Rodent models
Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors
... Correspondence should be addressed to R Habert at Unit of Stem Cells and Radiation, LDG/SCSR/iRCM/DSV, Centre CEA; Email: rene.habert@cea.fr Abstract Fetal testis is a major target of endocrine disruptors (EDs). During ...
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How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men
... volunteers. Rodent models thus roughly predict effect in ...the rodent models do not predict accurately the outcome of intervention studies in humans for all agents, and Min mice do not appear ...
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Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substances
... animal models, mostly rodent models and in vitro systems have been widely used to assess the deleterious effects and to decipher the mechanisms of action of a number of EASs in the academic world and ...
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Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors.
... Correspondence should be addressed to R Habert at Unit of Stem Cells and Radiation, LDG/SCSR/iRCM/DSV, Centre CEA; Email: rene.habert@cea.fr Abstract Fetal testis is a major target of endocrine disruptors (EDs). During ...
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Rodent models in Down syndrome research: impact and future opportunities
... mouse models (Dp1Yey, Ts65Dn and Ts1Cje) (Guedj et ...mouse models and humans, indicating that the disease mechanisms are likely to be similar in both ...mouse models, and this phenomenon may reflect ...
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CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
... Treg control TRAIL-mediated antitumor effect of CTX-BCG treatment in vivo. Numbers indicate the percentage of cells ± SD. Seven days later, mice received the com- bined treatmen[r] ...
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℮-conome: an automated tissue counting platform of cone photoreceptors for rodent models of retinitis pigmentosa.
... Whatever the delivery system used–be it protein injec- tion, viral vector delivery or even by reactivation of the RdCVF promoter in neighboring cells [7,11,12] –this translational research program requires the ...
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Optimizing the phenotyping of rodent ASD models: Enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features.
... such models created and we can now ask which neurobiological domains are altered in a recurrent manner when an ASD gene is ...of rodent models for ...
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Characterizing the dynamic frequency structure of fast oscillations in the rodent hippocampus
... FIGURE 10 | Examples of ripples from the mutually inclusive (A + AF) and mutually exclusive categories (A − AF and AF − A). The order of the traces for each example is (A) Raw LFP, (B) ripple band signal, (C) multi-unit ...
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Morphometric variation in the forest rodent Malacomys edwardsi (Rodentia: Muridae) in Côte d’Ivoire
... this rodent is known to be a very good swimmer (Nicolas & Colyn, 2006) and to be commonest near streams or swampy areas (Happold, ...abundant rodent species in forest habitats (Decher et ...
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Association of rodent-borne Leptospira spp. with urban environments in Malaysian Borneo
... of rodent kidney was homogenized in 600ml of Buffer RLT Plus (Qia- gen) containing 1% β-mercaptoethanol using the TissueLyser II (Qiagen), and a 5mm stainless steel ...
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Rhodamine 800 as a near-infrared fluorescent deposition flow tracer in rodent hearts
... / La version de cette publication peut être l’une des suivantes : la version prépublication de l’auteur, la version acceptée du manuscrit ou la version de l’éditeur. For the publisher’[r] ...
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Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes
... To distinguish between these possibilities, we used likeli- hood methods implemented in the PAML package to detect signatures of positive selection ( Yang 1997 ). Muroideae are an ideal species set for these analyses ...
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The Goto-Kakizaki rat is a spontaneous prototypical rodent model of polycystic ovary syndrome
... However, these approaches have not made it possible to determine the timing of PCOS phenotype development, the precise part played by each actor and the underlying mechanisms. Rather, they highlight the great complexity ...
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The role of sleep in emotional processing: insights and unknowns from rodent research
... conditioning, while inhibiting them promotes contextual fear memory consolidation (Izawa et al. However, it is yet unknown how MCH neurons manipulations affect REM sleep thet[r] ...
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Phylogeography and evolutionary history of Leopoldamys neilli, a Murinae rodent endemic to limestone karsts, in Thailand
... Phylogeography and evolutionary history of Leopoldamys neilli, a Murinae rodent endemic to limestone karsts, in Thailand A. Latinne (1), S. Waengsothorn (2), V. Herbreteau (3), J. R. Michaux (1,4) (1) Institut de ...
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en fr Neuronal properties and synaptic connectivity in rodent presubiculum Propriétés neuronales et connectivité synaptique dans le présubiculum de rongeur
... The electrophysiological and morphological properties of excitatory and inhibitory neurons contained in the six layers of this transitional cortex have been described previously (Abbasi and Kumar, 2013; Simonnet et al., ...
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Technical report 300-QV-13 On 300 MHz quadrature volume coil for rodent imaging in vivo
... The probe for a rodent head in vivo MR imaging incorporates a quadrature inductively coupled volume RF coil. RF resonator (eight element high pass bird cage) is embedded into the shielded matching/tuning assembly ...
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An endogenous gibbon ape leukemia virus (GALV) identified in a rodent (Melomys sp.) from Indonesia
... 22. Benveniste RE, Callahan R, Sherr CJ, Chapman V, Todaro GJ. 1977. Two distinct endogenous 689 type C viruses isolated from the asian rodent Mus cervicolor: conservation of virogene 690 ...
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Co-evolution of the parasitic fungi Pneumocystis and their Muridae rodent hosts in Southeast Asia
... The five remaining lineages may correspond to several new undescribed Pneumocystis species and infect the lungs of Cannomys (lineage 1), Bandicota (lineage 2), Ber[r] ...
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