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Type 2 diabetes (T2D)

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

... Abstract Obesity is a chronic low-grade inflammatory disease (both at the systemic and adipose tissue level) that continues to rise worldwide. It is associated with an abundance of co- morbidities, including type ...

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An integrated approach for the identification of predictive markers of type 2 diabetes

An integrated approach for the identification of predictive markers of type 2 diabetes

... The trajectory and underlying mechanisms of health are determined by a complex interplay between intrinsic and extrinsic factors. There is a need for more accurate assessment of the inputs and their consequences to ...

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Canagliflozin: A Review in Type 2 Diabetes.

Canagliflozin: A Review in Type 2 Diabetes.

... Introduction Type 2 diabetes (T2D) is a chronic progressive metabolic disease characterized by hyperglycaemia, due to insulin resistance/insufficient insulin production [ 1 ...[ 2 ]. ...

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‘Treatment-resistant’ type 2 diabetes: Which definition for clinical practice?

‘Treatment-resistant’ type 2 diabetes: Which definition for clinical practice?

... ‘Treatment-resistant’ type 2 diabetes: Which definition for clinical practice? Despite being a common feature in clinical practice and a major challenge for healthcare providers involved in the ...

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Training-induced improvement in lipid oxidation in type 2 diabetes mellitus is related to alterations in muscle mitochondrial activity. Effect of endurance training in type 2 diabetes.

Training-induced improvement in lipid oxidation in type 2 diabetes mellitus is related to alterations in muscle mitochondrial activity. Effect of endurance training in type 2 diabetes.

... including type 2 diabetes mellitus [12] and obesity, where training induced an increase in size and content of mitochondria [9] and enhanced mitochondrial fatty acid oxidation ...

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Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes

Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes

... addition, plasma PCSK9 levels were assessed using a standardized protocol using the same assay throughout. Participants under statin therapy, an important confounding factor for PCSK9 levels, were also excluded [42]. ...

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Addition of incretin therapy to metformin in type 2 diabetes.

Addition of incretin therapy to metformin in type 2 diabetes.

... in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study ...

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DPP-4 inhibitors in the treatment of type 2 diabetes.

DPP-4 inhibitors in the treatment of type 2 diabetes.

... Linagliptin was also evaluated as monotherapy or add-on therapy and has shown clinically meaningful improvement of glycaemic control in type 2 diabetes. Linagliptin was given as monotherapy, 5mg once ...

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Bariatric surgery in patients with Type 2 diabetes: benefits, risks, indications and perspectives.

Bariatric surgery in patients with Type 2 diabetes: benefits, risks, indications and perspectives.

... of type 2 diabetes (T2DM), and weight loss is a major objective, although difficult to achieve with medical ...when diabetes is difficult to manage by medical means and other weight-related ...

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SGLT2 versus DPP4 inhibitors for type 2 diabetes.

SGLT2 versus DPP4 inhibitors for type 2 diabetes.

... With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized ...of diabetes in patients with chronic kidney ...

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Preventing, delaying, or masking type 2 diabetes with metformin in the diabetes prevention program?

Preventing, delaying, or masking type 2 diabetes with metformin in the diabetes prevention program?

... prevent diabetes or delay its onset cannot be determined completely by the existing ...of diabetes is clearly an important goal with major individual and public health ...as type 2 ...

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The endocannabinoid system: a promising target for the management of type 2 diabetes.

The endocannabinoid system: a promising target for the management of type 2 diabetes.

... shown to play a major role in EC degradation, the fatty acid amide hydroxylase (FAAH) and the monoacylglycerol lipase (MAGL) (figure 1) [42,45]. Mounting evidence suggests that the EC system is involved in the ...

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Treatment of type 2 diabetes.

Treatment of type 2 diabetes.

... of type 2 diabetes and the risk of severe side-effects of oral antidiabetic agents are markedly increased with aging, special focus should be put on the specific group of elderly diabetic patients ...

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Survival in people with type 2 diabetes as a function of HbA(1c).

Survival in people with type 2 diabetes as a function of HbA(1c).

... with type 2 diabetes (cohort 1 changed from monotherapy to combination oral therapy with metformin and a sulphonylurea; cohort 2 changed to insulin treatment) is that the 10% of patients with ...

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

... for type 2 diabetes mellitus, the mechanisms underlying the plasma glucose level‐lowering effects of metformin (1,1‐ dimethylbiguanide) still remain incompletely ...

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Oxidative Stress and Obesity- and Type 2 Diabetes-Induced Heart Failure

Oxidative Stress and Obesity- and Type 2 Diabetes-Induced Heart Failure

... 10. Steyn, M.; Zitouni, K.; Kelly, F.J.; Cook, P.; Earle, K.A. Sex Differences in Glutathione Peroxidase Activity and Central Obesity in Patients with Type 2 Diabetes at High Risk of Cardio-Renal ...

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Targeting the AMPK pathway for the treatment of Type 2 diabetes.

Targeting the AMPK pathway for the treatment of Type 2 diabetes.

... Benoît Viollet, Louise Lantier, Jocelyne Devin-Leclerc, Sophie Hébrard, Chloé Amouyal, et al... Tar- geting the AMPK pathway for the treatment of Type 2 diabetes...[r] ...

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Preventing and treating kidney disease in patients with type 2 diabetes

Preventing and treating kidney disease in patients with type 2 diabetes

... of diabetes mellitus, which may lead to end-stage renal disease (ESRD) [ 1 ...in type 2 diabetes (T2DM) than in type 1, especially because of the intervention of several other risk ...

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Hyperglycemia, type 2 diabetes, and depressive symptoms: the British Whitehall II study.

Hyperglycemia, type 2 diabetes, and depressive symptoms: the British Whitehall II study.

... between type 2 diabetes and depression, both major public health challenges, remains unclear ...with type 2 diabetes had an increased risk of depressive symptoms, whereas, ...

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Early life stress induces type 2 diabetes at adulthood in male mice

Early life stress induces type 2 diabetes at adulthood in male mice

... induces type 2 diabetes at adulthood in male mice Hanna Ilchmann, Maiwenn Olier, Corinne Lencina, Sandrine Ellero-Simatos, Michèle Nankap, Ambre Riba, Caroline Sommer, Hervé Guillou, Laurence ...

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