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treatment efficacy

Development of the Sjögren Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy

Development of the Sjögren Syndrome Responder Index, a data-driven composite endpoint for assessing treatment efficacy

... Discussion Our post hoc analysis of TEARS study data identified five outcome measures that were significantly improved by rituximab compared with a placebo in patients with pSS. Combining these five outcome measures ...

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Open Access to the Resource of Antibiotic Treatment Efficacy Subject to Bacterial Resistance

Open Access to the Resource of Antibiotic Treatment Efficacy Subject to Bacterial Resistance

... The purpose of this paper is to examine how bacterial resistance with respect to a class of antibiotics evolves, when there is open access on behalf of antibiotic producers to the common pool of antibiotic ...

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Comparison of two non-invasive 2% enilconazole infusion protocols for treatment of canine sinonasal aspergillosis and importance of debridement for treatment efficacy.

Comparison of two non-invasive 2% enilconazole infusion protocols for treatment of canine sinonasal aspergillosis and importance of debridement for treatment efficacy.

... Internal Medicine of companion animals, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Belgium. Non-invasive topical infusion therapies are widely used in canine sinonasal ...

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Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

... reductive treatment, the hydrogenated DND (H-DND) can be dispersed in water, and acquire a positive surface charge characterized by a zeta potential of ≈+50 mV [ 15 ...

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Proton MR Spectroscopy for Diagnosis and Evaluation of Treatment Efficacy in Parkinson Disease

Proton MR Spectroscopy for Diagnosis and Evaluation of Treatment Efficacy in Parkinson Disease

... rodegenerative disorder charac- terized by the degeneration of dopaminergic neurons inside the sub- stantia nigra pars compacta, leading to the appearance of motor disorders (1). Diagnosis of PD is still reliant on ...

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Treatment efficacy of DNA lipid nanocapsules and DNA multimodular systems after systemic administration in a human glioma model

Treatment efficacy of DNA lipid nanocapsules and DNA multimodular systems after systemic administration in a human glioma model

... Materials and methods Preparation of nanocarriers Plasmids, lipids for liposome preparation and steric stabilisers The pGWIZ ™ -luciferase DNA plasmid (Gene Therapy systems, Inc., San Diego, CA, USA) was used for DNA ...

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Estimation of an optimal spectral band combination to evaluate skin disease treatment efficacy using multi-spectral images

Estimation of an optimal spectral band combination to evaluate skin disease treatment efficacy using multi-spectral images

... cheek and the vehicle on the other. To this end patients are selected to have the same hyper-pigmentation severity on the two cheeks. Then severity measurements are taken at differ- ent time t along the treatment ...

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The fecal presence of enterotoxin and F4 genes as an indicator of efficacy of treatment with
colistin sulfate in pigs

The fecal presence of enterotoxin and F4 genes as an indicator of efficacy of treatment with colistin sulfate in pigs

... Discussion In this study, the fecal presence of genes encoding STa, STb, LT, F4 and F18 in pigs challenged with an ETEC: F4 strain was determined in order to follow the fecal ETEC population, as an indicator of oral CS ...

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Efficacy of shared decision-making on treatment adherence of patients with bipolar disorder: a cluster randomized trial (ShareD-BD)

Efficacy of shared decision-making on treatment adherence of patients with bipolar disorder: a cluster randomized trial (ShareD-BD)

... in treatment decision-making [ 16 ...BD treatment in clinical ...the efficacy of SDM on quality of care and, more spe- cifically, on treatment adherence and prognostic in ...

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Biomarkers of prognosis and efficacy of treatment

Biomarkers of prognosis and efficacy of treatment

... Process of soluble biomarkers development SURROGATE Qualification Validation Discovery Brain/OMICS technics Analytical performance of assay Assessing clinical value.. OA Biomarkers lymp[r] ...

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Acceptance and efficacy of a guided Internet self-help treatment program for obese patients with binge eating disorder

Acceptance and efficacy of a guided Internet self-help treatment program for obese patients with binge eating disorder

... Recruitment Forty-two patients were recruited from November 2007 to January 2009 from the University Hospitals of Geneva (Switzerland) adult obesity program, a two year multi- disciplinary weight loss treatment ...

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Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs

Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs

... All other parameters were considered secondary. The four clinical parameters assessed by the investigators and the blood parameters were analyzed using a general linear repeated measure mixed model analysis of variance, ...

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FOLFIRI(R) and Bevacizumab in first-line treatment for colorectal cancer patients: safety, efficacy and genetic polymorphisms.

FOLFIRI(R) and Bevacizumab in first-line treatment for colorectal cancer patients: safety, efficacy and genetic polymorphisms.

... Results Patient characteristics Sixty-two patients were enrolled in this trial between January 2007 and August 2009 (Table 1). One patient who had been treated 2 years earlier for a squamous cell vocal cords tumor was ...

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Efficacy of dual carbapenem treatment in a murine sepsis model of infection due to carbapenemase-producing Acinetobacter baumannii

Efficacy of dual carbapenem treatment in a murine sepsis model of infection due to carbapenemase-producing Acinetobacter baumannii

... vivo efficacy of a dual carbapenem combination containing imipenem plus mero- penem against carbapenem-resistant Acinetobacter baumannii producing carbapenemases OXA-23 or ...

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Efficacy of a Virus-Like Nanoparticle As Treatment for a Chronic Viral Infection Is Hindered by IRAK1 Regulation and Antibody Interference

Efficacy of a Virus-Like Nanoparticle As Treatment for a Chronic Viral Infection Is Hindered by IRAK1 Regulation and Antibody Interference

... the treatment for chronic viral infections with the objective of replac- ing exogenous IFN-α administration with endogenous IFN-α secretion following systemic PapMV ...that treatment of mice chronically ...

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SAFE study (Safety and efficacy Analysis of FRED Embolic device in aneurysm treatment): 1-year clinical and anatomical results

SAFE study (Safety and efficacy Analysis of FRED Embolic device in aneurysm treatment): 1-year clinical and anatomical results

... endovascular treatment for intracranial ...good efficacy of this treatment with variable safety ...and efficacy analysis of FreD embolic device in aneurysm ...

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Antibiotic efficacy — context matters

Antibiotic efficacy — context matters

... Extracellular metabolites Environmental nutrients affect many aspects of bacterial physiology that alter antibiotic efficacy, including growth kinetics and stress response activation [ 73,74 ]. Recent studies ...

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Efficacy and stability of orofacial myofunctional therapy on restoring mature pattern of swallowing and nasal breathing in children before orthodontic treatment

Efficacy and stability of orofacial myofunctional therapy on restoring mature pattern of swallowing and nasal breathing in children before orthodontic treatment

... In the present study, several factors could have altered the results, one of which was the restricted number of patients. The strict inclusion and exclusion criteria, the lack of time available to see patients, and the ...

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Impact of the M184V/I Mutation on the Efficacy of Abacavir/Lamivudine/Dolutegravir Therapy in Human Immunodeficiency Virus Treatment-Experienced Patients

Impact of the M184V/I Mutation on the Efficacy of Abacavir/Lamivudine/Dolutegravir Therapy in Human Immunodeficiency Virus Treatment-Experienced Patients

... in treatment-experienced patients due to its high resistance barrier [ 5 , 6 ...in treatment-experienced patients was shown to be noninferior for the maintenance of viral suppression when compared to ...

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Using Bayesian statistics to estimate the likelihood a new trial will demonstrate the efficacy of a new treatment

Using Bayesian statistics to estimate the likelihood a new trial will demonstrate the efficacy of a new treatment

... experimental treatment is superior to the control treat- ment given the evidence accumulated so far?”; the second is “what is the likelihood that a new trial, given some de- sign parameters and previous evidence, ...

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