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Renal Cell Carcinoma Tumour

Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma

Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma

... In addition the distribution of somatic mutations reveals that the codon 81 has been involved in only one tumour from studies other than those of Brüning et al [20] and Brauch et al. [9]. Overall mutations at this ...

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Computational Modelling of Metastasis Development in Renal Cell Carcinoma

Computational Modelling of Metastasis Development in Renal Cell Carcinoma

... Under such a model, high pressure provokes decreased proliferation, but not apoptosis. Montel et al. suggested that mechanical stresses have a poor effect on apoptosis, but also indi- cated that this could depend on the ...

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Étude de l'expression des kinases Aurora dans le carcinome à cellules rénales. [Study of the expression of Aurora kinases in renal cell carcinoma].

Étude de l'expression des kinases Aurora dans le carcinome à cellules rénales. [Study of the expression of Aurora kinases in renal cell carcinoma].

... [9] Matthews N, Visintin C, Hartzoulakis B, Jarvis A and Selwood DL: Aurora A and B kinases as targets for cancer: will they be selective for tumors? Expert Rev Anticancer Ther. 6: 109-20, 2006. [10] Adams RR, Eckley ...

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A Synchronous Pancreatic Metastasis from Renal Clear Cell Carcinoma, with Unusual CT Characteristics, Completely Regressed after Therapy with Sunitinib.

A Synchronous Pancreatic Metastasis from Renal Clear Cell Carcinoma, with Unusual CT Characteristics, Completely Regressed after Therapy with Sunitinib.

... After the surgery the patient performed two more cycles of Sunitinib, stopped due to poor tolerance, a total of eight cycles were administrated. The following CECT exams showed the outcomes, such as metallic clips, of ...

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Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment.

Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment.

... two cell lines following growth factor treatment and strongly expressed in cell lines displaying endogenous EMT ...colorectal carcinoma cell lines ...hepatocellular carcinoma tissues ...

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Comprehensive molecular characterization of clear cell renal cell carcinoma

Comprehensive molecular characterization of clear cell renal cell carcinoma

... clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, ...with ...

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The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

... submit tumour cells to a significant selective pressure. In fact, tumour cells can develop mechanisms that modulate and/or inhibit the immune response, including: first, the production of immunosuppressive ...

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Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.

Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.

... of cell-to-cell contact inhibition and can grow over one another forming ...induces cell transformation [35,36] while overex- pression of Aurora-B cannot form colonies on soft agar ...stable ...

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Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

... The 4 planar polynomial shape electrodes with a tip-tip spacing of 75μm was fabricated on a quartz wafer by conventional photolithography technique, which generates DEP force to trap cancer cells, then rotates them by ...

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Genome-wide linkage screen for testicular germ cell tumour susceptibility loci.

Genome-wide linkage screen for testicular germ cell tumour susceptibility loci.

... In previous studies we analysed families in a number of pre-specified subgroups based on histology, UDT status, age at cancer onset and bilaterality of cancer. For this analysis we limited the subgroups to bilaterality ...

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Combination lenalidomide-rituximab immunotherapy activates anti-tumour immunity and induces tumour cell death by complementary mechanisms of action in follicular lymphoma

Combination lenalidomide-rituximab immunotherapy activates anti-tumour immunity and induces tumour cell death by complementary mechanisms of action in follicular lymphoma

... of tumour- infiltrating T cells from patients with B-cell lymphoma to form functional immune synapses with autologous malignant B cells (Ramsay et al, 2008, 2009; Hagner et al, ...NHL cell lines (Wu ...

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en fr Role of endothelial and tumor lysyl oxidase like-2 to angiogenesis in clear cell renal cell carcinoma Rôle de la lysyl oxidase-like-2 endothéliale et tumorale au cours de l’angiogenèse dans le carcinome du rein à cellules claires

... 33. A. Galaup, E. Gomez, R. Souktani, M. Durand, A. Cazes, C. Monnot, J. Teillon, S. Le Jan, C. Bouleti, G. Briois, J. Philippe, S. Pons, V. Martin, R. Assaly, P. Bonnin, P. Ratajczak, A. Janin, G. Thurston, D. M. ...

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Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

... Methods Patients Female pts., aged ≥18, with a unilateral breast DCIS, treated at the Jean Perrin Comprehensive Cancer Centre between 2001 and 2005, were retrospectively selected. The pts. with family history of BC, ...

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Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

... Several authors have already addressed the question of stromal lymphocytic infiltrate significance in DCIS with or without microinvasion [ 14 – 18 ]. In the seminal paper on DCIS immunogenicity, Black et al. suggested an ...

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4.6: Prostate adenocarcinoma; 4.7 Renal cell carcinoma

4.6: Prostate adenocarcinoma; 4.7 Renal cell carcinoma

... These may include financial interests (eg. owning stocks of a related company, having received honoraria, consultancy fees), research interests (research support by grants or otherwise)[r] ...

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The dual effect of MSCs on tumour growth and tumour angiogenesis.

The dual effect of MSCs on tumour growth and tumour angiogenesis.

... inhibit tumour growth in vivo Several reports have indicated that MSCs may influence tumour progression in different tumour types (reviewed by Klopp et ...First, tumour cells were implanted SC ...

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Monitoring of 3D breast carcinoma cell culture using proton magnetic resonance imaging

Monitoring of 3D breast carcinoma cell culture using proton magnetic resonance imaging

... both cell lines to the changes in tissue hydratation and protein content. In addition, our study showed that proton T 1 and T 2 relaxation times are not significantly different between the two cell lines. ...

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Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development

Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development

... and cell surface receptors on live CD45+Ly6G+ neutrophils at a single-cell level by flow ...MC cell proportions revealed four MCs highly abundant in tumor samples (Figure 2 G, green gates); here, two ...

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Modulating T Cell costimulation to prevent renal allograft rejection in nonhuman primates

Modulating T Cell costimulation to prevent renal allograft rejection in nonhuman primates

... T cell, reducing their recovery speed from T cell depletion, and prolonging allograft survival (Ayasoufi ...T cell egress from thymus and secondary lymphoid ...T cell trafficking into grafts ...

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