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Serotonin receptors

Activating and Inhibitory Receptors on Mast Cells

Activating and Inhibitory Receptors on Mast Cells

... ITIM-containing receptors of the CD300 family were found to act as potent negative regulators of anaphylaxis and of other FcRI-dependent allergic reactions (Borrego, ...Sphingosine receptors are likely to ...

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Serotonin and the Immune System

Serotonin and the Immune System

... molecular patterns (e.g. peptidoglycans, bacterial lipopolysaccharides-LPS, double-stranded viral RNAs) bind TLRs on antigen-presenting cells, namely, dendritic cells and macrophages. Antigen-presenting cells then ...

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Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences

Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences

... serotonin receptors (Morilak and Frazer ...on receptors distant from synaptic release sites (Bunin and Wightman 1999), and non-vesicular release of neurotransmitters is known to occur in some ...

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Serotonin and Cardiovascular Diseases

Serotonin and Cardiovascular Diseases

... and serotonin. It has long been known that serotonin receptors are involved in pathophysiology of migraine because of its strong contribution to regulation of cerebral vasomotricity (Goadsby, et ...

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Evidence for a control of plasma serotonin levels by 5-hydroxytryptamine(2B) receptors in mice.

Evidence for a control of plasma serotonin levels by 5-hydroxytryptamine(2B) receptors in mice.

... of serotonin are as a neurotransmitter and local hormone in the gastrointestinal tract enterochromaffin cells and pulmonary neuroepithelial ...Blood serotonin, which is concentrated in the platelet-dense ...

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Serotonin: a new hope in Alzheimer's disease?

Serotonin: a new hope in Alzheimer's disease?

... which serotonin receptor subtypes might mediate this ...different receptors that respond to serotonin, all but 5-HT3 receptors are G-protein-coupled receptors ...

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Implication of 5-HT(2B) receptors in the serotonin syndrome.

Implication of 5-HT(2B) receptors in the serotonin syndrome.

... 2B receptors in the serotonin syndrome" which we submit for consideration as a research article to ...The serotonin syndrome occurs in humans after antidepressant overdose or a combination of ...

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General molecular biology and architecture of nuclear receptors.: Transcriptional regulation by nuclear receptors

General molecular biology and architecture of nuclear receptors.: Transcriptional regulation by nuclear receptors

... nuclear receptors. In the case of ligand-activated receptors, AF-1 modifications have generally a tissue-specific modulatory effect on their transcriptional ...

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Positive regulation of raphe serotonin neurons by serotonin 2B receptors

Positive regulation of raphe serotonin neurons by serotonin 2B receptors

... Absence of response to ecstasy, MDMA, in Htr2b 5-HTKO mice To establish putative direct actions of 5-HT 2B receptors on 5-HT neurons, we developed mice with conditional ablation of this receptor gene specifically ...

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Chemokine receptors in allergic diseases

Chemokine receptors in allergic diseases

... Chemokine receptors in atopic dermatitis Atopic dermatitis is the most common skin disease in the world among ...chemokine receptors play crucial roles in this pathol- ogy by recruiting immune cells to the ...

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Platelet serotonin level predicts survival in amyotrophic lateral sclerosis.

Platelet serotonin level predicts survival in amyotrophic lateral sclerosis.

... platelet serotonin levels in ALS patients The demographic data of ALS patients (Table 1) are in close accordance with previous reports thus showing that the patients included in the present study are ...

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Death receptors as targets in cancer

Death receptors as targets in cancer

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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Rat hepatocytes express functional P2X receptors.: Rat hepatocytes express functional P2X receptors

Rat hepatocytes express functional P2X receptors.: Rat hepatocytes express functional P2X receptors

... P2X4 and P2X7 receptors are expressed at high levels in macrophages [1, 19]. The resident liver macrophages, Kupffer cells, have recently been shown to express P2X4 and P2X6 receptors [20]. Although the ...

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A serotonin-induced N-glycan switch regulates platelet aggregation.

A serotonin-induced N-glycan switch regulates platelet aggregation.

... Concurrently, the association between Rab4-GTP and SERT tethers the transporter to an intracellular compartment to prevent further rises in cytoplasmic 5-HT 22,45 . Here, we provide initial evidence for a new mechanism ...

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Mathematical modeling of serotonin compartmentation in normal human platelets

Mathematical modeling of serotonin compartmentation in normal human platelets

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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A specific role for serotonin in overcoming effort cost

A specific role for serotonin in overcoming effort cost

... Previous studies suggest that we should distinguish between acute and chronic effects of SSRIs ( Fischer et al., 2014 ). We did not find an interaction with time in our results but only a main effect of treatment group. ...

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Electrophysiology of ionotropic GABA receptors

Electrophysiology of ionotropic GABA receptors

... transmission, followed by the progressive closure of the chan- nels when protons and GABA are cleared from the synaptic cleft. NMDA, the glutamate receptor mediating most of the excit- atory signals in the central ...

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Dependence receptors: mechanisms of an announced death.

Dependence receptors: mechanisms of an announced death.

... dependence receptors to be integrated within lipid ...dependence receptors DCC and UNC5H2 whose localization on lipid rafts appears to be ligand independent 7 12 6 Lipid raft localization is thus crucial ...

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Implication de "Liver X Receptors" dans la physiopathologie des gonades

Implication de "Liver X Receptors" dans la physiopathologie des gonades

... Huang, The G-Protein-coupled bile acid receptor, Gpbar1 TGR5, negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activate[r] ...

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Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors.: Profiling of estrogen receptors environmental ligands

Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors.: Profiling of estrogen receptors environmental ligands

... ferutinine is a selective activator of ERα and α-ZA activates efficiently both receptors with a slight preference for ERα. The remainder of the compounds can be considered as partial agonists with graded effects, ...

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