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reperfusion injury

Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart

Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart

... coupling [ 35 ] and the downregulation and upregulation of multiple genes, such as Trpc6 or Ryr2, involved in the activity of the sinoatrial node [ 36 ] have been previously reported in GK rats and could explain the ...

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Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non‑obese type 2 diabetic Goto‑Kakizaki rats

Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non‑obese type 2 diabetic Goto‑Kakizaki rats

... ischemia reperfusion (I/R) injury, is a major cause of morbidity and mortality in type 2 diabetic ...ischemia/reperfusion injury for the purpose of ...

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Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats

... This study also suggests that for the same amounts of total fats and saturated fats, the hearts of rats receiving n-3 PUFA were more resistant than those receiving increased amounts of n-6 PUFA. Although the difference ...

9

Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair.

Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair.

... tissue injury such as proximal tubule necrosis and outer medulla congestion occurred during the reperfusion phase following 60 min of ischemia ...ischemia-reperfusion injury, in particular ...

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IL-33 receptor ST2 deficiency attenuates renal ischaemia–reperfusion injury in euglycaemic, but not streptozotocin-induced hyperglycaemic mice

IL-33 receptor ST2 deficiency attenuates renal ischaemia–reperfusion injury in euglycaemic, but not streptozotocin-induced hyperglycaemic mice

... kidney injury; BMI, body mass index; BUN, blood urea nitrogen; GFR, glomerular filtration rate IRI, ischemia-reperfusion injury; HMBS, HydroxyMethylBilane Synthase; HPRT, hypoxanthine ...

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Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor

... Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor... Version postprint.[r] ...

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Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.

Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.

... Ischemia/reperfusion injury occurring during liver transplantation is mainly due to the generation of reactive oxygen species (ROS) upon ...ischemia reperfusion injury when administrated to ...

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Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury

Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury

... Received: 24 April 2016; Accepted: 17 May 2016; Published: 25 May 2016 Abstract: The endoplasmic reticulum (ER) is involved in calcium homeostasis, protein folding and lipid biosynthesis. Perturbations in its normal ...

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Cardiac remodeling and higher sensitivity to ischemia-reperfusion injury in female rats submitted to high-fat high-sucrose diet: an in vivo / ex vivo longitudinal follow-up

Cardiac remodeling and higher sensitivity to ischemia-reperfusion injury in female rats submitted to high-fat high-sucrose diet: an in vivo / ex vivo longitudinal follow-up

... ischemia and mostly reflow are well-known to induce high oxidative stress, which is exacerbated here by the 5-month high-fat high-sucrose diet. We also assessed the S- Glutathionylation of proteins, which is the ...

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Direct intraperitoneal resuscitation with lidocaine, methylene blue and pentoxiphylline combination does not decreases inflammation after intestinal ischemia-reperfusion injury in rats.

Direct intraperitoneal resuscitation with lidocaine, methylene blue and pentoxiphylline combination does not decreases inflammation after intestinal ischemia-reperfusion injury in rats.

... Lidocaine is widely used as a local anesthetic, but has been recently administered systemically in horses to treat post operative ileus. It is known that local anesthetic agents modulate the inflammatory response via ...

5

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury

... 6.1.4. The Effector MLKL Mixed lineage kinase domain-like protein (MLKL) is a protein in the necroptotic signalling cascade, functioning downstream of RIPK3 [ 87 , 88 ]. The MLKL protein contains two domains: a ...

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Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

... why Aag-initiated BER is toxic and Ung/Ogg1/Neil1 initiated repair is not (34–36). We previously observed that Aag −/− mice are more susceptible than WT mice to inflammation-associated colon cancer (12); this may at ...

10

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en fr New mechanisms of protection of cardiomyocytes from ischemia / reperfusion injury Nouveaux mécanismes de protection des cardiomyocytes contre les lésions d'ischémie / reperfusion

... This leads to a reversal of the mitochondrial F1Fo ATP synthase as a way to maintain a potential: the enzyme actively transfers protons from the matrix to the intermembrane space but at [r] ...

150

A novel therapeutic peptide targeting myocardial reperfusion injury

A novel therapeutic peptide targeting myocardial reperfusion injury

... Supplemental Figure S9: Effects of Tat-DAXXp treatment on DAXX phosphorylation. Western blot analysis was performed on LV protein extracts[r] ...

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Acute Induction of Translocon-Mediated Ca2+ Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

Acute Induction of Translocon-Mediated Ca2+ Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

... 49. Sleiman, N.H.; McFarland, T.P.; Jones, L.R.; Cala, S.E. Transitions of protein traffic from cardiac ER to junctional SR. J. Mol. Cell. Cardiol. 2015, 81, 34–45, doi:10.1016/j.yjmcc.2014.12.025. 50. Hajnóczky, G.;  ...

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Rôle de l'alarmine IL-33 dans un modèle murin d'ischémie-reperfusion hépatique

Rôle de l'alarmine IL-33 dans un modèle murin d'ischémie-reperfusion hépatique

... tissue injury, and as a cytokine, contributing to the latter resolutive/repair phase of sterile ...organ injury models, especially ischemia-reperfusion injury, in the kidneys, liver and lungs, ...

193

Devenir de la Na+, K+-ATPase dans l'ischémie reperfusion cardiaque : de sa régulation aux compléments alimentaires

Devenir de la Na+, K+-ATPase dans l'ischémie reperfusion cardiaque : de sa régulation aux compléments alimentaires

... I-R injury was reduced in ␣1-L499V-expressing cells compared with ␣1-ex- pressing ...ischemia-reperfusion injury; oppossum kidney cells; cardiotonic ...

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Successful Controlled Limb Reperfusion after Severe Prolonged Ischemia

Successful Controlled Limb Reperfusion after Severe Prolonged Ischemia

... controlled reperfusion might avoid propagation of thrombus in both the arterial and venous ...However, reperfusion injury has a complex pathophysiologic basis and cannot be used as a synonym for free ...

5

L’ischémie reperfusion - Acteur essentiel du devenir du greffon rénal

L’ischémie reperfusion - Acteur essentiel du devenir du greffon rénal

... Ischemia reperfusion control: the key of kidney graft outcome During the transplantation procedure, ischemia reperfusion is an inevi- table situation characterized by specific pathophysiological processes, ...

6

Renal ischemia/reperfusion decreases the expression of DPP-4

Renal ischemia/reperfusion decreases the expression of DPP-4

... In rat kidneys, mRNA abundance of DPP-4 was significantly decreased following I/R in all group: NR (2,07-fold), 6h (8,12-fold), 24h (12.5-fold) and 48h (12.9-fold). Immunoblotting analyses showed a 1.2-fold reduction of ...

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