells, and is evident even during stages of ...
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Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells
... the type I IFN response to IAV in these ...IFN regulatory elements (data not shown), suggesting that type I IFNs regulate the expression of this receptor, as reported for RIG-I ...
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Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses
... DNase I (Roche) in RPMI medium (Invitrogen) without ...Stromal cells were allowed to adhere to the collagen matrix and were washed after 24 h to remove non-adherent ...stromal cells lines were ...
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Regulatory T cells in solid organ transplantation
... in type 1 ...Treg cells at the 2 weeks and 6 months post-infusion renal ...Treg cells’ product was able to migrate into the ...Treg cells in the context of kidney ...
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Expansion of regulatory T cells in patients with Langerhans cell histiocytosis.
... LC-type cells in LCH granulomas have been found to be in an immature, or semimature, stage of differentiation in vivo and to only weakly stimulate allogeneic T cell proliferation ...T cells, ...
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ON STRONGLY ANISOTROPIC TYPE I BLOW UP
... 4. L ∞ bounds. The main difficulty of the analysis is to control the perturbation in L ∞ in order to deal with the nonlinear term. Here the computation of the free boundary and the construction of the reconnecting ...
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Regulatory myeloid cells: an underexplored continent in B-cell lymphomas
... arginase I and IDO activities were detected in plasma from DLBCLs, the suppressive activity of M-MDSC was not impaired in vitro in the presence of arginase- or IDO- ...arginase I and IDO ...
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