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Retinal diseases

Real-world data in retinal diseases treated with anti-vascular endothelial growth factor (anti-VEGF) therapy – a systematic approach to identify and characterize data sources

Real-world data in retinal diseases treated with anti-vascular endothelial growth factor (anti-VEGF) therapy – a systematic approach to identify and characterize data sources

... Background Retinal diseases Retinal diseases, which are often characterized by leak- age of fluid, hemorrhage and fibrous scarring in the eye, include wet age-related macular degeneration ...

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MERTK mutation update in inherited retinal diseases

MERTK mutation update in inherited retinal diseases

... 3 Retinal images illustrating the phenotypic variability of inherited retinal diseases associated with MERTK ...narrowed retinal vessels, a beaten-bronze appearance of the reti- nal periphery ...

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Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases

Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases

... associated with occult macular dystrophy [33]. In our study, this variant did not co-segregate with the pheno- type in other affected family members (data not shown). This NGS study ended with six genetically unresolved ...

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Metabolic and Redox Signaling of the Nucleoredoxin-Like-1 Gene for the Treatment of Genetic Retinal Diseases

Metabolic and Redox Signaling of the Nucleoredoxin-Like-1 Gene for the Treatment of Genetic Retinal Diseases

... that specifically triggers the destruction of the mRNA encoding a class II P23H mutant rhodopsin mRNA [ 36 ]. Hammerhead ribozymes are able to induce site-specific cleavage of RNA, with ribozymes including two different ...

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Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies

Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies

... The retinal cross-sectional images measured by OCT in- struments consist of alternately bright and dark layers because of the different backscattering properties of cells distributed in different morphological ...

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CRB1 mutations in inherited retinal dystrophies.

CRB1 mutations in inherited retinal dystrophies.

... an Illumina GAIIx as paired-end 75 bp reads. Image analysis and base calling was performed using Illumina Real Time Analysis (RTA) Pipeline version 1.10 with default parameters. Sequence reads were aligned to the ...

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Retinal optical imaging of intrinsic signals

Retinal optical imaging of intrinsic signals

... with retinal diseases, they do not provide functional assessments of retinal ...of retinal integrity often requires the use of complementary functional ...study retinal function, both ...

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Neurogenesis and Specification of Retinal Ganglion Cells

Neurogenesis and Specification of Retinal Ganglion Cells

... that retinal progenitor cells in vertebrates can generate different retinal types in a stochastic manner but with a probabilistic bias for some cell types that change during ...all retinal cell types ...

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Retinal Image Quality Assessment Using Supervised Classification

Retinal Image Quality Assessment Using Supervised Classification

... ABSTRACT Retinal image quality assessment is an important step in automated eye disease ...of retinal images, because poor image quality might prevent the observation of significant eye features and disease ...

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Protuberant Electrode Structures for New Retinal Implants

Protuberant Electrode Structures for New Retinal Implants

... 4. Conclusions Focal stimulation is a challenge for neural prostheses and especially for retinal ones. Improvement of the stimulation process can be achieved by modifying several parameters as the type of ...

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Protuberant Electrode Structures for New Retinal Implants

Protuberant Electrode Structures for New Retinal Implants

... (a) (b) Figure 3. (a) Verification of the correct placing of the implant in sub-retinal position two weeks after implantation: Eye fundus of P23H rats with the implant obtained with a Micron III; (b) Confocal ...

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Retinal-inspired filtering for dynamic image coding

Retinal-inspired filtering for dynamic image coding

... 0.3884 Fig. 5: Progressive reconstruction based on ROC model. 6. CONCLUSION In this document, we have introduced a novel non-separable spatiotemporal filter (non-SPAM) based on a retinal model. This filter has a ...

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Serotonin and Cardiovascular Diseases

Serotonin and Cardiovascular Diseases

... Few studies have suggested possibility of a direct SERT modulation in cardiovascular organs. SERT is expressed in many cardiovascular sites, including heart, blood vessels, platelets and bone marrow. SERT is involved in ...

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Infrared laser stimulation of retinal and vestibular neurons

Infrared laser stimulation of retinal and vestibular neurons

... Figure 6. Temperature rise for various pulse durations at maximum and constant optical power for three laser wavelengths. In summary, we have demonstrated that infrared laser radiations provide a possible way for ...

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Segmentation of Retinal Arteries in Adaptive Optics Images

Segmentation of Retinal Arteries in Adaptive Optics Images

... † LTCI, CNRS UMR5141, Institut Mines-Télécom, Télécom ParisTech, Paris, France ‡ CIC 503, Centre Hospitalier National des Quinze-Vingts, Paris, France Abstract—In this paper, we present a method for automatically ...

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Retinal blood vessel segmentation using geodesic voting methods

Retinal blood vessel segmentation using geodesic voting methods

... on retinal blood vessels in particular. We can classify the retinal segmentation method into two categories: supervised methods which re- quire manually labeled images [4] and unsupervised methods [5, ...

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View of Neurological diseases

View of Neurological diseases

... phiques par étude rétrospective des dossiers de patients admis dans un service de réanimation traumatologique de 18 lits, présentant un traumatisme vertébromédullaire de niveau compris[r] ...

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View of Liver diseases

View of Liver diseases

... Cependant, en 2010, cette mortalité reste plus élevée que pour les non cirrhotiques (66 vs 42 %, p < 0,01), et la cirrhose reste un facteur de risque de mortalité chez les malades e[r] ...

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View of Abdominal diseases

View of Abdominal diseases

... monocentrique de l’ensemble des patients ayant été admis dans le ser‑ vice de réanimation hépatique pour une insuffisance hépatique aiguë et répondant aux critères de TH.. Les patients [r] ...

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View of Digestive diseases

View of Digestive diseases

... Patients et Méthodes : Nous avons réalisé une étude rétrospective monocentrique incluant tous les patients d ’oncohématologie (OH) admis dans le service de réanimation médicale de l ’hôp[r] ...

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