tissue factor pathway inhibitor
Genetic variation 25.1 Mb upstream of tissue factor pathway inhibitor is associated with TFPI plasma levels and venous thromboembolism
... plasma tissue factor and tissue factor pathway inhibitor for cardiovascular death in patients with coronary artery disease: the AtheroGene ...
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Expression and methylation status of tissue factor pathway inhibitor-2 gene in non-small-cell lung cancer
... potent inhibitor of plasmin within the ECM is tissue factor pathway inhibitor-2 (TFPI-2), also called matrix- associated serine protease inhibitor ...
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Longer procoagulant phospholipid-dependent clotting time, lower endogenous thrombin potential and higher tissue factor pathway inhibitor concentrations are associated with increased VTE occurrence in patients with newly diagnosed multiple myeloma: results of the prospective ROADMAP-MM-CAT study
... Venous thromboembolism (VTE) is a common complication in newly diagnosed symptomatic multiple myeloma (NDMM) patients. We explored cellular and plasma hypercoagulability in NDMM patients to identify relevant biomarkers ...
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Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells
... signaling pathway involving mechanotransducers such as ion channels, integrins, or G protein-coupled ...AHR inhibitor CH223191, a ligand selective AHR antagonist, which preferentially inhibits some classes ...
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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
... this tissue ( ...JAK/STAT pathway, and consequently through increasing the expression of SOCS2, which is a known inhibitor of the insulin receptor, and increasing the activity of Stat5 signaling up ...
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Regulation of Neuroinflammation: What Role for the Tumor Necrosis Factor-Like Weak Inducer of Apoptosis/Fn14 Pathway?
... sis factor (TNF)-like weak inducer of apoptosis (TWEAK) plays a dual role in the physiological versus inflammatory pathological responses of tissues, including the CNS ( 12 – 15 ...
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Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib
... afenib activates NF-κB signaling pathway by stimu- lating TNFα secretion by treated melanoma cells themselves, leading to autocrine TNF α signaling. Other reports showed that paracrine signaling derived from the ...
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Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin fromEutypa lata, in grape cell tissue cultures
... anthocyanin pathway genes examined, except the UFGT gene, were expressed at the same level at days 3 and 7 in the grapevine ...biosynthetic pathway has been suggested (Boss et ...
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Activation of the Nuclear Factor κB pathway by heavy ion beams of different linear energy transfer
... Heavy ion-induced Nuclear Factor kB activation 3 Materials and methods Cell culture The cell line HEK 293 was established by Graham et al. (1977) from human embryonic kidney cells immortalized by trans- fection ...
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Small-molecule inhibitors of the pseudaminic acid biosynthetic pathway : targeting motility as a key bacterial virulence factor
... https://doi.org/10.1128/AAC.03858-14 Access and use of this website and the material on it are subject to the Terms and Conditions set forth at Small-molecule inhibitors of the pseudaminic acid biosynthetic ...
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Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs
... Our understanding of how DNA methylation impacts gene expression has greatly expanded from the early paradigm that methylation of CpG islands in gene pro- moters inhibits gene expression. It is both novel and surprising ...
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Quantitative characterization of tissue microstructure in concentrated cell pellet biophantoms based on the structure factor model
... the tissue under ...structure factor model (SFM) to take into account coherent scattering from dense concentration of ...characterize tissue from ultrasound ...
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CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice
... Initially investigated for its antiviral properties, DZNep has also demonstrated antitumoral activity [6]. It induces apoptosis, inhibits cell invasion, enhances chemotherapeutic sensitivity in tumor cells but not in ...
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Kinetics of Interaction between ADP-ribosylation Factor-1 (Arf1) and the Sec7 Domain of Arno Guanine Nucleotide Exchange Factor, Modulation by Allosteric Factors, and the Uncompetitive Inhibitor Brefeldin A.
... interactions.Arf1 is found in all eukaryotes examined to date (16) and a physiological role in cell migration and in breast cancer progression has been recently reported (17). The GDP/GTP nucleotide exchange of Arf1 is ...
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Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin from Eutypa lata, in grape cell tissue cultures
... anthocyanin pathway genes examined, except the UFGT gene, were expressed at the same level at days 3 and 7 in the grapevine ...biosynthetic pathway has been suggested (Boss et ...
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Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial-mesenchymal transitions and facilitates early metastasis
... Received: 12 July 2019 / Revised: 18 February 2020 / Accepted: 21 February 2020 / Published online: 10 March 2020 © The Author(s) 2020. This article is published with open access Abstract Epithelial –mesenchymal ...
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Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach
... adipose tissue accumulation (Balage et ...adipose tissue content suggesting an age-related effect of leucine supplementation: decreased overall glucose tolerance in young ...
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Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activities
... Abstract Tissue inhibitor of metalloproteinases-1 (TIMP-1) regulates the extracellular matrix turnover by inhibiting the proteolytic activity of matrix metalloproteinases ...
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Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells.
... TF pathway with TF-antibodies or TF inhibitors accordingly represents today a promising alternative therapeutic strategy for cancer patients to the use of global anticoagulants, the routine ...
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