Rheumatoid arthritis (RA)
Variations in the metabolome in response to disease activity of rheumatoid arthritis
... Keywords: Rheumatoid arthritis, Metabolomics, Anti-TNF-alpha therapy, Drug response biomarkers Abbreviations: ANOVA, Analysis of variance; Anti-CCP, Anti-cyclic citrullinated peptide; CRP, C-reactive ...
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Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis
... Introduction Rheumatoid arthritis (RA) is a destructive, systemic inflammatory and autoimmune disorder that affects up to 1% of the general adult population ...
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Improving risk-stratification of rheumatoid arthritis patients for interstitial lung disease
... Interstitial lung disease (ILD) is the most common pulmonary manifestation of rheumatoid arthritis (RA), occurring in *10% of patients. It has emerged in recent series as a key prognos- tic factor including ...
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Fears and Beliefs in Rheumatoid Arthritis and Spondyloarthritis: A Qualitative Study
... the Rheumatoid Arthritis Impact of Disease (RAID) health profile and the twenty-item Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) questionnaire [ 30 , 31 ...
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Where to Stand with Stromal Cells and Chronic Synovitis in Rheumatoid Arthritis?
... during Rheumatoid Arthritis Progression Epigenetic marks, such as DNA methylation and histone acetylation, are key molecular events that integrate environmental ...
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Could Omega 3 Fatty Acids Preserve Muscle Health in Rheumatoid Arthritis?
... Keywords: rheumatoid arthritis; cardiovascular diseases; muscle; lipids; omega 3 ...Introduction Rheumatoid arthritis (RA) is the most prevalent inflammatory rheumatic disease, affecting ...
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Poor Survival in Rheumatoid Arthritis Associated with Bronchiectasis: A Family-Based Cohort Study
... Abstract Background: Diffuse bronchiectasis (DB) may occur in rheumatoid arthritis (RA). CFTR (cystic fibrosis transmembrane conductance regulator) mutations predispose RA patients to DB, but the prognosis ...
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Sodium excretion is higher in patients with rheumatoid arthritis than in matched controls
... No study has clearly evaluated the influence of rheumatoid arthritis on sodium excretion. Natriuresis may be impacted by inflammatory states only in acute situations. In equilibrate state, when renal and ...
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The Key Comorbidities in Patients with Rheumatoid Arthritis: A Narrative Review
... for Rheumatoid Arthri- tis (BSRBR-RA) demonstrated that treatment with TNF inhibitors significantly reduced the risk of MI compared with csDMARDs, although no differences in MI severity or mor- tality were ...
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Adalimumab alone and in combination with disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis in clinical practice: the Research in Active Rheumatoid Arthritis (ReAct) trial
... Active Rheumatoid Arthritis) study was initiated to assess the safety and effectiveness of adalimumab, a fully human IgG 1 anti-TNF monoclonal anti- body (1) in combination with a variety of DMARDs and ...
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Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis
... We have observed that sera from rheumatoid arthritis (RA) patients recognize the BRAF’s catalytic domain, which encompasses amino acids 416 to 766. Here, we identify peptide targets of anti-BRAF ...
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Mesenchymal Stem Cells Improve Rheumatoid Arthritis Progression by Controlling Memory T Cell Response
... Chile, 3 IRMB, INSERM, Univ Montpellier, Montpellier, France, 4 Cellvax, SAS, Parc BIOCITECH, Romainville, France, 5 Cells for Cells, Universidad de los Andes, Santiago, Chile, 6 Laboratorio de Biología Celular, ...
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Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients.
... ; Arthritis ; Rheumatoid Arthritis ; Osteoarthritis ; inflammation INTRODUCTION Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the synovial ...
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Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis.
... in rheumatoid arthritis (RA); according to this model, RA is associated with the RAA shared epitope sequence (72–74 positions) and the association is modulated by the amino acids at positions 70 and 71, ...
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Association Study of VDR Gene with Rheumatoid Arthritis in the French Population
... Vitamin D is a potent regulator of calcium homeostasis and may have immunomodulatory effects. The influence of vitamin D on human autoimmune disease is controversial. The aim of this study was to investigate the role of ...
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X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis
... Received: 22 August 2016; Accepted: 31 October 2016; Published: 8 November 2016 Abstract: Rheumatoid arthritis (RA) is an autoimmune disease that predominantly affects women. MicroRNAs have emerged as ...
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Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis
... of rheumatoid arthritis (RA), today’s major challenge remains to identify biomarkers to target treatments to selected patient ...and arthritis, and evaluating its predictive value as biomarker for ...
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New autoantibodies in early rheumatoid arthritis.
... Rheumatoid arthritis (RA) is a chronic autoimmune dis- ease affecting 0.5% of the world population. It is character- ized by inflammation of joints that results in cartilage and bone destruction, joint ...
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Definition of B cell helper T cells in rheumatoid arthritis and their behavior during treatment
... Abstract Background: Immunopathogenesis of rheumatoid arthritis (RA) is not yet clearly defined. Besides known B-cell involvement, RA development and evolution involves CD4 + T helper cell homeostasis ...
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New autoantibodies in early rheumatoid arthritis
... Rheumatoid arthritis (RA) is a chronic autoimmune dis- ease affecting 0.5% of the world population. It is character- ized by inflammation of joints that results in cartilage and bone destruction, joint ...
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