Rectal cancer
Preoperative hyperfractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective phase II trial
... in rectal cancer [6] , [9] , [13] , [24] and [48] ...Swedish rectal cancer trial (SRCT) have recently been confirmed by the investigators of the Dutch colorectal cancer group ...
11
Fertility preservation strategies for rectal cancer in reproductive-age women
... Despite rectal cancer is unusual before 40, fertility preservation (FP) remains a major concern for these age-reproductive ...of rectal cancer in a young ...
11
Effect of timing of surgery on survival after preoperative hyperfractionated accelerated radiotherapy (HART) for locally advanced rectal cancer (LARC): Is it a matter of days?
... Another interesting observation is a three- to four- fold increase of active matrix metalloproteinases (MMP) after radiotherapy [44,45]. These zinc- containing enzymes are actively involved in the degradation of the ...
9
The advantages of using endoscopic ultrasound in adult patients with early stage rectal cancer : a systematic review
... of rectal cancer; it examines the thickness of the rectal wall, assesses the depth of tumor invasion and helps in distinguishing between tumors localized to the rectal wall and tumors with ...
123
Predictive factors in locally advanced rectal cancer treated with preoperative hyperfractionated and accelerated radiotherapy.
... colorectal cancer are still important after neoadjuvant therapy is a question fre- quently asked by pathologists, and only sporadic studies with a systematic pathologic approach have attempted to answer ...in ...
8
Préoperative hyperfractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective trial.
... in rectal cancer [6,9,13,24,48] ...Swedish rectal cancer trial (SRCT) have recently been confirmed by the investigators of the Dutch colorectal cancer group ...
7
Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.
... with rectal carcinoma, pelvic recurrence is a major source of morbidity and ...Colorectal Cancer Group Trial [2] has confirmed that a short course of radiotherapy (RT) reduced the rate of pelvic recurrence ...
11
The role of COX-2 in rectal cancer treated with preoperative radiotherapy
... among the published literature about what should be the “standard” treatment and the primary endpoint in rectal cancer (survival, disease-free survival, local control, sphinc- ter sparing surgery or ...
7
CPT-11 and concomitant hyperfractionated accelerated radiotherapy induce efficient local control in rectal cancer patients: results from a phase II
... III rectal cancer was established based on controlled trials indicating a significant improvement of local control and overall survival (Swedish Rectal Cancer Trial, ...(Swedish Rectal ...
7
Short course chemotherapy followed by concomitant chemoradiotherapy and surgery in locally advanced rectal cancer: a randomized multicentric phase II study.
... cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is ...neoadjuvant rectal cancer trials: statistical evaluation based on the FFCD 9203 ...
6
Postoperative Radiation Therapy for Rectal Cancer: An Interim Analysis of a Prospective, Randomized Multicenter Trial in The Netherlands
... However, a definite trend (according to the analysis of the authors this trend was statistically significant!) toward a reduction of the local re- lapse rate in the irradi[r] ...
4
Cyclin D1 gene G870A polymorphism predicts response to neoadjuvant radiotherapy and prognosis in rectal cancer.
... Alexandre Ho-Pun-Cheung, Eric Assénat, Simon Thezenas, Frédéric Bibeau, Rouanet Philippe, David Azria, Dominic Cellier, Jean Grenier, Marc Ychou,.. Pierre Senesse, et al[r] ...
5
Validation of an appropriate reference gene for normalization of reverse transcription-quantitative polymerase chain reaction data from rectal cancer biopsies.: Normalization of RT-qPCR data in rectal cancer
... PGK1 Phosphoglycerate kinase 1 NM_000291 Glycolysis enzyme Medium RPLP0 Ribosomal protein, large, P0 NM_001002 Component of the 60S subunit Medium POLR2L Polymerase RNA II po[r] ...
3
Comprehensive molecular characterization of human colon and rectal cancer
... We integrated copy number, gene expression, methylation and pathway data using the PARADIGM software platform 35 . The analysis showed a number of new characteristics of CRC (Fig. 5a). For example, despite the diversity ...
9
Chronic pelvic pain and rectal prolapse invite consideration of enterocele
... All patients in this study had been referred to a tertiary unit (University Hospital, Rennes, France) between 2005 and 2015 for an anorectal complaint. Details were prospectively included in a dedicated database ...
17
Role of methalothionein in irradiated human rectal carcinoma.
... KEYWORDS: metallothionein, rectum, cancer, radiotherapy, in vitro. F ailure to control local tumor growth and recurrence is due to the acquired or inherent radioresistance of the tumors. Over the last decade, ...
6
Rectal and Urethro-Vesical Subregions for Toxicity Prediction After Prostate Cancer Radiation Therapy: Validation of Voxel-Based Models in an Independent Population
... with rectal bleeding, were not confirmed in the validation cohort as more predictive than the whole ...≥2 rectal bleeding were four times higher than in the development cohort, possibly due to the use of ...
18
Role of substance P and CGRP in PAR-2-induced rectal hyperalgesia in rats
... Version preprint Comment citer ce document : Guiard, B., Cenac, N., Garcia Villar, R., Vergnolle, N., Coelho, A.-M., Fioramonti, J., Bueno, L. (2001). Role of substance P and CGRP in PAR-2-induced rectal ...
5
Long-term impact of full-thickness rectal prolapse treatment on fecal incontinence.
... RESULTS Study population Among the 206 patients referred for a full-thickness rectal prolapse, 26 (12.6%) patients declined to complete the questionnaire, 8 were not able to do so, 9 patients died from unrelated ...
21
Risk of Rectal Neoplasia after Colectomy and Ileorectal Anastomosis for Ulcerative Colitis
... of rectal neoplasias after IRA for UC, some limitations have to be ...i.e. rectal carcinoma, and we considered separately colonic dysplasia and colonic carcinoma for the risk factor analysis, which make our ...
6