RECEPTOR-LIKE KINASES
Plant Lectins and Lectin Receptor-Like Kinases: How Do They Sense the Outside?
... In plants, lectins have been early described as important players in defence against pathogens [ 15 ]. Most of them are secretory proteins routed either to the vacuole where they accumulate in large amounts in seeds, or ...
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Interaction of Medicago truncatula lysin motif receptor-like kinases, NFP and LYK3, produced in Nicotiana benthamiana induces defence-like responses
... Abstract Receptor(-like) kinases with Lysin Motif (LysM) domains in their extracellular region play crucial roles during plant interactions with microorganisms; ...unrelated ...
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Structure-Function Similarities between a Plant Receptor-like Kinase and the Human Interleukin-1 Receptor-associated Kinase-4
... plant receptor-like kinases (RLKs) are monophyletic with respect to the kinase domain and share an evolutionary origin with the animal interleukin-1 receptor-associated kinase/Pelle- soluble ...
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Lectin receptor kinases participate in protein-protein interactions to mediate plasma membrane-cell wall adhesions in Arabidopsis.
... the receptor-like kinases (RLK) and, based on the identity of the extracellular domains, belong to a gene subfamily, with at least 46 members (Shiu and Bleecker, 2001; Barre et ...
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Leucine-Rich Repeat Receptor Kinases are sporadically distributed in eukaryotic genomes
... a single-pass TM domain and an intracytoplasmic KD but differ in their extracellular domain (ECD) [5]. Mem- bers of the largest RLK subfamily, the leucine-rich repeat receptor-like kinases ...
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Protéine-kinases et cancer du rein : Découverte et validation d’une nouvelle combinaison d’inhibiteurs ciblant les protéine-kinases ATM et CK2
... We conducted a synthetic lethal screen on the CMBA platform (CEA- Grenoble), choosing 36 potential genes targets and 80 kinases inhibitors drugs. Each of the target gene was silenced by a transduction with shRNA ...
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L’œstrogène : un rôle potentiel dans la modulation de l’activation pro-inflammatoire des cellules endothéliales vasculaires par la voie du Toll-Like Receptor 2
... 1.4.3.3 La paroi vasculaire et la guérison vasculaire L’agression de l’endothélium de la paroi vasculaire par plusieurs facteurs de risques biologiques, à l’origine de la dysfonction endothéliale, conduit au ...
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Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels
... Fig. 1. Tie2-tTA;TRE-Notch4* mice developed AV shunts through enlargement of capillary-like vessels. (A and A ′) Two-photon time-lapse imaging of FITC- dextran –labeled AV connections in the cerebral cortex ...
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A wheat cysteine-rich receptor-like kinase confers broad-spectrum resistance against Septoria tritici blotch
... presence of only two candidate genes in this 272 kb interval, Crk6 and Unk1 (Fig. 1 ). Stb16q encodes a cysteine-rich receptor-like kinase. To func- tionally validate these two candidate genes a set of ...
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Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype.
... INTRODUCTION Schizophrenia is a devastating, complex and costly neuropsychiatric disorder that affects about 1% of the world’s population (Olesen et al, 2012). Schizophrenia is typically characterized by three symptom ...
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A wheat cysteine-rich receptor-like kinase confers broad-spectrum resistance against Septoria tritici blotch
... presence of only two candidate genes in this 272 kb interval, Crk6 and Unk1 (Fig. 1 ). Stb16q encodes a cysteine-rich receptor-like kinase. To func- tionally validate these two candidate genes a set of ...
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Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles.
... dependent signaling: stably transfected CHO cells expressing human TLR2 and/or TLR4 on 18. their cell surface and a reporter gene allowing detecting ligand-induced TLR activati[r] ...
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The Nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis
... Contexte La sclérose en plaques (SEP) est une maladie auto-immune déclenchée par une réaction inflammatoire anormale et caractérisée par la présence de plaque démyélinisantes dans le système nerveux central. Cette ...
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Corrigendum: New insights on leucine-rich repeats receptor-like kinase orthologous relationships in angiosperms
... A corrigendum on New Insights on Leucine-Rich Repeats Receptor-Like Kinase Orthologous Relationships in Angiosperms by Dufayard, J.-F., Bettembourg, M., Fischer, I., Droc, G., Guiderdoni, E., Périn, C., et ...
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CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults.
... benefit less from the protective effects of environmental exposures to TLR2 ligands on asthma. Further analyses of different asthma outcomes showed that TLR2/+596C was in particular associated with asthma in SPT ...
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Altered expression of type I insulin-like growth factor receptor in Crohn's disease
... In conclusion, we have shown an altered expression of IGF-1R transmurally in the bowel wall in CD, while it was present only in the mucosa in UC and absent in acute diverticulitis. This overexpression in the lamina ...
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Association of Killer Cell Immunoglobulin-Like Receptor Genes with Hodgkin's Lymphoma in a Familial Study.
... Citation: Besson C, Roetynck S, Williams F, Orsi L, Amiel C, et al (2007) Association of Killer Cell Immunoglobulin-Like Receptor Genes with Hodgkin’s Lymphoma in a Familial Study. PLoS ONE 2(5): e406. ...
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xopAC-triggered Immunity against Xanthomonas Depends on Arabidopsis Receptor-Like Cytoplasmic Kinase Genes PBL2 and RIPK
... XopAC avirulence functions likely depend on host target uridylylation No rapid HR-like symptoms were observed when Xcc or Pst expressing xopAC were infiltrated into Col-0 leaf tissues. Furthermore, in Pst, xopAC ...
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Régulation de la survie cellulaire par les kinases de la famille RAF
... des kinases RAF induit une réduction des niveaux d’expression des ARNm codant pour BAD ou BIM en même temps qu’une augmentation de ceux codant pour BCL2, BCLXL (B-cell lymphoma-extra large) ou MCL1 [19] ...Les ...
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Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models
... TLR4/MD-2 receptor complex (TLR4 being a transmembrane protein and MD-2 a soluble ...the receptor complex and the activation of different signaling pathways is elicited through MyD88 and TRIF molecules [98] ...
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