tumour growth
The dual effect of MSCs on tumour growth and tumour angiogenesis.
... the tumour vasculature, characterised by a decrease in the number of blood vessels and an increase in the vessel size, leading to a more structured vascular ...poor tumour oxygenation ...B16 tumour ...
13
Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth.
... Received and Revised May 12, 2009; Accepted May 13, 2009 ABSTRACT The development of short interfering RNA (siRNA), has provided great hope for therapeutic targeting of specific genes responsible for patholological ...
12
Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers.
... l(3)mbt tumour suppressor in Drosophila, has revealed predominant expression of germline specific transcripts some of which were found to be essential for tumour growth (Janic et al, ...
17
3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo
... affected tumour growth. It reduced both the incidence and the growth of tumour induced by HT1080 cell ...the growth of more aggressive breast adenocarcinoma MDA- MB231 derived ...
12
TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases 1 development in osteosarcoma model 2 3
... delayed tumour growth in vivo associated with an increase of apoptosis and DNA damage as shown by higher expression level of toxic 8-oxo-G and g H2AX after TH1579 ...primary tumour compared to ...
14
On the importance of the submicrovascular network in a computational model of tumour growth.
... the tumour evolution have been tested in the two tissue cases ...of tumour growth behaviours that can be ...the tumour evolution remains mainly directed by the intrinsic properties of the cell ...
47
Aspartate is an endogenous metabolic limitation for tumour growth
... affects growth of tumours derived from cancer cells of different tissue origins and ...increased tumour growth in HCT116 and AL1376 derived tumours, but not AsPC-1-derived tumours, suggesting that ...
21
On the Incompressible Limit for a Tumour Growth Model incorporating Convective Effects
... A more complete picture is available if the cells do not avoid overcrowding due to Darcy’s law but if they move according to Brinkman’s law. Coupling the cell’s ‘velocity’ to the pressure accounts for visco-elastic ...
34
Tumour growth and drug resistance: an evolutionary view with perspectives in therapeutics
... SCOPE OF THIS REVIEW We focus on intra-tumour hetero- geneity, namely between-cell variability within cancer cell popu- lations, to account for drug resistance. To shed light on such het- erogeneity, we review ...
2
The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.
... and tumour growth in vivo on the chorio-allantoic membrane ...and tumour growth was addressed in vivo using the experimental glioma assay developed on the chicken CAM, as previously described ...
20
TGFBI modulates tumour hypoxia and promotes breast cancer metastasis
... decreases tumour growth and invasion [47] ...to tumour progression [48] ...a tumour-promoting role of TGFBI, but they indicate that modulating TGFBI in breast cancer cells does not directly ...
13
When, why and how tumour clonal diversity predicts survival
... three-dimensional tumour, the endpoint size of one million cells is unrealistically ...make tumour growth even more deterministic and more ...slower growth of especially heterogeneous tumours ...
12
Effective interface conditions for a model of tumour invasion through a membrane
... effective interface, ˜ Γ 1,3 , separates the two limit domains, ˜ Ω 1 , ˜ Ω 3 . Motivations and previous works. Nowadays, a huge literature can be found on the mathe- matical modeling of tumour growth [ 6 , ...
24
Immunomodulatory and antitumour effects of abnormal Savda Munziq on S180 tumour-bearing mice.
... fur; tumour growth incubation period (TT) was 3 days, tumour growth velocity (TS) was slower than in the model ...enlarged tumour, gloomy and unclean fur, and listlessness; TT was 2d, ...
8
Oxidative stress promotes myofibroblast differentiation and tumour spreading
... in tumour growth and metastatic spread, mostly through its role in chemoattraction (Muller et al, 2001; Ostman & Augsten, ...CXCR4-positive tumour cells are attracted to CXCL12-expressing ...
21
1‐ and 2‐Photon Phototherapeutic Effects of Ru(II) Polypyridine Complexes in the Hypoxic Centre of Large Multicellular Tumour Spheroids and Tumour‐Bearing Mice
... their tumour growth monitored (Figure ...weak tumour growth inhibition effect in the dark similar to cisplatin at 10 μM while 1a and 2a did not significantly influence the tumour ...
26
Beyond the tumour microenvironment
... promote tumour progression and has even been included in the 2000s among the ‘hallmarks of ...that tumour eradica- tion after immunotherapy requires immune activation in the ...
9
De-[Constructing] Growth
... While cultural changes (i.e., demand) are needed, fundamental changes in law are indispensable to achieving degrowth and growth where it is needed. These changes include reforms to the financial system (credit, ...
3
Radiation doses from 161Tb and 177Lu in single tumour cells and micrometastases
... single tumour cell, and to the nucleus of any cell in a small cluster, is always higher with 161 Tb than for 177 Lu, regardless of the dis- tribution of the ...
10
De-[Constructing] Growth
... While cultural changes (i.e., demand) are needed, fundamental changes in law are indispensable to achieving degrowth and growth where it is needed. These changes include reforms to the financial system (credit, ...
3