Stem Cells & Regenerative Medicine
Periodontal regenerative medicine using mesenchymal stem cells and biomaterials: A systematic review of pre-clinical studies
... of regenerative treatment of infrabony defects using autologous BMSC, combined with collagen scaffolds enriched with fibrin glue is ongoing (NIH clinical trial registration number: ...
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Magnetic nanoparticles in regenerative medicine: what of their fate and impact in stem cells?
... in regenerative medicine as they can positively drive stem cell differentiation by their simple presence or when used in concert with magnetic biomechanical stimuli, such as compression or stretching ...
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Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes.
... Role of extracellular vesicles released by mesenchymal stem cells in the treatment of. 13[r] ...
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Advances in Regenerative medicine
... HUCB-derived stem cells compared to the control untreated group (Wu et ...HUCB-derived stem cells survived in the host infarcted myocardium and accumulated around arterioles and scattered in ...
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Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances
... angiogenesis, stem cell dif- ferentiation, or disease treatment, bioactive factors need to be released for specific time points at specific ...for cells [ 100 ...
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Computational Modeling and Reverse Engineering to Reveal Dominant Regulatory Interactions Controlling Osteochondral Differentiation: Potential for Regenerative Medicine.
... mesenchymal stem cells undergo ...the cells start to differentiate into chondrocytes and secrete cartilage matrix rich in type II, IX, and XI ...chondrogenic cells continue to proliferate in a ...
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Transgene-free hematopoietic stem and progenitor cells from human induced pluripotent stem cells
... H. Lapillonne et al., Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine. Haematologica. 95:1651-1659 (2010 ). Aknowledgments: We would like to ...
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Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology.
... injured cells, or indirectly, inducing secretion of functionally active mediators by neighboring ...lating stem cell recruitment and proliferation, and reducing oxidative ...
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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome
... 4, NANOG, and SOX2, and progressive upregulation of a cardiac transcription factor, NKX2-5; connexins (GJA1 and GJA5); and a regulator of calcium homeostasis, RYR2, by day 18 (Figure 1A). Similar gene expression pro files ...
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Deconstructing transcriptional heterogeneity in pluripotent stem cells
... of cells colored as grey dots in ED Figure 2B, and ‘Outliers’ indicates the distinct set of 14 cells colored blue in ED Figure ...outlier cells are indicated by dashed ...outlier cells (left), ...
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Definition of quality standards applicable to the purification and the expansion of mesenchymal stem cells for their use in haematopoietic, immunosuppressive and regenerative cellular therapy
... more cells after 5 passages in MSCGM than in α -MEM + 20% ...media cells were tested negative for CD45, strongly positive for CD73 and CD90 antigens and weakly positive for CD105 and CD106 ...the ...
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On the epigenetic origin of cancer stem cells
... 227 Further analyses will be crucial (i) to understand how this 228 potential hierarchy is established and (ii) to discriminate CSC from 229 non- tumourigenic cancer cells based on their epigenetic landscapes. 230 ...
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Targeting Cancer Stem Cells to Overcome Chemoresistance
... cancer cells [ 24 , 25 ] and also in cancer stem cells leading to chemoresistance [ 26 – 28 ...cancer stem cells, especially ABCG2 and ABCB1, is currently used to identify them in the ...
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Mechanosensitiviy of aged muscle stem cells
... endothelial cells and osteocytes, are mechanically loaded by fluid displace- ment in vivo, inducing a shear stress onto these ...bone cells in vitro has been applied to ...
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Stem cells and the circadian clock
... neural stem cells into the cell cycle ( Bouchard-Cannon et ...proliferating cells in the type 1/2a pools in both Per2 and Bmal1 KO ...2b cells, post-mitotic type 3 cells, and newborn ...
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Lipid nanoparticles for the sustained release of miRNA: new perspectives into intervertebral disc regenerative medicine.
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...
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Cell cycle features of primate embryonic stem cells.
... ES cells was calculated by measuring the delay between release from mitotic block and onset of [ 3 H]-thymidine incorporation in synchronized cells ...ES cells precluded large-scale amplification ...
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Characterization of the cardiogenesis of embryonic stem cells
... Effect of Extracellular Matrix Protein and Surface Patterning on Driving Maturing Phenotypes of Isolated Embryonic Stem Cell Derived Cardiomyocytes during Extended Culture**....[r] ...
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Therapeutic application of mesenchymal stem cells in osteoarthritis
... 1. Introduction Diseases affecting the cartilage have an increasing prevalence as people aged or in younger athletes following sport-related injuries. This is related to the poor intrinsic capability of cartilage to ...
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Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis.
... LLC-Luc cells (5610 4 cells) were inoculated alone (n = 30) or mixed with BM-MSC (2,5610 5 cells) (n = ...25). Cells were injected between the skin and cartilage on the dorsal side of each ...
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