randomized trials
A Comparison of Imputation Strategies in Cluster Randomized Trials with Missing Binary Outcomes
... cluster randomized trials, clusters of subjects are randomized rather than subjects themselves, and missing outcomes are a concern as in individual randomized ...cluster randomized ...
34
CRTgeeDR: An R Package for Doubly Robust Generalized Estimating Equations Estimations in Cluster Randomized Trials with Missing Data
... cluster randomized trials (CRTs) where 1) observations within a cluster may be correlated, 2) observations in separate clusters are independent, 3) a monotone transformation of ex- pectation of the outcome ...
18
Reporting characteristics of non-primary publications of results of randomized trials: a cross-sectional review.
... cardiovascular trials published between 2002 and ...of randomized trials, identified major discrepancies in the specification of outcomes when comparing the trial protocol with the published ...
10
Causal inference methods for combining randomized trials and observational studies: a review
... both randomized trials and observational studies. Randomized trials isolate the effect of the treatment from that of unwanted (confounding) co-occuring ...combined randomized trial and ...
70
Randomized trials are the real hope for Covid-19 treatment
... conduct randomized studies using placebo ...clinical trials have been developed mainly randomized- trials exploring a large variety of drugs or treatment procedures (Figure ...
2
Preserving equipoise and performing randomized trials for COVID-19 social distancing interventions.
... randomized controlled trials. Social Science & Medicine 210, 2–21. Flaxman S, Mishra S, Gandy A, Unwin HJT, Mellan TA, Coupland H, Whittaker C, Zhu H, Berah T, Eaton JW, Monod M, Perez-Guzman PN, Schmit ...
8
Association between trial registration and positive study findings: cross sectional study (Epidemiological Study of Randomized Trials—ESORT)
... for trials that were not reported as registered or did not provide a trial regis- tration number in the published ...Clinical Trials Registry Platform (WHO ICTRP), the EU Clinical Trials Register, ...
8
Review of recent Methodological Developments in group-randomized trials: Part 1 - Design
... Pseudo-Cluster Randomized Trial (PCRT)† E: Individually Randomized Group Treatment (IGRT) Trial Groups are defined as the network contacts of an index disease case and those groups of contacts are then ...
31
Neglected external validity in reports of randomized trials: The example of hip and knee osteoarthritis.
... nonrandomised trials, observational studies (cohort and case-control studies), extended follow-up trials ...nontherapeutic trials (metrological studies, epidemiological studies), pathophysiological ...
32
Review of recent Methodological Developments in group-randomized trials: Part 2 - Analysis
... analysis of cluster randomized controlled trials with a binary outcome: the Community 703. Hypertension Assessment Trial (CHAT)[r] ...
29
Intervention effect estimates in cluster randomized versus individually randomized trials: a meta-epidemiological study
... of trials, it might suggest that CRTs and IRTs lead to different estimands and therefore the interpretations of the results are different; CRTs keep existing ‘social units’ in which participants can ...
12
Intracluster correlation coefficients in the Greater Mekong Subregion for sample size calculations of cluster randomized malaria trials Malaria Journal
... general, trials that use individual randomization are statistically more efficient than cluster randomized tri- als (CRTs) because the responses of individuals belong- ing to the same cluster tend to be ...
10
Cardiovascular adverse events of BRAF and/or MEK inhibitors in cancer patients: a systematic review and meta-analysis of placebo randomized- controlled trials
... identifying randomized trials in MEDLINE: sensitivity maximizing version (2008 revision) filter in MEDLINE and the search filters for identifying randomized trials in EMBASE that are described ...
55
Impact of a targeted monitoring on data-quality and data-management workload of randomized controlled trials a prospective comparative study
... clinical trials have been described [16,30,31], most of them combining on-site and centralized ...cluster-randomized trials both compared the efficacy of a risk- based monitoring strategy with a ...
27
Primary Thromboprophylaxis in Ambulatory Pancreatic Cancer Patients Receiving Chemotherapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
... It has been suggested that PC patients receiving chemotherapy may require higher doses of anticoagulant for VTE prevention since dalteparin was administered at therapeutic doses in the FRAGEM trial [ 25 ]. On the other ...
17
Efficacy of Oral Vitamin Supplementation in Inflammatory Rheumatic Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
... 17. Stamp, L.K.; O’Donnell, J.L.; Frampton, C.; Drake, J.; Zhang, M.; Barclay, M.; Chapman, P.T. A Pilot Randomized Controlled Double-Blind Trial of High- Versus Low-Dose Weekly Folic Acid in People With ...
18
Evidence Type Classification in Randomized Controlled Trials
... Abstract Randomized Controlled Trials (RCT) are a common type of experimental studies in the medical domain for evidence-based decision making. The ability to automatically extract the arguments proposed ...
7
Robust estimation of the expected survival probabilities from high-dimensional Cox models with biomarker-by-treatment interactions in randomized clinical trials
... a randomized clinical trial to estimate the expected treatment effect according to dif- ferent values of the biomarkers included in the model, and to estimate survival probabilities for individual patients with ...
12
University Certificate in Clinical Trials
... The advantages for the world of research in Belgium Clinical trials contribute to the development of scientific knowledge and innovation in Belgium. Belgian researchers and research centers thus remain at the ...
24
Health-related quality of life in cancer patients treated with immune checkpoint inhibitors: A systematic review on reporting of methods in randomized controlled trials
... Reporting Trials (CONSORT) group published the CON- SORT PRO extension in 2013; the Minimum Standard Checklist for evaluating HRQOL Outcomes in Cancer Clinical Trials by Efficace et ...
19