RECEPTOR SERINE / THREONINE KINASE
Role of the serine-threonine kinase PAK-1 in myxoma virus replication
... host serine-threonine kinases (STKs) as potential mediators of the permissive ...by receptor- mediated ...protein kinase inhibitors, many of which shared the ability to influence the activity ...
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A wheat cysteine-rich receptor-like kinase confers broad-spectrum resistance against Septoria tritici blotch
... Fig. 1 Map-based cloning of the Stb16q gene. a Scaffold1066 and Scaffold45305 from the Ae. tauschii physical map 23 were identi fied as co-segregating with Stb16q in the DH population derived from TA4152-19 × ND495. ...
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Structure-Function Similarities between a Plant Receptor-like Kinase and the Human Interleukin-1 Receptor-associated Kinase-4
... plant receptor-like kinases (RLKs) are monophyletic with respect to the kinase domain and share an evolutionary origin with the animal interleukin-1 receptor-associated kinase/Pelle- soluble ...
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Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases pim-1 and pim-3
... were LIF-deprived for 24 hrs, then restimulated with 10.000 U/ml of LIF for 1 hr. Withdrawal of LIF for 24 hrs did not induce loss of ES cell pluripotency (see Supplementary data 1). This stimulation protocol led to a ...
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Phosphorylation Of Histone Deacetylase 7 By Protein Kinase D Mediates T Cell Receptor-Induced Nur77 Expression And Apoptosis
... DISCUSSION During thymic education, negative selection of T cells is as- sociated with the activation of a specific apoptotic program. One of the crucial mediators of negative selection in thy- mocytes and T cell ...
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The role of RICTOR downstream of receptor tyrosine kinase in cancers
... the receptor serves as a docking site for the p85 regulatory subunit of PI3K recruiting the catalytic subunit of PI3K, p110, to the plasma ...phosphoinositol-dependent kinase-1 (PDK1) and AKT. AKT is then ...
11
Involvement of cyclic AMP response element binding protein (CREB) and estrogen receptor phosphorylation in the synergistic activation of the estrogen receptor by estradiol and protein kinase activators.
... Because transfected CREB could enhance transcription in both cell lines as well as restore synergistic transcription on the 2ERE reporter in SK-BR-3 cells, we examined whether ER and CREB could interact. We could not ...
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Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells
... 21. Cao W, Bover L, Cho M, Wen X, Hanabuchi S, Bao M, et al. Regulation of TLR7/9 responses in plasma- cytoid dendritic cells by BST2 and ILT7 receptor interaction. J Exp Med. 2009; 206(7):1603 –14. PMID: 19564354 ...
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Wheat receptor-kinase-like protein Stb6 controls gene-for-gene resistance to fungal pathogen <em>Zymoseptoria tritici</em>
... “Nevertheless, this gene will be useful in combination with other STB resistance genes, and our study provides tools for rapid lab-based tracing of Stb6 in wheat breeding lines,” says Kanyuka. Kanyuka also highlights the ...
2
Serine β-lactamases and penicillin-binding proteins
... the chromosome map) and the 799- to 844-amino acid PBP I B (encoded by ponB in the 3 . 3-min region of the map) are bifunctional, peptidoglycan synthesizing enzymes (59, 85 , 1 07 , 108). Their amino terminal domain is ...
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Primary deficiency of interleukin-1 receptor-associated kinase (IRAK-4) presenting as fatal pseudomonas aeruginosa bacteremia in two siblings
... Toll-like receptor (TLR) –interkeukin-1R (IL-1R) intracellular signal transduction pathway proteins, such as the interleukin (IL)-1 receptor-associated kinase 4 (IRAK-4) and myeloid differentiation ...
1
AXL receptor tyrosine kinase in breast cancer : defining novel substrates and pathways involved in cell motility and invasion
... Bien qu'il soit encore difficile de savoir comment les signaux d’AXL induisent son phénotype pro-invasif, notre travail au chapitre 3 vise à identifier des substrats et des voies de signalisation spécifiques qui sont ...
238
Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.: Dual effects of ALK on apoptosis : a new dependence receptor
... counteracted by the proliferative and pro-survival effect of the constitutively activated tyrosine kinase. We propose that apoptosis associated with inappropriate ALK expression could limit the tumorigenic effect ...
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Implication de la MAPK kinase kinase DLK dans la différenciation des kératinocytes
... En resume, nous avons appuye les premiers resultats associant un role a la proteine kinase DLK dans la differenciation des keratinocytes par l'etude de sa fonction specifique dans la d[r] ...
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ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling
... Factor Receptor (HGFR; MET), Human Epidermal Growth Factor Receptor 2 (HER2), and HER4 RTK ...find kinase inhibition generally reduces ADAM-10 and -17 activities, reduces subsequent RTK shedding, and ...
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Progesterone receptor isoforms PRA and PRB differentially contribute to breast cancer cell migration through interaction with focal adhesion kinase complexes.
... adhesion kinase (FAK) (Tang et ...tyrosine kinase functions as an integrator of multiple signaling pathways promoting formation and turnover of focal adhesion points, membrane ruffling, cell shape and ...
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Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology
... enhanced nucleoside phosphorylation produced by masitinib as the wild-type (Supplementary Fig. 15 ). Analysis of the effect of masitinib on UCK1 activity was performed using ATP as phosphate donor. PK/LDH coupled assay ...
12
Intestinal inflammation increases gastrointestinal threonine uptake and mucin synthesis in enterally fed minipigs
... for threonine is largely increased and that in the course of enteral nutrition containing free amino acids, the arterial supply is the preferential source of threonine used to meet the additional ...luminal ...
7
The ideal protein profile for growing-finishing pigs in precision feeding systems : threonine
... Page xxiii, Acknowledgements- Owing to a technical error, the author only acknowledged Agriculture and Agri-Food Canada (AAFC), Breton aliments, Swine innovation Por[r] ...
1
The ideal protein profile for growing-finishing pigs in precision feeding systems : threonine
... 2012). Threonine and Lys (and possibly Tryptophan) might be the only truly metabolic essential AA once they cannot be synthesized from α-keto acids (NRC, ...
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