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RNA-binding protein(s)

Inactivation of the Celf1 gene that encodes an RNA-binding protein delays the first wave of spermatogenesis in mice.

Inactivation of the Celf1 gene that encodes an RNA-binding protein delays the first wave of spermatogenesis in mice.

... Methodology/principal findings: We evaluated the requirement for the RNA-binding protein CELF1 during the first wave of spermatogenesis in mice. Mice inactivated for Celf1 gene were not viable on ...

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Depolarization-induced translocation of the RNA-binding protein Sam68 to the dendrites of hippocampal neurons.

Depolarization-induced translocation of the RNA-binding protein Sam68 to the dendrites of hippocampal neurons.

... the RNA-binding protein hnRNP A1 (Van der Houven van Oordt et ...This protein is predominantly nuclear, but a minority of ZBP2 form clusters in neuronal processes, which are colocalized with ...

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The RNA-Binding Protein RBPMS2 Regulates Development of Gastrointestinal Smooth Muscle

The RNA-Binding Protein RBPMS2 Regulates Development of Gastrointestinal Smooth Muscle

... expression. RNA-protein complexes control multiple steps of this process, including mRNA cellular localization, splicing, translational regulation, or mRNA ...specific RNA-binding proteins ...

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RNA-binding protein Rbm24 as a multifaceted post-transcriptional regulator of embryonic lineage differentiation and cellular homeostasis

RNA-binding protein Rbm24 as a multifaceted post-transcriptional regulator of embryonic lineage differentiation and cellular homeostasis

... Abstract RNA-binding proteins control the metabolism of RNAs at all stages of their ...conserved RNA-binding protein that displays strongly regionalized expression patterns and exhibits ...

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The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages.

The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages.

... rate protein synthesis during germ cell development relies on RNA binding proteins that control the storage, stability, and translation of mRNAs in a tightly and temporally regulated ...the ...

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Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

... Berlin, Germany Colonization of the mosquito host by Plasmodium parasites is achieved by sexually differentiated gametocytes. Gametocytogenesis, gamete formation and fertilization are tightly regulated processes, and ...

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Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

... observed. We analyzed motif overlap with 166 human RBPs in CIS-BP-RNA database 10 and found that about 70 RBPs show a significant competitive or cooperative relationship with motif- overlapping seeds (Fig.2c and ...

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en fr The involvement of the RNA binding protein Staufen 1 in tumoral development and progression Le rôle de la protéine de liaison à l'ARN Staufen 1 dans le développement et la progression tumorale

... 29 nucléases a été réalisé chez la levure. L’initiation de la dégradation de transcrits peut se faire aux extrémités, soit dans le sens 3’5’ ou 5’3’, ou encore par un clivage endonucléique. Pour ne pas être en ...

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The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein

The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein

... unlabeled protein in 50 mM Hepes pH ...labeled RNA oligonucleotides (IDT) at a final concentration of 50 ...gies). Binding isotherms were fitted using the Hill ...

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The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1

The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1

... cAMP-dependent protein kinase (PKA) in the control of TTP family activity in mRNA decay remains largely un- ...and protein phos- ...of proteinprotein interactions between TIS11b and ...

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ALS-associated RNA-binding protein FUS and mRNA translation regulation

ALS-associated RNA-binding protein FUS and mRNA translation regulation

... Studying protein behavior and ALS-linked mutations effect on cellular processes provides insights leading us to better understand the molecular mechanisms causing the ...for RNA-binding proteins and ...

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A crosstalk between the RNA binding protein Smaug and the Hedgehog pathway links cell signaling to mRNA regulation in drosophila

A crosstalk between the RNA binding protein Smaug and the Hedgehog pathway links cell signaling to mRNA regulation in drosophila

... In addition to its role during synaptogenesis, Smaug1 was recently reported to be a key regulator of osteoblastogenesis and bone development by repressing translation of mig6 (mitogen-inducible gene 6) mRNA in mice (Niu, ...

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Purification and identification of specific RNA-binding protein that binds to the 3'UTR region of cytochrome P450aromatase mRNA in bovine granulosa cells

Purification and identification of specific RNA-binding protein that binds to the 3'UTR region of cytochrome P450aromatase mRNA in bovine granulosa cells

... "Regulation of porcine granulosa cell steroidogenic acute regulatory protein (StAR) by insulin-like growth factor 1: synergism with follicle-stimulating hormone or [r] ...

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A strategy to analyze the phenotypic consequences of inhibiting the association of an RNA-binding protein with a specific RNA.: Targeted inhibition of RNA-protein interaction

A strategy to analyze the phenotypic consequences of inhibiting the association of an RNA-binding protein with a specific RNA.: Targeted inhibition of RNA-protein interaction

... Results and discussion To identify the mRNA sequence element in Su(H) mRNA bound by CUGBP1, 5 RNAs corresponding to overlapping regions of the 3' Untranslated Region (3'UTR) were tested by EMSA (Electrophoretic Mobility ...

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Post-transcriptional regulation during spermatogenesis : Role of the RNA-Binding Protein HuR

Post-transcriptional regulation during spermatogenesis : Role of the RNA-Binding Protein HuR

... detail, we analyzed the morphology of testis and epididymis in pre-pubertal and adult HuR tg mice. While progression of spermatogonial and meiotic stages is normal in HuR tg seminiferous tubules, impaired germ cell ...

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miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47

miR-25 Promotes Melanoma Progression by regulating RNA binding motif protein 47

... targets RNA binding motif protein 47 Matured miRNAs are single-stranded RNAs and act through a perfect or near perfect base pairing with the target mRNA 3'-untranslated regions (3'-UTRs), leading to ...

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How bacterial ribosomal protein L20 assembles with 23 S ribosomal RNA and its own messenger RNA.

How bacterial ribosomal protein L20 assembles with 23 S ribosomal RNA and its own messenger RNA.

... upon RNA addition cannot be solely explained by the expected size of this complex (~20 ...The RNA/L20C complexes proved to be sufficiently stable to allow purification as a single symmetric peak by ...

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Post-transcriptional regulatory patterns revealed by protein-RNA interactions

Post-transcriptional regulatory patterns revealed by protein-RNA interactions

... of protein-RNA interactions can provide a better coverage of the protein-RNA interac- tion space and improve our understanding of post-transcriptional ...the RNA regulon theory at ...

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Regulation of the unfolded protein response by noncoding RNA

Regulation of the unfolded protein response by noncoding RNA

... CDKN1B protein levels (25) miR-322 Down PDIA6 Calcium homeostasis Sustained UPR response (35) miR-346 Up TAP1 Airway epithelium Reduced MHC I-associated antigen presentation (7) miR-378a-3p ...

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Identification of giant Mimivirus protein functions using RNA interference

Identification of giant Mimivirus protein functions using RNA interference

... Proteomic Analysis All proteomic analysis (sample preparation, 1D and 2D gel electrophoresis, silver staining, and western blotting) was per- formed as previously described ( Azza et al., 2009 ). Briefly, Mimivirus was ...

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