Transforming Growth Factor b
Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.
... 80s, Transforming Growth Factor-b (TGF-b) has emerged as a family of growth factors involved in essential physiological processes, including embryonic development, ...
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Transforming growth factor-beta and fibrosis.
... Abstract Transforming growth factor-β (TGF-β), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and ...
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Transforming Growth Factor Beta 1 Activation, Storage, and Signaling Pathways in Idiopathic Pulmonary Fibrosis in Dogs.
... Transforming growth factor b1 is produced as an inactive form, the small latent complex, which is the active mature TGF-b1 peptide bound to its propep- ...
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Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-β type II receptor (sTGFβRII) gene transfer
... human corneal fibroblasts, and (ii) whether the nanoparticle-mediated soluble extracellular domain of the transforming growth factor–β type II receptor (sTGFβRII) gene therapy could be [r] ...
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Platelet transforming growth factor-β1 induces liver sinusoidal endothelial cells to secrete interleukin-6
... 5. Transforming growth factor β1 is a strong candidate to activated platelet releasate soluble ...medium. B: Using anti-human TGF-β1, we were able to reduce the effect of APR or recombinant ...
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en fr Role of the small heat shock protein alphaB-crystallin in pulmonary fibrosis and its implication in the signaling pathway of the Transforming Growth Factor béta1 Rôle de la petite protéine de choc thermique alphaB crystallin dans la fibrogénèse pulmonaire et son implication dans la voie de signalisation du transforming growth factor - béta1
... Si l’origine directe de la FPI reste encore un mystère pour les chercheurs, les principaux acteurs conduisant à l’établissement de fibroses pulmonaires chroniques sont bien identifiés. Les myofibroblastes sont ...
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The role of transforming growth factor-beta 1 in steroidogenesis, cell proliferation, and apoptosis in cultured bovine granulosa cells
... Title: Transforming growth factor-~ 1 inhibits luteinization and promotes apoptosis in bovine granulosa cens ... TGF -~ 1 influence on steroidogenesis in cultured bovine gra[r] ...
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Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.
... novel growth factor (GF) cocktail comprising of transforming growth factor (TGF)- β1, bone morphogenetic protein (BMP)2, growth differentiation factor (GDF)5, BMP6, and ...
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Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.
... Transforming Growth Factor-  and Interleukin-1 Signaling Pathways Converge on the Chemokine CCL20 Promoter * Received for publication, December 6, 2014, and in revised form, April 24, 2015 ...
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Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia
... * jingpingge@gmail.com Abstract Diamond Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome with clinical features of red cell aplasia and variable developmental abnormalities. Most affected patients have ...
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Diagnostic value of interleukine-6, transforming growth factor-beta 1 and vascular endothelial growth factor in malignant pleural effusions.
... regulates B cell and T cell function and is a potent inducer of the acute-phase protein ...19,20,25 Transforming growth factor-beta 1 (TGF-β1) is a multifunctional cytokine that stimulates ...
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Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression
... that transforming growth factor- 1 is not only overex- pressed in metaplastic tissues but also reduces E-cad- herin expression in keratinocytes in vitro by inducing the promoter activity of Slug and ...
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Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment
... of transforming growth factor- β (TGF-β) in ...platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) ...
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Controlled Delivery of Transforming Growth Factor β1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling
... deliver transforming growth factor b1 (TGF-b1) to en- capsulated bone-marrow-derived stromal cells (BMSCs) for cartilage tissue engineering applications using two different approaches: (i) ...
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Transforming growth factor-β1 is the predominant isoform required for breast cancer cell outgrowth in bone
... Transforming growth factor (TGF)-b signaling is a potent modulator of the invasive and metastatic behavior of breast cancer cells. Indeed, breast tumor responsiveness to TGF-b is ...
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Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma
... 1.3. Targeted Therapies Although significant progress in understanding the molecular basis of CCA pathogenesis has been achieved, there is no approved molecular targeted therapy that significantly improves patient ...
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Rôle du facteur de croissance transforming growth factor beta-1 (TGF[beta]1) dans la synthèse d'oestradiol par les follicules ovariens bovins
... Rôle du facteur de croissance transforming growth factor beta- 1 (TGF3 1) dans la synthèse d’oestradiol par les follicules ovariens bovinsG. par Yan Ouellette.[r] ...
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[Transforming growth factor-betas: smad signaling and roles in physiopathology]
... le Transforming Growth Factor- (TGF- ) est apparu comme un facteur de croissance impliqué dans des processus physiologiques essentiels comme le développement embryonnaire, la réparation ...
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Glycoproteomic analysis of two mouse mammary cell lines during transforming growth factor (TGF)-Beta induced epithelial to mesenchymal transition
... Peptide identification by LC-MS/MS and database searching Peptides were identified by LC-MS/MS on either a Q-TOF Ultima (Waters) or LTQ XL (Thermo) mass spectrometer. The Q-TOF Ultima was run using the LC setup described ...
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Opposite Effects of Transforming Growth Factor-β Activation and Rho-Associated Kinase Inhibition on Human Trophoblast Migration in a Reconstituted Placental-Endometrial Coculture System
... After uterine evacuation, placentas were immediately collected in DMEM supplemented with heat-inactivated FBS 10%, penicillin (200 U/ml), streptomycin (200 "g/ml), fluconazole (4 "g/ml; Pfizer, Sandwich, UK), and ...
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