Tumor stroma
Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer
... 31. Tchou J, Conejo-Garcia J. Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma- centric paradigm. Adv Pharmacol. ...
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Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts
... specific signaling exchanges with their stroma, a broad homoge- neity among all samples can be observed in some major tumor- stroma pathways (e.g., HGF, IGF, and Hedgehog). Despite the PDX being ...
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Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment
... specific tumor region surrounded by a separate ECM-filled entity (stromal region) permitting a juxtaposition of different ECM or cell mixtures ...heterogeneous tumor-stroma ...adjacent tumor ...
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Regulation of tumor-stroma interactions by the unfolded protein response
... While tumor-promoting chemicals and oncogenes inhibit GJIC, anti-tumor chemicals and anti-oncogene drugs were associated with growth control and loss of tumorigenicity by re-gaining GJIC activity ...as ...
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Régulation des réponses effectrices des lymphocytes T par les cellules du stroma tumoral
... of tumor associated ...ovarian tumor stroma raises the question whether Hospicells interfere with the responses of T lymphocytes and contribute to immune escape of ovarian cancer ...
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The Role of Stroma in Breast Carcinoma Growth in Vivo
... intratumoral stroma. The clinical significance of the complex changes in tumor stroma remains ...represents tumor encapsulation and a host defense ...with tumor cells, the stroma ...
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en fr Role of stroma and Wound Healing in carcinoma response to ionizing radiation Rôle du stroma et la cicatrisation en réponse de carcinome à des rayonnements ionisants
... of tumor cells and fibroblasts abrogate migration of tumor ...that tumor/stroma interactions would stimulate metastasis after ...as stroma is never irradiated alone but on the contrary ...
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Stellate cells and the development of liver cancer: Therapeutic potential of targeting the stroma
... 11 stages TGF acts as a potent inducer of HSC activation and fibrogenesis but also exhibits growth-inhibitory and apoptosis-inducing effects, and in advanced stages TGF promotes HCC/ICC tumor cell invasion, ...
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Proposal of a hybrid approach for tumor progression and tumor-induced angiogenesis
... towards tumor, how is diffused from vessels to tumor, how tumor cells may control blood flow and oxygen delivery, among ...from tumor cells may enhance tube formation capac- ity of that ...
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Mathematical modeling of liver tumor
... treated tumor nodules in the multi-lobule ...considered tumor cells as not adhesive (Hertz force) while (healthy) hepatocytes were assumed to be adhesive and modeled by the JKR- ...the tumor is ...
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Calpains: Markers of tumor aggressiveness?
... Indeed, in all cell lines, the determination of migration velocities showed that RMS migrated faster and further away than LHCN-M2. The high migration velocities of RMS cells linked to the high invasive behavior of these ...
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Tumor Immunotargeting Using Innovative Radionuclides
... monitoring tumor response by measuring early changes in biomarker expression before being detected using MRI or CT ...assess tumor characterization (as metabolic volume, uptake variations or ...
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CD8+ Tumor-Infiltrating T Cells Are Trapped in the Tumor-Dendritic Cell Network
... massive tumor infiltration, OTI T cells were unable to fully reject the tumor after chemotherapy, we characterized the myeloid cell compartment within the ...tumor. Tumor infiltrating CD11b + ...
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IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
... R ESULTS CXCL12 is upregulated within FL stromal cell niches To decipher the driving signaling involved in the recruitment and homing of malignant FL B cells to their supportive cell niche, and given the key role of ...
31
Translationally Controlled Tumor-Associated Protein
... in tumor reversion, the rare event leading to tumor regression and a “miraculous” cure; is TCTP involved in gene regulation or rather modification of the cytoskeleton of cancer cells during this process? It ...
3
Adaptive dynamics of hematopoietic stem cells and their supporting stroma: A model and mathematical analysis
... Let us briefly sum up the meaning of our assumptions. From a biological point of view, the healthy HSCs cannot proliferate without support cells while cancer cells persist even without support cells. In our model n h (t, ...
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Ontogeny of Tumor-Associated Macrophages
... the tumor microenvironment in most ...the tumor microenvironment and their implication in therapy ...the tumor microenvironment than once thought and raise the question of their respective ...
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Tumor Stiffening, a Key Determinant of Tumor Progression, is Reversed by Nanomaterial-Induced Photothermal Therapy.
... the tumor microenvironment in a spatiotemporal-controlled manner and synergistically with ...of tumor stiffness as well as tumor integrity and progression, under the effect of mild hyperthermia and ...
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Acoustic separation of circulating tumor cells
... circulating cancer cells | cell separation | rare-cell sorting | acoustic tweezers | microfluidics C irculating tumor cells (CTCs) serve as a liquid biopsy target for cancer diagnosis, genotyping, and prognosis ...
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Rheology and Magnetolysis of Tumor Cells
... Due to their spindle-type morphology and gold passivation, magnetic Fe@Au NPs may have a tremendous potential for cancer therapy thanks to tumor cell magnetolysis process (52,53) provided that biocompatibility as ...
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