Stem-cell niche
The skeletal muscle stem cell niche : defining hierarchies based upon the stem cell marker PW1 to identify therapeutic target cells
... non-satellite cell progenitors into the myogenic lineage through physical and/or molecular paracrine ...muscle stem cell niche is complex and underline the importance of gaining a better ...
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The extraocular muscle stem cell niche is resistant to ageing and disease
... limb muscles. We described recently that satellite cells secrete MST whereas PICs secrete FST ( Mozzetta et al., 2013 ; Formicola et al., under review). The observations and data presented in this study support the ...
9
Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium
... intestinal stem cell niche in ...and stem cells markers gene ...greater cell height and part of them were not ...of stem cells and proliferation markers were very low, while ...
11
Perlecan is required for FGF-2 signaling in the neural stem cell niche
... granule cell layer (GCL) adjacent to the RMS (Supplemental ...granule cell layer (GCL) of the OB displaying NeuN and BrdU staining in WT-Tg and Hspg2 −/− -Tg ...
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Three-dimensional structure of the mammalian limbal stem cell niche
... limbal stem cell (LSC) niche is accepted, precise knowledge of its three- dimensional (3D) architecture remains ...LSC niche was explored on freshly excised and organ-cultured corneoscleral ...
11
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
... carcinoma stem cells to tether monocytes and derived ...in cell culture, we employed a human monocytic cell line THP1 23 ...the stem-like cells for efficient physical interaction with the ...
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Cancer-Stimulated Mesenchymal Stem Cells Create a Carcinoma Stem Cell Niche via Prostaglandin E
... cancer stem cells (CSCs), which coexist as minority populations within tumors together with a majority population of cancer cells that lack tumor-initiating ability ...the stem-cell state (12, ...a ...
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Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche
... SC numbers vary by muscle fiber type, with higher counts present in oxidative compared to glycolytic muscle beds [10]. In line with this, endurance exercise increases SC numbers in mice and humans [11, 12]. The ...
11
Optimizing stem cell culture.
... influence stem cell fate. A third type of stem cells named induced pluripotent stem (iPS) cells is now also ...pluripotent stem cell state by introducing few genes such as the ...
25
ERK1 Regulates the Hematopoietic Stem Cell Niches
... BM niche could explain the defective effects ...in cell types implicated in the regulation of the niche ...BM stem cell niche ...hematopoietic niche homeostasis [41,42], ...
12
Blimp1 Expression Predicts Embryonic Stem Cell Development In Vitro
... germ cell lineage [ 11 ...pluripotent cell lines that are virtually indistinguishable from ESCs [ 12, 13 ], and among all lineages that develop from epiblast, only germ cells regain expression of ...
8
Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation
... (AP) 6 days later. SETa and SETb overexpression increased colony numbers by 2.3-fold and 1.7-fold, respectively ( Figures 3 H and 3I), indicating that SET can impart survival advantage, consistent with its effect on ...
14
The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
... C3LND cell line ( Figures S3 A and ...both cell lines ( Figure S3 D), metastasis development was signifi- cantly accelerated in the C3LND cells, as indicated by bioluminescence quantification ( Figure S3 ...
11
Transcriptional Regulation of the Intestinal Cancer Stem Cell Phenotype
... for cell growth, cell fate decision, development, senescence, aging, DNA dam- age repair, apoptosis and SC self-renewal [49, ...tumor cell growth and is associated with reduc- tion of ...
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Allogeneic hematopoietic stem cell transplantation for T-prolymphocytic leukemia: a report from the French society for stem cell transplantation (SFGM-TC)
... The analysis assessed pre- and post-transplant disease response, OS, PFS, transplant-related mortality (TRM), dis- ease progression, and cumulative incidences of acute and chronic graft-versus-host disease (GVHD). OS and ...
5
Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy
... haematopoietic stem cell transplantation; MNGIE = mitochondrial neurogastrointestinal encephalomyopathy; TP = thymidine phosphorylase Introduction Mitochondrial neurogastrointestinal encephalomyopathy ...
12
The cell-secreted microenvironment : shaping embryonic stem cell self-renewal and differentiation
... important cell signaling proteins are presented from within the extracellular matrix, both in vivo and in ...the cell (Kuhl and Griffith-Cima, ...affects stem cell properties and how signals ...
146
Unrelated donor haemopoietic stem-cell transplantation: ATG or not?
... blood stem- cells from unrelated donors after myeloablative conditioning, it is unclear whether some subgroups of patients do not benefit or even could be harmed by ATLG ...or stem-cell source could ...
2
Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation (HSCT)
... poietic stem cell transplantation (HSCT) in patients for whom conventional myeloablative allogeneic HSCT is associated with unacceptable risks of ...
7
Stem Cell-Like Properties of CK2β-down Regulated Mammary Cells
... In mammary epithelial cells, including MCF10A cells, TGFβ induces an EMT by driving expression of specific transcription factors, such as Snail1, Slug, and Twist. Accumulating evidences also suggest that EMT-induced ...
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