Structure-Function studies
Structure-function studies of the Kir6.2 channel and of its coupling with natural and artificial partners
... crystal structure of ...crystal structure shows an erroneous interaction due to crystal ...crystal structure is inaccurate to display the real interaction between N-ter and C-ter domains of ...
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Genomics and structure/function studies of Rhabdoviridae proteins involved in replication and transcription.
... and structure of viral biodiversity in this key vector species, as well as the mode and timescale of its evolution, have only been studied on a limited geographical ...phylogeographic structure revealed ...
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Structure-function studies of human ribosome complexes
... per frame in combination with a high-sensitivity and low readout noise pixel detector (Pilatus). In conclusion, the crystals are of excellent quality and diffraction data could be collected and processed, providing a ...
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Structure-function insights into elusive Mycobacterium tuberculosis protein Rv1916
... or function has been reported for the later and therefore, in vivo existence of Rv1916 is ...for structure function studies. The studies categorically demonstrate that akin to Mtb ICL1, ...
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Precision determination of the neutron spin structure function $g^{n}_{1}$
... The fraction of DIS events that come from polarized 3 He as compared to the full target cell is called the dilution factor. It was determined from known unpo- larized nucleon structure functions, measured glass ...
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Structure and function of polycystins: insights into polycystic kidney disease
... divalent cations, including Ca 2+ and Ba 2+ 39 (FIG. 4d). When PC2 is overexpressed in the LLC-PK1 kidney proximal tubule cell line, vasopressin-induced calcium responses are greatly enhanced, whereas the pathogenic ...
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Root structure - function relationships: evidence of a root economics spectrum?
... complementary studies, an experiment on fine roots of 74 herbaceous species from Temperate, Mediterranean, Tropical and sub Tropical sites and a meta-analysis reviewing root traits on 1700 taxa ...
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Combinatorial structure and function studies
... Recursive Ensemble Mutagenesis (REM) was conceived (Arkin and Youvan, 1992) as a way to isolate from a random library many different functional proteins by a more [r] ...
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A Unified Framework for Multimodal Structure-function Mapping Based on Eigenmodes
... 4.3 Structure–function mapping Figure 3 illustrates the NMSE and correlation for the single–subject stategy of Eq. (1). The mappings of Table 1 involving the mean ¯ F are omitted because only a single ...
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New insight into the structure and function of Hfq C-terminus
... 894) at 40 000 × (nominal magnification, the corresponding pixel size was 0.32 nm). FTIR spectroscopy analysis of HfqCTR p Infrared absorption measurements have been performed in the region between 4000 and 400 cm − 1 ...
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Structure and function of the Toscana virus cap-snatching endonuclease
... Finally, several mutations of the N terminal tail were in- troduced in the L protein; the first 5 and 10 amino acid residues were either deleted (Ndel5 and 10) or substituted by a scrambled (same amino acid composition ...
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Structure-function relationships of the lysine decarboxylase from Pseudomonas aeruginosa
... the CheY-related SCOP-fold family, which is characterized by a five-stranded parallel β-sheet sandwiched between two sets of amphipathic α-helices. The linker region consists of a short helical bundle ( α5 – η2 – α6 – ...
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Structure-function strategies to improve the pharmacological value of animal toxins.
... set of characteristics. A rationale structure-function strategy is therefore a key step to obtain a valuable compound for any given application. Strategies are now numerous and have proven to be efficient ...
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Structure, function and assembly of the long, flexible tail of siphophages
... 3. Auzat I, Petitpas I, Lurz R, Weise F, Tavares P: A touch of glue to complete bacteriophage assembly: the tail-to-head joining protein (THJP) family. Mol Microbiol 2014, 91:1164–1178. 4. Zivanovic Y, Confalonieri F, ...
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Structure and Function of Intra–Annual Density Fluctuations: Mind the Gaps
... Battipaglia et al. Intra-Annual Density Fluctuation IADF FORMATION AND POSITION Intra-Annual Density Fluctuations (IADFs) are variations in wood density that are defined by the presence of earlywood-like cells within ...
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Structure, Function, and Evolution of the Pseudomonas aeruginosa Lysine Decarboxylase LdcA
... The only enzyme responsible for cadaverine production in the major multidrug-resistant human pathogen Pseudomonas aeruginosa is the lysine decarboxylase LdcA. This enzyme modulates the general polyamine homeostasis, ...
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Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels
... *Corresponding author The conversion of force into an electrical cellular signal is mediated by the opening of different types of mechanosensitive ion channels (MSCs), including TREK/TRAAK K 2P channels, Piezo1/2, ...
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Reducing false positive connection in tractograms using joint structure-function filtering
... Due to igts igll-posed nature, tractooraphy oenerates a sigonigfcant number of false posigtve connectons between braign reoigons [3]. To reduce the number of false posigtves, Daduccig et al. [1] proposed the COMMIT ...
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Pion Structure Function and violation of the Momentum Sum Rule
... contributions as a function of Q 2 . The suppression is clear on Fig. 3 for whatever (finite) value of the cut-off; the curves are even indistinguishable in this case. As we already said, in order to get a ...
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Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells
... Thus, to be effective, cancer treatments should also target cancer stem-like cells, either by killing them or by forcing them to acquire a differentiated state more sensitive to conventional treatments [ 5 , 10 ]. In ...
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